(Q40174527)

18 September 2017

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title

Biology and biochemistry of platelet-activating factor (English)

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18 September 2017

J T O'Flaherty

1

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PubMed ID

6370406

18 September 2017

R L Wykle

series ordinal

2

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18 September 2017

1 September 1983

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Clinical reviews in allergy

18 September 2017

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18 September 2017

1

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18 September 2017

3

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18 September 2017

353-367

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Production and release of platelet-activating factor (PAF); dissociation from degranulation and superoxide production in the human neutrophil

18 September 2017

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12 December 2020

Stimulation of human neutrophil degranulation with 1-O-octadecyl-2-O-acetyl-SN-glyceryl-3-phosphorylcholine: modulation by inhibitors of arachidonic acid metabolism

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12 December 2020

Effects on the Pulmonary Circulation of Suddenly Induced Intravascular Aggregation of Blood Platelets

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12 December 2020

Release of platelet-activating factor and histamine. I. Effect of immune complexes, complement and neutrophils on human and rabbit mastocytes and basophils

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12 December 2020

Release of 1-O-alkylglyceryl 3-phosphorylcholine, O-deacetyl platelet-activating factor, from leukocytes: chemical ionization mass spectrometry of phospholipids

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12 December 2020

Ether lipid content and fatty acid distribution in rabbit polymorphonuclear neutrophil phospholipids

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12 December 2020

One, two, three or more pathways for platelet aggregation

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12 December 2020

Studies on the mechanism of the Shwartzman phenomenon; certain factors involved in the production of the local hemorrhagic necrosis

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12 December 2020

THE ROLE OF MICRO-EMBOLISM IN THE PRODUCTION OF IRREVERSIBLE SHOCK

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12 December 2020

Platelet-activating factor effects on pulmonary ultrastructure in rabbits

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12 December 2020

Leukotriene B4: An inflammatory mediator In vivo

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12 December 2020

Molecular pathobiology of acetyl glyceryl ether phosphorylcholine: evidence for the structural and functional identity with platelet-activating factor.

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12 December 2020

Platelet activating factor (PAF-acether): total synthesis of 1-O-octadecyl 2-O-acetyl sn-glycero-3-phosphoryl choline

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12 December 2020

Mechanisms of bronchoconstriction and of thrombocytopenia induced by collagen in the guinea pig

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12 December 2020

Structural analysis of purified platelet-activating factor by lipases

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12 December 2020

Antihypertensive activity of an alkyl ether analog of phosphatidylcholine

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12 December 2020

AGEPC (platelet activating factor) induced stimulation of rabbit platelets: effects on phosphatidylinositol, di- and triphosphoinositides and phosphatidic acid metabolism

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12 December 2020

Role of extracellular calcium and neutrophil degranulation responses to 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine

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12 December 2020

Activation and desensitization of platelets by platelet-activating factor (PAF) derived from IgE-sensitized basophils. I. Characteristics of the secretory response

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12 December 2020

Intravascular aggregation and pulmonary sequestration of platelets during IgE-induced systemic anaphylaxis in the rabbit: abrogation of lethal anaphylactic shock by platelet depletion

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12 December 2020

Evidence for the involvement of IgE-basophil system in acute serum sickness

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12 December 2020

The role played by leucocytes and platelets in anaphylactic and peptone shock.

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12 December 2020

Monocyte aggregation and superoxide anion release in response to formyl-methionyl-leucyl-phenylalanine (FMLP) and platelet-activating factor (PAF)

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12 December 2020

A specific acetylhydrolase for 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (a hypotensive and platelet-activating lipid)

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12 December 2020

Release of platelet-activating factor (PAF-acether) and arachidonic acid metabolites from alveolar macrophages

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12 December 2020

Haemodynamic changes resulting from thrombin induced intravascular coagulation

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12 December 2020

1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet-activating factor) stimulates calcium influx in rabbit platelets

