(Q40178873)

English

Engineering a disulfide bond to stabilize the calcium-binding loop of activated protein C eliminates its anticoagulant but not its protective signaling properties

scientific article published on 25 January 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Engineering a disulfide bond to stabilize the calcium-binding loop of activated protein C eliminates its anticoagulant but not its protective signaling properties (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

anticoagulation

1 reference

based on heuristic

inferred from title

drotrecogin alfa

1 reference

based on heuristic

inferred from title

author name string

Jong-Sup Bae

1

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Likui Yang

2

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Chandrashekhara Manithody

3

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Alireza R Rezaie

4

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

language of work or name

0 references

publication date

25 January 2007

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

282

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

12

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

9251-9259

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Structure and function of protein C.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

Gene expression profile of antithrombotic protein c defines new mechanisms modulating inflammation and apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

Activation of endothelial cell protease activated receptor 1 by the protein C pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

Activated protein C variants with normal cytoprotective but reduced anticoagulant activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

Efficacy and safety of recombinant human activated protein C for severe sepsis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

The crystal structure of the endothelial protein C receptor and a bound phospholipid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

Residue 225 determines the Na(+)-induced allosteric regulation of catalytic activity in serine proteases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

Activation of protein C by the thrombin-thrombomodulin complex: cooperative roles of Arg-35 of thrombin and Arg-67 of protein C

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

Contribution of basic residues of the 70-80-loop to heparin binding and anticoagulant function of activated protein C.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

Isolation and characterization of a cDNA encoding a human liver/bone/kidney-type alkaline phosphatase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

Exosite-dependent regulation of factor VIIIa by activated protein C.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

Inhibition of staurosporine-induced apoptosis of endothelial cells by activated protein C requires protease-activated receptor-1 and endothelial cell protein C receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

A fluorometric assay for the quantitation of cell adherence to endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

Vascular endothelial growth factor expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin through nuclear factor-kappa B activation in endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

Insulin-like growth factor-1 enhances inflammatory responses in endothelial cells: role of Gab1 and MEKK3 in TNF-alpha-induced c-Jun and NF-kappaB activation and adhesion molecule expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

PAR1 cleavage and signaling in response to activated protein C and thrombin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

Secondary substrate-binding exosite in the serine protease domain of activated protein C important for cleavage at Arg-506 but not at Arg-306 in factor Va.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

Molecular characterization of an extended binding site for coagulation factor Va in the positive exosite of activated protein C.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M610547200

21 January 2018

Identifiers

10.1074/JBC.M610547200

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

ResearchGate publication ID

0 references

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