(Q40191686)

18 September 2017

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title

Somatic cell fusion as a source of genetic rearrangement leading to metastatic variants (English)

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18 September 2017

L Larizza

1

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PubMed ID

6388823

18 September 2017

V Schirrmacher

series ordinal

2

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18 September 2017

1 January 1984

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Cancer and Metastasis Reviews

18 September 2017

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18 September 2017

3

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18 September 2017

193-222

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18 September 2017

3

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https://scigraph.springernature.com/pub.10.1007/bf00048385

18 September 2017

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cites work

The origin of metastatic heterogeneity in tumors

1 reference

https://api.crossref.org/works/10.1007%2FBF00048385

Induction of tumor cell rejection in the low responsive YAC-lymphoma strain A host combination by immunization with somatic cell hybrids

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00048385

Response of Syngeneic Murine Lymphomata to Immunotherapy in Relation to the Antigenicity of the Tumour

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00048385

Mutation at Autosomal Loci of Chinese Hamster Ovary Cells: Involvement of a High-Frequency Event Silencing Two Linked Alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00048385

Chromosomal rearrangement and carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00048385

Single-Copy and Amplified CAD Genes in Syrian Hamster Chromosomes Localized by a Highly Sensitive Method for In Situ Hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00048385

Evolution of chromosomal regions containing transfected and amplified dihydrofolate reductase sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00048385

Transcripts from the Cellular Homologs of Retroviral Oncogenes: Distribution Among Chicken Tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF00048385

Mouse c-myc oncogene is located on chromosome 15 and translocated to chromosome 12 in plasmacytomas

21 January 2018

1 reference

12 December 2020

Microcell-mediated transfer of murine chromosomes into mouse, Chinese hamster, and human somatic cells

1 reference

12 December 2020

Antigenic variation in cancer metastasis: immune escape versus immune control

1 reference

12 December 2020

Arrest and metastasis of blood-borne tumor cells are modified by fusion of plasma membrane vesicles from highly metastatic cells

1 reference

12 December 2020

Genotypic and phenotypic evolution of a murine tumor during its progression in vivo toward metastasis

1 reference

12 December 2020

Translocations among antibody genes in human cancer

1 reference

12 December 2020

Generation of phenotypic diversity and progression in metastatic tumor cells

1 reference

12 December 2020

Transforming genes of human bladder and lung carcinoma cell lines are homologous to the ras genes of Harvey and Kirsten sarcoma viruses

1 reference

12 December 2020

Some thoughts about genetics, differentiation, and malignancy

1 reference

12 December 2020

Endomitotic reduplication mechanisms in ascites tumors of the mouse

1 reference

12 December 2020

Chromosomal location of human kappa and lambda immunoglobulin light chain constant region genes

1 reference

12 December 2020

Increasing metastatic potential is associated with increasing genetic instability of clones isolated from murine neoplasms

1 reference

12 December 2020

A direct demonstration of somatically paired heterochromatin of human chromosomes

1 reference

12 December 2020

Supermelanotic hybrids derived from mouse melanomas and normal mouse cells

1 reference

12 December 2020

The use of cell fusion to analyse factors involved in tumour cell metastasis

1 reference

12 December 2020

Suppression of tumorigenicity in somatic cell hybrids. II. Human chromosomes implicated as suppressors of tumorigenicity in hybrids with Chinese hamster ovary cells.

1 reference

12 December 2020

Analysis of two divergent rat genomic clones homologous to the transforming gene of Harvey murine sarcoma virus

1 reference

12 December 2020

Genetic control of tumorigenicity in interspecific mammalian cell hybrids

1 reference

12 December 2020

Somatic cell mating and segregation in chimeric frogs

1 reference

12 December 2020

The mechanisms of endoreduplication

1 reference

12 December 2020

Specific chromosomal translocations and the genesis of B-cell-derived tumors in mice and men.

1 reference

12 December 2020

Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells

1 reference

12 December 2020

The pathogenesis of cancer metastasis

1 reference

12 December 2020

Suppression of the transformed phenotype of hepatoma cells after hybridization with normal diploid fibroblasts

1 reference

12 December 2020

Segregation of recessive phenotypes in somatic cell hybrids: role of mitotic recombination, gene inactivation, and chromosome nondisjunction

1 reference

12 December 2020

Human and mouse cellular myc protooncogenes reside on chromosomes involved in numerical and structural aberrations in cancer

1 reference

12 December 2020

Inheritance of immunogenicity and metastatic potential in murine cell hybrids from the T-lymphoma ESb08 and normal spleen lymphocytes

1 reference

12 December 2020

The use of drug-resistant markers to study the hybridization of mouse fibroblasts.