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12 December 2020

Platelet-activating factor, a new mediator of anaphylaxis and immune complex deposition from rabbit and human basophils

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12 December 2020

Thrombin-induced formation of a polar lipid material within platelets that possesses platelet-activating activity

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12 December 2020

Desensitization of the human neutrophil degranulation response: Studies with 5,12-dihydroxy-6,8,10,14-eicosatetraenoic acid

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12 December 2020

Neutrophil aggregation and swelling induced by chemotactic agents

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12 December 2020

Acute immune complex disease in rabbits. The role of complement and of a leukocyte-dependent release of vasoactive amines from platelets

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12 December 2020

The behaviour of platelets in vivo

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12 December 2020

Plumonary responses to intravascular platelet aggregation in the cat.

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12 December 2020

The role of platelet-activating factor in platelet aggregation

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12 December 2020

THE PHYSIOLOGY OF THE IMMEDIATE REACTION OF ANAPHYLAXIS IN THE GUINEA-PIG.

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12 December 2020

Is platelet-activating factor (PAF-acether) synthesis by murine peritoneal cells (PC) a two-step process?

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12 December 2020

Anaphylactic actions of platelet-activating factor.

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12 December 2020

Inhibition of platelet adenylate cyclase by 1-O-alkyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine (platelet-activating factor)

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12 December 2020

Neutropenia induced by platelet-activating factor (PAF-acether) released from neutrophils: the inhibitory effect of prostacyclin (PGI2).

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12 December 2020

Structural analogs of platelet-activating factor (PAF-acether)

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12 December 2020

Circulatory and Ventilatory Effects of Induced Platelet Aggregation and Their Inhibition by Acetylsalicylic Acid

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12 December 2020

Effects of acetyl glyceryl ether phosphorylcholine on human platelet function in vitro

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12 December 2020

Neutrophil-degranulating action of 5,12-dihydroxy-6,8,10,14-eicosatetraenoic acid and 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine. Comparison with other degranulating agents

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12 December 2020

Immunologic release in the rat peritoneal cavity lipid chemotactic and chemokinetic factors for polymorphonuclear leukocytes

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12 December 2020

Platelet-activating factor and macrophages. I. Evidence for the release from rat and mouse peritoneal macrophages and not from mastocytes

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12 December 2020

THE INDUCED SUSCEPTIBILITY OF THE GUINEA-PIG TO THE TOXIC ACTION OF THE BLOOD SERUM OF THE HORSE

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12 December 2020

Release of platelet-activating factor in human pathology. I. Evidence for the occurrence of basophil degranulation and release of platelet-activating factor in systemic lupus erythematosus

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12 December 2020

Potent platelet stimulating activity of enantiomers of acetyl glyceryl ether phosphorylcholine and its methoxy analogues

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12 December 2020

Platelet-activating factor acether (PAF-acether) involvement in acute inflammatory and pain processes

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12 December 2020

Pathobiology of the intravenous infusion of acetyl glyceryl ether phosphorylcholine (AGEPC), a synthetic platelet-activating factor (PAF), in the rabbit.

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12 December 2020

Non-platelet-mediated vascular actions of 1-O-alkyl-2-acetyl-sn-3-glyceryl phosphorycholine (a synthetic PAF)

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12 December 2020

The physiological action of beta-iminazolylethylamine

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12 December 2020

Acetyl glyceryl ether phosphorylcholine. Intravascular alterations following intravenous infusion into the baboon

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12 December 2020

Effect of intravascular complement activation on granulocyte adhesiveness and distribution

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12 December 2020

Phorbol myristate acetate: in vivo effects upon neutrophils, platelets, and lung

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12 December 2020

AN ELECTROCARDIOGRAPHIC STUDY OF THE ANAPHYLACTIC RABBIT.

