(Q40171692)

18 September 2017

title

Negative regulation of Pim-1 protein kinase levels by the B56beta subunit of PP2A. (English)

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18 September 2017

J Ma

1

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18 September 2017

H K Arnold

2

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18 September 2017

M B Lilly

3

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18 September 2017

R C Sears

4

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18 September 2017

A S Kraft

5

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18 September 2017

language of work or name

English

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publication date

12 February 2007

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18 September 2017

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18 September 2017

volume

26

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18 September 2017

issue

35

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18 September 2017

page(s)

5145-5153

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210323

18 September 2017

exact match

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cites work

Mice bearing the E mu-myc and E mu-pim-1 transgenes develop pre-B-cell leukemia prenatally

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

Targeting PIM kinases impairs survival of hematopoietic cells transformed by kinase inhibitor-sensitive and kinase inhibitor-resistant forms of Fms-like tyrosine kinase 3 and BCR/ABL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

The survival kinases Akt and Pim as potential pharmacological targets

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Protein phosphatase 2A regulatory subunit B56alpha associates with c-myc and negatively regulates c-myc accumulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Involvement of PP2A in viral and cellular transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

The serine/threonine kinase Pim-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

The use of okadaic acid to elucidate the intracellular role(s) of protein phosphatase 2A: lessons from the mast cell model system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Sil phosphorylation in a Pin1 binding domain affects the duration of the spindle checkpoint

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Identification of specific PP2A complexes involved in human cell transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Pim family kinases enhance tumor growth of prostate cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Pim serine/threonine kinases regulate the stability of Socs-1 protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Overexpression of Pim-1 during progression of prostatic adenocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Murine leukemia virus-induced T-cell lymphomagenesis: Integration of proviruses in a distinct chromosomal region

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Myc-driven murine prostate cancer shares molecular features with human prostate tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Lymphocyte transformation by Pim-2 is dependent on nuclear factor-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

PP2A: the expected tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Pim-1 is up-regulated by constitutively activated FLT3 and plays a role in FLT3-mediated cell survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Constitutively activated FLT3 phosphorylates BAD partially through pim-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Protein phosphatase 2A regulates the stability of Pim protein kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Regulation of the transcriptional activity of c-Fos by ERK. A novel role for the prolyl isomerase PIN1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Expression, purification, crystallization and preliminary crystallographic analysis of human Pim-1 kinase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Structural basis of constitutive activity and a unique nucleotide binding mode of human Pim-1 kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Bortezomib: proteasome inhibition as an effective anticancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the A alpha subunit gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Alterations in protein phosphatase 2A subunit interaction in human carcinomas of the lung and colon with mutations in the A beta subunit gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

A functional role for the B56 alpha-subunit of protein phosphatase 2A in ceramide-mediated regulation of Bcl2 phosphorylation status and function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Pim-1 kinase stability is regulated by heat shock proteins and the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Pin1 acts catalytically to promote a conformational change in Cdc25.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

PP2A fulfills its promises as tumor suppressor: which subunits are important?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Distinct protein phosphatase 2A heterotrimers modulate growth factor signaling to extracellular signal-regulated kinases and Akt

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Predisposition to lymphomagenesis in pim-1 transgenic mice: cooperation with c-myc and N-myc in murine leukemia virus-induced tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Overexpression of PIM-1 is a potential biomarker in prostate carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Pin1 modulates the structure and function of human RNA polymerase II.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210323

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210323

1 reference

Dimensions Publication ID

18 September 2017

1003866059

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1 reference