1 reference

12 December 2020

A metastatic malignant melanoma with 24 chromosomes

1 reference

12 December 2020

Proof of in vivo fusion of murine tumor cells with host cells by universal fusers

1 reference

12 December 2020

The role of gene dosage and genetic transpositions in carcinogenesis

1 reference

12 December 2020

Transforming activity of DNA of chemically transformed and normal cells

1 reference

12 December 2020

A Transforming ras Gene in Tumorigenic Guinea Pig Cell Lines Initiated by Diverse Chemical Carcinogens

1 reference

12 December 2020

Chromosomal changes associated with progression of the Dunning R-3327 rat prostatic adenocarcinoma system

1 reference

12 December 2020

Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma

1 reference

12 December 2020

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1 reference

12 December 2020

Chromosomal localization of human cellular homologues of two viral oncogenes.

1 reference

12 December 2020

Stage-specific transforming genes of human and mouse B- and T-lymphocyte neoplasms

1 reference

12 December 2020

Double minutes and homogeneously staining regions: gene amplification in mammalian cells

1 reference

12 December 2020

Transposition and amplification of oncogene-related sequences in human neuroblastomas

1 reference

12 December 2020

Reversible inactivation of autosomal alleles in Chinese hamster cells

1 reference

12 December 2020

Genetics of somatic mammalian cells. X. Complementation analysis of glycine-requiring mutants

1 reference

12 December 2020

Tumor metastases and cell-mediated immunity in a model system in DBA/2 mice. I. Tumor invasiveness in vitro and metastasis formation in vivo

1 reference

12 December 2020

The Sequential Analysis of Cancer Development

1 reference

12 December 2020

Activation of related transforming genes in mouse and human mammary carcinomas

1 reference

12 December 2020

Clonal origin of human tumors

1 reference

12 December 2020

Nonimmunogenic radiation-induced lymphoma: immunity induction by a somatic cell hybrid

1 reference

12 December 2020

Expression of recessive Aprt- mutations in mouse CAK cells resulting from chromosome loss and duplication

1 reference

12 December 2020

Segregation studies in CHO hybrid cells: I. Spontaneous and mutagen-induced segregation events of two recessive drug-resistant loci

1 reference

12 December 2020

Neoplastic transformation of human diploid cells in vitro after chemical carcinogen treatment

1 reference

12 December 2020

Onc gene amplification in promyelocytic leukaemia cell line HL-60 and primary leukaemic cells of the same patient

1 reference

12 December 2020

Assignment of three human genes to chromosomes (LDH-A to 11, TK to 17, and IDH to 20) and evidence for translocation between human and mouse chromosomes in somatic cell hybrids (thymidine kinase-lactate dehydrogenase A-isocitrate dehydrogenase-C-11,

1 reference

12 December 2020

Hybrid cells in solid tumors

1 reference

12 December 2020

Cellular Oncogenes and Multistep Carcinogenesis

1 reference

12 December 2020

Metastatic clones selected from an RSV-induced mouse sarcoma share a common marker chromosome.

1 reference

12 December 2020

Linkage analyses of murine immunoglobulin heavy chain and serum prealbumin genes establish their location on chromosome 12 proximal to the T (5;12) 31H breakpoint in band 12F1.

1 reference

12 December 2020

Localization of human immunoglobulin kappa light chain variable region genes to the short arm of chromosome 2 by in situ hybridization.

1 reference

12 December 2020

Induction of immortality is an early event in malignant transformation of mammalian cells by carcinogens.

1 reference

12 December 2020

Characterization of stable spontaneous metastatic variant lines of RSV-transformed mouse fibroblasts.

1 reference

12 December 2020

Karyotypic progression in human tumors

1 reference

12 December 2020

Mutation Caused by Human Phagocytes

1 reference

12 December 2020

DNA rearrangement and altered RNA expression of the c-myb oncogene in mouse plasmacytoid lymphosarcomas

1 reference

12 December 2020

Growth in vitro of tumour cell x fibroblast hybrids in which malignancy is suppressed

1 reference

12 December 2020

Expression of transformation markers and suppression of tumorigenicity in human cell hybrids

1 reference

12 December 2020

Limited lifespan in somatic cell hybrids and cybrids.

1 reference

12 December 2020

Identification of transforming gene in two human sarcoma cell lines as a new member of the ras gene family located on chromosome 1.