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12 December 2020

Acyl dihydroxyacetone phosphate: Precursor of alkyl ethers

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12 December 2020

The release of a platelet-activating factor by stimulated rabbit neutrophils

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12 December 2020

The binding of platelet-activating factor (PAF) to polymorphonuclear neutrophils (PMN) as a trigger for the immune-induced PMN aggregation

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12 December 2020

Platelet-activating factor induces a platelet-dependent bronchoconstriction unrelated to the formation of prostaglandin derivatives

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12 December 2020

Release of platelet-activating factor (PAF-acether) from alveolar macrophages by the calcium ionophore A23187 and phagocytosis

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12 December 2020

Activation of 1-alkyl-2-lysoglycero-3-phosphocholine. Acetyl-CoA transferase during phagocytosis in human polymorphonuclear leukocytes

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12 December 2020

The release of histamine and 5‐hydroxytryptamine (serotonin) from platelets by antigen‐antibody reactions (in vitro)

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12 December 2020

Stereospecific activity of 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine and comparison of analogs in the degranulation of platelets and neutrophils

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12 December 2020

The role of PMN-leucocyte lysosomes in tissue injury, inflammation and hypersensitivity. VI. The participation of the PMN-leucocyte and the blood platelet in systemic aggregate anaphylaxis

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12 December 2020

Thromboxane B2 (TxB2) release during IgE anaphylaxis in the rabbit.

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12 December 2020

Background and present status of research on platelet-activating factor (PAF-acether).

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12 December 2020

Novel effects of 1-O-hexadecyl-2-acyl-sn-glycero-3-phosphorycholine mediators on human leukocyte function: delineation of the specific roles of the acyl substituents

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12 December 2020

Release of a slow-reacting substance from rabbit platelets

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12 December 2020

Destruction of rabbit platelets in the allergic response of sensitized leukocytes. II. Evidence for basophil involvement.

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12 December 2020

Release, purification, and characterization of platelet-activating factor (PAF).

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12 December 2020

Biosynthesis of platelet-activating factor (PAF-ACETHER). II. Involvement of phospholipase A2 in the formation of PAF-ACETHER and lyso-PAF-ACETHER from rabbit platelets

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12 December 2020

Hemodialysis leukopenia. Pulmonary vascular leukostasis resulting from complement activation by dialyzer cellophane membranes

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12 December 2020

Platelet-activating factor. Evidence for 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine as the active component (a new class of lipid chemical mediators)

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12 December 2020

The Release of Prostaglandin-Like Substances during Platelet Aggregation and Pulmonary Microembolism

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12 December 2020

Role of prostaglandin synthesis in rabbit platelet activation induced by basophil-derived platelet-activating factor

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12 December 2020

Immunological induction of increased vascular permeability. I. A rabbit passive cutaneous anaphylactic reaction requiring complement, platelets, and neutrophils

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12 December 2020

Mediators of immune-complex-induced aggregation of polymorphonuclear neutrophils. II. Platelet-activating factor as the effector substance of immune-induced aggregation

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12 December 2020

Effect of synthetic PAF-acether on human neutrophil function

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12 December 2020

Destruction of rabbit platelets in the allergic response of sensitized leukocytes. I. Demonstration of a fluid phase intermediate

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12 December 2020

Studies on heart anaphylaxis. V. Cross-desensitisation between antigen, anaphylatoxin, and compound 48-80 in the guinea-pig papillary muscle

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12 December 2020

Platelet-activating factor in anaphylaxis and phagocytosis. I. Release from human peripheral polymorphonuclears and monocytes during the stimulation by ionophore A23187 and phagocytosis but not from degranulating basophils

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12 December 2020

Release of vasoactive amines from rabbit platelets induced by sensitized mononuclear leukocytes and antigen

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12 December 2020

Intravascular effects of IgE antibody upon basophils,, neutrophils, platelets and blood coagulation in the rabbit

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12 December 2020

Activities of enzymes that metabolize platelet-activating factor (1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine) in neutrophils and eosinophils from humans and the effect of a calcium ionophore

