(Q40184745)

18 September 2017

The mouse soluble GFRalpha4 receptor activates RET independently of its ligand persephin (English)

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18 September 2017

Yang J

1

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18 September 2017

Runeberg-Roos P

series ordinal

2

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18 September 2017

Leppänen VM

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3

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18 September 2017

Saarma M

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4

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18 September 2017

language of work or name

English

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publication date

8 January 2007

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18 September 2017

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18 September 2017

26

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18 September 2017

26

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18 September 2017

3892-3898

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210161

18 September 2017

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cites work

The GDNF family: signalling, biological functions and therapeutic value

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210161

Mechanism of activation of the ret proto-oncogene by multiple endocrine neoplasia 2A mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210161

Distinct structural elements in GDNF mediate binding to GFRalpha1 and activation of the GFRalpha1-c-Ret receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210161

Ultraviolet light induces redox reaction-mediated dimerization and superactivation of oncogenic Ret tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210161

The RET proto-oncogene: a molecular therapeutic target in thyroid cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210161

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210161

The structure of GFRalpha1 domain 3 reveals new insights into GDNF binding and RET activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210161

Human glial cell line-derived neurotrophic factor receptor alpha 4 is the receptor for persephin and is predominantly expressed in normal and malignant thyroid medullary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210161

Expression and alternative splicing of mouse Gfra4 suggest roles in endocrine cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210161

Ablation of persephin receptor glial cell line-derived neurotrophic factor family receptor alpha4 impairs thyroid calcitonin production in young mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210161

Raster3D: photorealistic molecular graphics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210161

Persephin, a novel neurotrophic factor related to GDNF and neurturin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210161

Released GFRalpha1 potentiates downstream signaling, neuronal survival, and differentiation via a novel mechanism of recruitment of c-Ret to lipid rafts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210161

SWISS-MODEL: An automated protein homology-modeling server

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210161

Determinants of ligand binding specificity in the glial cell line-derived neurotrophic factor family receptor alpha S.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210161

GFRalpha-mediated localization of RET to lipid rafts is required for effective downstream signaling, differentiation, and neuronal survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210161

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210161

A model for GFR alpha 4 function and a potential modifying role in multiple endocrine neoplasia 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210161

The first cysteine-rich domain of the receptor GFRalpha1 stabilizes the binding of GDNF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210161

Structure of artemin complexed with its receptor GFRalpha3: convergent recognition of glial cell line-derived neurotrophic factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210161

PSPN/GFRalpha4 has a significantly weaker capacity than GDNF/GFRalpha1 to recruit RET to rafts, but promotes neuronal survival and neurite outgrowth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210161

21 January 2018

Identifiers

DOI

10.1038/SJ.ONC.1210161

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Dimensions Publication ID

18 September 2017

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1 reference