1 reference

12 December 2020

Amplified C lambda and c-abl genes are on the same marker chromosome in K562 leukemia cells

1 reference

12 December 2020

Homology between an endogenous viral LTR and sequences inserted in an activated cellular oncogene

1 reference

12 December 2020

In vivo Hybridisation of Cultured Melanoma Cells and Isogenic Normal Mouse Cells

1 reference

12 December 2020

Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas

1 reference

12 December 2020

Tumorigenicity of simian virus 40-transformed human cells and mouse--human hybrids in nude mice

1 reference

12 December 2020

Genetic manipulation by means of microcell-mediated transfer of normal human chromosomes into recipient mouse cells

1 reference

12 December 2020

Transforming genes of human hematopoietic tumors: frequent detection of ras-related oncogenes whose activation appears to be independent of tumor phenotype

1 reference

12 December 2020

Association of amplified oncogene c-myc with an abnormally banded chromosome 8 in a human leukaemia cell line.

1 reference

12 December 2020

A novel 6:10 chromosomal translocation in the murine plasmacytoma NS-1.

1 reference

12 December 2020

High-grade tumor-specific immunity induced by L1210 leukemia variants obtained from the culture of L1210 cells fused with Lesch-Nyhan fibroblasts

1 reference

12 December 2020

Studies on transformation markers and tumorigenicity in segregant clones from a human hybrid line

1 reference

12 December 2020

Tumorigenicity of cells transformed by Simian virus 40 and of hybrids between such cells and normal diploid cells

1 reference

12 December 2020

Two human c-onc genes are located on the long arm of chromosome 8.

1 reference

12 December 2020

Human immunoglobulin heavy chain genes map to a region of translocations in malignant B lymphocytes

1 reference

12 December 2020

Studies of multipolar mitoses in euploid tissue cultures. II. Somatic segregation of the sex chromosomes.

1 reference

12 December 2020

Identification of the constant chromosome regions involved in human hematologic malignant disease

1 reference

12 December 2020

Possible epigenetic mechanisms of tumor progression: induction of high-frequency heritable but phenotypically unstable changes in the tumorigenic and metastatic properties of tumor cell populations by 5-azacytidine treatment

1 reference

12 December 2020

Double-minutes--a chromosomal aberration in Rous sarcomas in mice

1 reference

12 December 2020

Independent expression of chemical carcinogen-induced phenotypic properties frequently associated with the neoplastic state in a cultured guinea pig cell line.

1 reference

12 December 2020

A cellular oncogene (c-Ki-ras) is amplified, overexpressed and located within karyotypic abnormalities in mouse adrenocortical tumour cells

1 reference

12 December 2020

A novel chromosome abnormality in human neuroblastoma and antifolate-resistant Chinese hamster cell lives in culture

1 reference

12 December 2020

The chromosomal basis of human neoplasia.

1 reference

12 December 2020

Suppression of the transformed phenotype in somatic cell hybrids

1 reference

12 December 2020

Avian leukosis virus-induced tumors have common proviral integration sites and synthesize discrete new RNAs: oncogenesis by promoter insertion

1 reference

12 December 2020

Asynchronous DNA synthesis and asynchronous mitosis in multinuclear ovarian cancer cells

1 reference

12 December 2020

A new chromosome type replacing the double minutes in a mouse tumor

1 reference

12 December 2020

Amplification and expression of the c-myc oncogene in human lung cancer cell lines

1 reference

12 December 2020

Mapping of human chromosomal regions related to neoplasia: Evidence from chromosomes 1 and 17

1 reference

12 December 2020

Evidence for the clonal origin of spontaneous metastases

1 reference

12 December 2020

Metaphase chromosome anomaly: association with drug resistance and cell-specific products

1 reference

12 December 2020

Relevance of spontaneous in vivo tumor-host cell fusion to tumor progression and metastasis evaluated using a series of lectin-resistant mutant tumor sublines.

1 reference

12 December 2020

In vitro growth characteristics associated with benign and metastatic variants of tumor cells

1 reference

12 December 2020

Suppression of tumorigenicity in hybrids of tumorigenic Chinese hamster cells and diploid mouse fibroblasts: dependence on the presence of at least three different mouse chromosomes and independence of hamster genome dosage

1 reference

12 December 2020

Specific chromosome loss associated with the expression of tumorigenicity in human cell hybrids

1 reference

12 December 2020

Fusion of tumour cells with host cells

1 reference

12 December 2020

Spontaneous fusion in vivo between normal host and tumor cells: possible contribution to tumor progression and metastasis studied with a lectin-resistant mutant tumor

1 reference

12 December 2020

Amplification of endogenous myc-related DNA sequences in a human myeloid leukaemia cell line