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12 December 2020

IgE-induced respiratory and circulatory changes during systemic anaphylaxis in the rabbit

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12 December 2020

Selective desensitization of neutrophils: further studies with 1-O-alkyl-sn-glycero-3-phosphocholine analogues

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12 December 2020

In vivo observations of the vascular reactions to large doses of horse serum using the rabbit ear chamber technique

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12 December 2020

Platelet-activating factor (PAF-acether) secretion from platelets: effect of aggregating agents

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12 December 2020

Aggregation of rabbit platelets by platelet-activating factor is independent of the release reaction and the arachidonate pathway and inhibited by membrane-active drugs

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12 December 2020

Influence of alkyl ether chain length of acetyl glyceryl ether phosphorylcholine and its ethanolamine analog on biological activity toward rabbit platelets

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12 December 2020

Biosynthesis of platelet-activating factor. I. Evidence for an acetyl-transferase activity in murine macrophages

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12 December 2020

Proceedings: Role of platelet aggregation in bronchoconstriction in guinea-pigs

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12 December 2020

Bronchoconstriction induced by intratracheal administration of platelet-activating factor (PAF-acether) in baboons

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12 December 2020

Activation of platelets by platelet-activating factor (PAF) derived from IgE-sensitized basophils. II. The role of serine proteases, cyclic nucleotides, and contractile elements in PAF-induced secretion

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12 December 2020

Physicochemical and functional identity of rabbit platelet-activating factor (PAF) released in vivo during IgE anaphylaxis with PAF released in vitro from IgE sensitized basophils

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12 December 2020

Activation of human neutrophils with 1-O-hexadecyl/octadecyl-2-acetyl-sn-glycerol-3-phosphorylcholine (platelet activating factor)

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12 December 2020

Role of granulocytes in immune complex-induced tissue injuries

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12 December 2020

Platelet activating factor. Stimulation of the lipoxygenase pathway in polymorphonuclear leukocytes by 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine

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12 December 2020

Platelet activating factor (1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine). Activity of analogs lacking oxygen at the 2-position

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12 December 2020

Specificity of lysophospholipase D.

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12 December 2020

Modification of the polar head group of acetyl glyceryl ether phosphorylcholine and subsequent effects upon platelet activation

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12 December 2020

Generation and release of platelet-activating factor (PAF) from enriched preparations of rabbit basophils; failure of human basophils to release PAF

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12 December 2020

Complement (C5-a)-induced granulocyte aggregation in vitro. A possible mechanism of complement-mediated leukostasis and leukopenia

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12 December 2020

Requirement of Cytidine Derivatives in the Biosynthesis of O-Alkyl Phospholipids

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12 December 2020

Induction of leukocytic infiltrates in rabbit skin by acetyl glyceryl ether phosphorylcholine

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12 December 2020

Substrate specificity in the biocleavage of the O-alkyl bond: 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (a hypotensive and platelet-activating lipid) and its metabolites

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12 December 2020

The release of four mediators of immediate hypersensitivity from human leukemic basophils

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12 December 2020

PLASMA AND BLOOD HISTAMINE IN VARIOUS TYPES OF SHOCK IN GUINEA PIGS

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12 December 2020

1-O-Alkyl-sn-glyceryl-3-phosphorylcholines: a novel class of neutrophil stimulants

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12 December 2020

Effect of platelet-activating factor (PAF) on human platelets

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12 December 2020

Respiratory and circulatory alterations induced by acetyl glyceryl ether phosphorylcholine, a mediator of IgE anaphylaxis in the rabbit

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12 December 2020

Pharmacological modulation of platelet-activating factor (PAF) release from rabbit leucocytes. I. Role of cAMP

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12 December 2020

Platelet-activating factor (PAF-acether): Present status

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12 December 2020

[Platelet aggregation and platelet activating factor (author's transl)]

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12 December 2020

Platelet-activating factor (PAF) in experimentally-induced rabbit acute serum sickness: role of basophil-derived PAF in immune complex deposition

