(Q40186234)

English

Systems pharmacology of the nerve growth factor pathway: use of a systems biology model for the identification of key drug targets using sensitivity analysis and the integration of physiology and pharmacology

scientific article published on April 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

Systems pharmacology of the nerve growth factor pathway: use of a systems biology model for the identification of key drug targets using sensitivity analysis and the integration of physiology and pharmacology (English)

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

1 reference

based on heuristic

inferred from title

author name string

Neil Benson

1

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

Tomomi Matsuura

2

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

Sergey Smirnov

3

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

Oleg Demin

4

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

Hannah M Jones

5

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

Pinky Dua

6

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

Piet H van der Graaf

7

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

publication date

1 April 2013

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

Interface Focus

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

3

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

2

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

20120071

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

Integrated pharmacometrics and systems pharmacology model-based analyses to guide GnRH receptor modulator development for management of endometriosis

1 reference

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CPT: Pharmacometrics and Systems Pharmacology

1 reference

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Predicting nonlinear changes in bone mineral density over time using a multiscale systems pharmacology model

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1 reference

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Reducing systems biology to practice in pharmaceutical company research; selected case studies

1 reference

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Systems biology: an approach.

1 reference

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NGF uptake and retrograde signaling mechanisms in sympathetic neurons in compartmented cultures

1 reference

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Are animal models predictive for humans?

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Effect of anti-NGF antibodies in a rat tibia fracture model of complex regional pain syndrome type I.

1 reference

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Functions and mechanisms of retrograde neurotrophin signalling

1 reference

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p53 is a NF-Y- and p21-independent, Sp1-dependent repressor of cyclin B1 transcription

1 reference

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Can the pharmaceutical industry reduce attrition rates?

1 reference

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22 September 2017

Neurotrophins and their receptors: a convergence point for many signalling pathways

1 reference

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22 September 2017

The druggable genome

1 reference

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22 September 2017

Probing the binding mechanism and affinity of tanezumab, a recombinant humanized anti-NGF monoclonal antibody, using a repertoire of biosensors

1 reference

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25 September 2017

The mammalian MAPK/ERK pathway exhibits properties of a negative feedback amplifier

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17 June 2018

Has the time come for predictive computer modeling in CNS drug discovery and development?

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20 August 2018

Multiscale kinetic modeling of liposomal Doxorubicin delivery quantifies the role of tumor and drug-specific parameters in local delivery to tumors

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20 August 2018

Cross-membrane signal transduction of receptor tyrosine kinases (RTKs): from systems biology to systems pharmacology

1 reference

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20 August 2018

Systems pharmacology: bridging systems biology and pharmacokinetics-pharmacodynamics (PKPD) in drug discovery and development.

1 reference

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20 August 2018

Tanezumab for the treatment of pain from osteoarthritis of the knee.

1 reference

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Structure-based maximal affinity model predicts small-molecule druggability.

1 reference

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International alliances for quantitative modeling in systems biology

1 reference

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20 August 2018

Nerve growth factor mediates hyperalgesia and cachexia in auto-immune arthritis.

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Quantitative structure-pharmacokinetics relationships: I. Development of a whole-body physiologically based model to characterize changes in pharmacokinetics across a homologous series of barbiturates in the rat.

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Dynamics of the Ras/ERK MAPK Cascade as Monitored by Fluorescent Probes

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/24427523

12 December 2020

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inferred from PubMed ID database lookup

Neurofibromatosis: the role of guanosine triphosphatase activating proteins in sensory neuron function

1 reference

https://pubmed.ncbi.nlm.nih.gov/24427523

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inferred from PubMed ID database lookup

Time-dependent sensitivity analysis of biological networks: coupled MAPK and PI3K signal transduction pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/24427523

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Neurofibromatosis pain is in the membrane. Focus on "sensory neurons from Nf1 haploinsufficient mice exhibit increased excitability"

1 reference

https://pubmed.ncbi.nlm.nih.gov/24427523

12 December 2020

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Identifiers

10.1098/RSFS.2012.0071

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

ResearchGate publication ID

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