1 reference

12 December 2020

Evidence for the recessive nature of cellular immortality

1 reference

12 December 2020

Rearrangement and amplification of c-abl sequences in the human chronic myelogenous leukemia cell line K-562

1 reference

12 December 2020

A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

1 reference

12 December 2020

Different expression of Lyt differentiation antigens and cell surface glycoproteins by a murine T lymphoma line and its highly metastatic variant

1 reference

12 December 2020

Spontaneous fusion between Ehrlich ascites tumor cells and host cells in vivo: kinetics of hybridization, and concurrent changes in the histocompatiblity profile of the tumor after propagation in different host strains

1 reference

12 December 2020

Double minutes in human tumor cells

1 reference

12 December 2020

Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells

1 reference

12 December 2020

Chromosome changes in 6-TG-resistant mutant strains derived from a karyotypically stable human line, C32.

1 reference

12 December 2020

Genetic analysis of tumorigenesis. VIII. Suppression of SV40 transformation in cell hybrids and cytoplasmic transferants

1 reference

12 December 2020

Lymphoma cell-mediated degradation of sulfated proteoglycans in the subendothelial extracellular matrix: relationship to tumor cell metastasis

1 reference

12 December 2020

The formation and properties of macrophage polykaryons (inflammatory giant cells)

1 reference

12 December 2020

Evidence for the progressive nature of neoplastic transformation in vitro

1 reference

12 December 2020

Metastatic variants are generated spontaneously at a high rate in mouse KHT tumor

1 reference

12 December 2020

Double Minute Chromosomes and the Homogeneously Staining Regions in Chromosomes of a Human Neuroblastoma Cell Line

1 reference

12 December 2020

Selection of tumor-host cell hybrids from polyoma virus- and methylcholanthrene-induced sarcomas

1 reference

12 December 2020

Consequences of myc invasion of immunoglobulin loci: facts and speculation

1 reference

12 December 2020

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1 reference

12 December 2020

In vivo hybridisation of human tumour and normal hamster cells.

1 reference

12 December 2020

Fusion of DNA region to murine immunoglobulin heavy chain locus corresponds to plasmacytoma-associated chromosome translocation

1 reference

12 December 2020

Nonmetastatic tumor cells acquire metastatic properties following somatic hybridization with normal cells

1 reference

12 December 2020

Fibroblast immortality is a prerequisite for transformation by EJ c-Ha-ras oncogene

1 reference

12 December 2020

Suppression of tumorigenicity

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12 December 2020

Assignment of genes for immunoglobulin kappa and heavy chains to chromosomes 6 and 12 in mouse

1 reference

12 December 2020

Suggestive evidence that the highly metastatic variant ESb of the T-cell lymphoma Eb is derived from spontaneous fusion with a host macrophage.

1 reference

12 December 2020

Gene-amplification model of carcinogenesis

1 reference

12 December 2020

Heterochromatin polymorphism and human cancer

1 reference

12 December 2020

Replicative potentials of various fusion products between WI-38 and SV40 transformed WI-38 cells and their components

1 reference

12 December 2020

Genetic analysis of tumorigenesis: I. Expression of tumor-forming ability in hamster hybrid cell lines

1 reference

12 December 2020

Mechanism of activation of a human oncogene

1 reference

12 December 2020

Expression of transformation in cell hybrids. I. Isolation and application of density-inhibited Balb/3T3 cells deficient in hypoxanthine phosphoribosyltransferase and resistant to ouabain

1 reference

12 December 2020

Human cell hybrids: analysis of transformation and tumorigenicity

1 reference

12 December 2020

Cytogenetic changes during tumor progression towards invasion, metastasis and immune escape in the Eb/ESb model system

1 reference

12 December 2020

Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus

1 reference

12 December 2020

Suppression of malignancy in human cancer cells: issues and challenges

1 reference

12 December 2020

Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts

1 reference

12 December 2020

Analysis of malignancy in human cells: malignant and transformed phenotypes are under separate genetic control

1 reference

12 December 2020

Metastatic properties conferred on nonmetastatic tumors by hybridization of spleen B-lymphocytes with plasmacytoma cells

1 reference

12 December 2020

Chromosome loss is responsible for segregation at theHPRT locus in Chinese hamster cell hybrids

1 reference

12 December 2020

Correlation of patterns of anchorage-independent growth with in vivo behavior of cells from a murine fibrosarcoma

1 reference

12 December 2020

DNA Methylation and Gene Function

1 reference

12 December 2020

Premature chromosome condensation in carcinoma of the bladder: presumptive evidence for fusion of normal and malignant cells

