(Q40197189)

18 September 2017

title

Effective suicide gene therapy for leukemia in a model of insertional oncogenesis in mice (English)

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18 September 2017

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6

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18 September 2017

Martina Blumenthal

1

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18 September 2017

Dianne Skelton

2

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18 September 2017

Karen A Pepper

3

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18 September 2017

Thomas Jahn

4

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18 September 2017

Emily Methangkool

5

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18 September 2017

publication date

1 January 2007

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18 September 2017

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18 September 2017

volume

15

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18 September 2017

issue

1

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18 September 2017

page(s)

183-192

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Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy

18 September 2017

cites work

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LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

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Gene therapy insertional mutagenesis insights

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Occurrence of leukaemia following gene therapy of X-linked SCID.

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Unique risk factors for insertional mutagenesis in a mouse model of XSCID gene therapy

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Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector

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In situ use of suicide genes for therapy of brain tumours

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7 January 2021

In situ gene therapy for prostate cancer

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7 January 2021

HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia

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Administration of herpes simplex-thymidine kinase-expressing donor T cells with a T-cell-depleted allogeneic marrow graft

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Side effects of retroviral gene transfer into hematopoietic stem cells

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T cell transduction and suicide with an enhanced mutant thymidine kinase.

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Molecular mechanism for ganciclovir resistance in human T lymphocytes transduced with retroviral vectors carrying the herpes simplex virus thymidine kinase gene.

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Elimination of the truncated message from the herpes simplex virus thymidine kinase suicide gene

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7 January 2021

Herpes simplex virus resistance to antiviral drugs

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7 January 2021

Tumor cells escape suicide gene therapy by genetic and epigenetic instability

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7 January 2021

Murine leukemia induced by retroviral gene marking

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7 January 2021

Gene therapy: therapeutic gene causing lymphoma

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7 January 2021

Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration

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7 January 2021

Multiple modifications in cis elements of the long terminal repeat of retroviral vectors lead to increased expression and decreased DNA methylation in embryonic carcinoma cells.

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7 January 2021

Increased probability of expression from modified retroviral vectors in embryonal stem cells and embryonal carcinoma cells

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7 January 2021

Consistent, persistent expression from modified retroviral vectors in murine hematopoietic stem cells

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7 January 2021

Role for the adaptor protein Grb10 in the activation of Akt

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7 January 2021

A transient three-plasmid expression system for the production of high titer retroviral vectors

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7 January 2021

Identifiers

DOI

10.1038/SJ.MT.6300015

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18 September 2017

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