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12 December 2020

Human neutrophil-derived platelet activating factor

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12 December 2020

The role of acyldihydroxyacetone phosphate, reduced nicotinamide adenine dinucleotide, and reduced nicotinamide adenine dinucleotide phosphate in the biosynthesis of O-alkyl glycerolipids by microsomal enzymes of Ehrlich ascites tumor

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12 December 2020

Evidence for 5,12-dihydroxy-6,8,10,14-eicosatetraenoate as a mediator of human neutrophil aggregation

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12 December 2020

Present concepts on the mechanisms of platelet aggregation

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12 December 2020

Identification of platelet activating factor isolated from rabbit basophils as acetyl glyceryl ether phosphorylcholine

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12 December 2020

Release of platelet-activating factor (PAF) and histamine. II. The cellular origin of human PAF: monocytes, polymorphonuclear neutrophils and basophils

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12 December 2020

Platelet-activating factor and analogues: comparative studies with human neutrophils and rabbit platelets

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12 December 2020

IgE-induced release of a platelet-activating factor from rabbit lung

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12 December 2020

Physical and chemical properties of platelet-activating factor obtained from human neutrophils and monocytes and rabbit neutrophils and basophils

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12 December 2020

The Significance of Platelet Aggregation in Anaphylactic Shock in Rats

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12 December 2020

Biosynthetic labelling of platelet activating factor from radioactive acetate by stimulated platelets

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12 December 2020

Biosynthesis of 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet activating factor and a hypotensive lipid) by cholinephosphotransferase in various rat tissues

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12 December 2020

[Hemodynamic changes of adenosine diphosphate, adenosine triphosphate, and thrombin in relation to their platelet-aggregating activity.]

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12 December 2020

Enzymatic synthesis of 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine, a hypotensive and platelet-aggregating lipid.

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12 December 2020

Platelet aggregation and release of ADP, serotonin and histamine associated with phagocytosis of antigen-antibody complexes

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12 December 2020

Neutrophil responses to platelet-activating factor

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12 December 2020

Basophil-derived platelet-activating factor (PAF) as an in vivo mediator of acute allergic reactions: demonstration of specific desensitization of platelets to PAF during IgE-induced anaphylaxis in the rabbit

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12 December 2020

Semi-synthesis and proposed structure of platelet-activating factor (P.A.F.): PAF-acether an alkyl ether analog of lysophosphatidylcholine

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12 December 2020

The binding of rabbit basophil-derived platelet-activating factor to rabbit platelets

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12 December 2020

Identification of O-alkyldihydroxyacetone phosphate, O-alkyldihydroxyacetone, and diacyl glyceryl ethers after enzymic synthesis.

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12 December 2020

New total synthesis and high resolution 1H NMR spectrum of platelet-activating factor, its enantiomer and racemic mixtures

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12 December 2020

Preliminary studies of an acid-labile factor (ALF) in human sera that inactivates platelet-activating factor (PAF)

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12 December 2020

Lysophosphatidic acid-induced aggregation of human and feline platelets: structure-activity relationship

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12 December 2020

Leukocyte-dependent histamine release from rabbit platelets. The role of IgE, basophils, and a platelet-activating factor

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12 December 2020

Pulmonary vascular responses to adenosine diphosphate

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12 December 2020

The immunological generation of a platelet-activating factor and a platet-lytic factor in the rat

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12 December 2020

In vivo metabolism of a new class of biologically active phospholipids: 1-alkyl-2-acetyl--glycero-3-phosphocholine, a platelet activating-hypotensive phospholipid

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12 December 2020

Neutropenia induced by systemic infusion of 5,12-dihydroxy-6,8,10,14-eicosatetraenoic acid: correlation with its in vitro effects upon neutrophils

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12 December 2020

Identifiers

PubMed ID

6370406

1 reference

PubMed ID

6370406