1 reference

12 December 2020

Parasexual Cycle in Cultivated Human Somatic Cells

1 reference

12 December 2020

Genetic instability coupled to clonal selection as a mechanism for tumor progression in the Dunning R-3327 rat prostatic adenocarcinoma system

1 reference

12 December 2020

Passage of phenotypes of chemically transformed cells via transfection of DNA and chromatin

1 reference

12 December 2020

Tumor x host cell hybrids in the mouse: chromosomes from the normal cell parent maintained in malignant hybrid tumors

1 reference

12 December 2020

Studies on a human melanoma x hamster hybrid line selected by metastasis

1 reference

12 December 2020

Lymphoma development in mice and humans: diversity of initiation is followed by convergent cytogenetic evolution

1 reference

12 December 2020

Expression of transformation in cell hybrids. II. Nonsuppression of the transformed phenotype in hybrids between a chemically transformed and nontransformed derivatives of Balb/3T3

1 reference

12 December 2020

In vivo human-hamster somatic cell fusion indicated by glucose 6-phosphate dehydrogenase and lactate dehydrogenase profiles

1 reference

12 December 2020

Localization of the c-abl oncogene adjacent to a translocation break point in chronic myelocytic leukaemia

1 reference

12 December 2020

Properties of a Normal Mouse Cell DNA Sequence (sarc) Homologous to the src Sequence of Moloney Sarcoma Virus

1 reference

12 December 2020

Continuous cultures of fused cells secreting antibody of predefined specificity

1 reference

12 December 2020

Complementation of the tumorigenic phenotype in human cell hybrids

1 reference

12 December 2020

Cellular oncogenes and retroviruses

1 reference

12 December 2020

Suppression of tumorigenicity in somatic cell hybrids. I. Suppression and reexpression of tumorigenicity in diploid human X D98AH2 hybrids and independent segregation of tumorigenicity from other cell phenotypes.

1 reference

12 December 2020

The analysis of malignancy by cell fusion. IX. Re-examination and clarification of the cytogenetic problem

1 reference

12 December 2020

The origin of human cancers

1 reference

12 December 2020

The role of chromosome 15 in murine leukemogenesis. I. Contrasting behavior of the tumor vs. normal parent-derived chromosomes No. 15 in somatic hybrids of varying tumorigenicity.

1 reference

12 December 2020

Premature chromosome condensation in human leukemia

1 reference

12 December 2020

Induced chromosome variation in cultured cell populations

1 reference

12 December 2020

Cancer genes in cell hybrids

1 reference

12 December 2020

Non-mendelian segregation in hybrids between chinese hamster cells

1 reference

12 December 2020

Random segretation of multiple genetic markers from CHO-CHO hybrids: evidence for random distribution of functional hemizygosity in the genome

1 reference

12 December 2020

Evolution of tumor cell heterogeneity during progressive growth of individual lung metastases

1 reference

12 December 2020

The clonal evolution of tumor cell populations

1 reference

12 December 2020

Oncogenes in human tumor cell lines: molecular cloning of a transforming gene from human bladder carcinoma cells

1 reference

12 December 2020

Abnormalities of chromosome no. 1: two cases with lymphocytic lymphomas

1 reference

12 December 2020

Tumor-host cell hybrids in radiochimeras

1 reference

12 December 2020

The Biology of Cancer Invasion and Metastasis

1 reference

12 December 2020

Role of heterochromatin variation in the instability of a marker chromosome during tumor progression

1 reference

12 December 2020

Activation of a translocated human c-myc gene by an enhancer in the immunoglobulin heavy-chain locus.

1 reference

12 December 2020

Tumor metastases and cell-mediated immunity in a model system in DBA/2 mice.: Iv. Antigenic differences between a metastasizing variant and the parental tumor line revealed by cytotoxic T lymphocytes

1 reference

12 December 2020

Chromosome-wide event accompanies the expression of recessive mutations in tetraploid cells

1 reference

12 December 2020

The HL-60 transforming sequence: a ras oncogene coexisting with altered myc genes in hematopoietic tumors

1 reference

12 December 2020

Onco gen: Human oncogene locations and chromosome aberrations

1 reference

12 December 2020

Tumor-host cell hybrids in radiochimeras reconstituted with bone marrow and thymus grafts

1 reference

12 December 2020

Expression of SV40 T antigen in finite life-span hybrids of normal and SV40-transformed fibroblasts

1 reference

12 December 2020

Mutation and cancer: a model for human carcinogenesis

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00048385

1 reference

PubMed ID

6388823

Dimensions Publication ID

18 September 2017

0 references

1 reference

PubMed ID

6388823