(Q40200930)

18 September 2017

Suramin affects coupling of rhodopsin to transducin (English)

1 reference

18 September 2017

1 reference

Nicole Lehmann

1

1 reference

18 September 2017

Gopala Krishna Aradhyam

series ordinal

2

1 reference

18 September 2017

Karim Fahmy

series ordinal

3

1 reference

18 September 2017

language of work or name

English

0 references

publication date

1 February 2002

1 reference

18 September 2017

1 reference

18 September 2017

82

1 reference

18 September 2017

2

1 reference

18 September 2017

793-802

1 reference

Rhodopsin: structural basis of molecular physiology

18 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Activation of rhodopsin: new insights from structural and biochemical studies

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Crystal structure of rhodopsin: A G protein-coupled receptor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Uncovering molecular mechanisms involved in activation of G protein-coupled receptors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

G proteins as drug targets

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Binding of transducin and transducin-derived peptides to rhodopsin studies by attenuated total reflection-Fourier transform infrared difference spectroscopy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Solution structure of acidic fibroblast growth factor bound to 1,3, 6-naphthalenetrisulfonate: a minimal model for the anti-tumoral action of suramins and suradistas

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Gsalpha-selective G protein antagonists

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Molecular origin of continuous dark noise in rod photoreceptors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Inhibition of receptor/G protein coupling by suramin analogues.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Protonation states of membrane-embedded carboxylic acid groups in rhodopsin and metarhodopsin II: a Fourier-transform infrared spectroscopy study of site-directed mutants.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Lipid modifications of trimeric G proteins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

On the molecular origins of thermal noise in vertebrate and invertebrate photoreceptors.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Flow of information in the light-triggered cyclic nucleotide cascade of vision

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Phase II study of suramin plus aminoglutethimide in two cohorts of patients with androgen-independent prostate cancer: simultaneous antiandrogen withdrawal and prior antiandrogen withdrawal

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

A prospective study of suramin-induced peripheral neuropathy

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Tryptophan W207 in transducin T alpha is the fluorescence sensor of the G protein activation switch and is involved in the effector binding

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Differential uncoupling of A1 adenosine and D2 dopamine receptors by suramin and didemethylated suramin (NF037).

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Effects of suramin-related and other clinically therapeutic polyanions on protein kinase C activity.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Structure and function of proteins in G-protein-coupled signal transfer

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Theoretical study of the electrostatically driven step of receptor-G protein recognition

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

G protein-coupled receptors. I. Diversity of receptor-ligand interactions

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Suramin is an active site-directed, reversible, and tight-binding inhibitor of protein-tyrosine phosphatases

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

How do G-proteins stay at the plasma membrane?

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Mapping the suramin-binding sites of human neutrophil elastase: investigation by fluorescence resonance energy transfer and molecular modeling.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Functional interaction of transmembrane helices 3 and 6 in rhodopsin. Replacement of phenylalanine 261 by alanine causes reversion of phenotype of a glycine 121 replacement mutant.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Fourier transform infrared difference spectroscopy of rhodopsin mutants: light activation of rhodopsin causes hydrogen-bonding change in residue aspartic acid-83 during meta II formation.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Activation and depalmitoylation of Gs alpha

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

GTP binding protein: properties and lack of activation by phosphorylated rhodopsin.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Kinetic study on the equilibrium between membrane-bound and free photoreceptor G-protein

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

The effect of activating ligands on the intrinsic fluorescence of guanine nucleotide-binding regulatory proteins

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Differential effects of suramin on the coupling of receptors to individual species of pertussis-toxin-sensitive guanine-nucleotide-binding proteins

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Identification of allosteric antagonists of receptor-guanine nucleotide-binding protein interactions

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Identification of effector-activating residues of Gs alpha

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Intrinsic biophysical monitors of transducin activation: fluorescence, UV-visible spectroscopy, light scattering, and evanescent field techniques.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

Molecular determinants of the reversible membrane anchorage of the G-protein transducin.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1301888

GTP hydrolysis by purified alpha-subunit of transducin and its complex with the cyclic GMP phosphodiesterase inhibitor

20 August 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2802%2975441-6

Suramin inhibition of growth factor receptor binding and mitogenicity in AKR-2B cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2802%2975441-6

Phase II trial of suramin in patients with metastatic renal cell carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2802%2975441-6

Light-dependent transducin activation by an ultraviolet-absorbing rhodopsin mutant

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2802%2975441-6

A mutant rhodopsin photoproduct with a protonated Schiff base displays an active-state conformation: a Fourier-transform infrared spectroscopy study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2802%2975441-6

Theoretical study of the electrostatically driven step of receptor-G protein recognition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2802%2975441-6

Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2802%2975441-6

Antiangiogenic and antiproliferative activity of suramin analogues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2802%2975441-6

Ocular symptoms and signs associated with suramin sodium treatment for metastatic cancer of the prostate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2802%2975441-6

Identification of glutamic acid 113 as the Schiff base proton acceptor in the metarhodopsin II photointermediate of rhodopsin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2802%2975441-6

Light- and GTP-regulated interaction of GTPase and other proteins with bovine photoreceptor membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2802%2975441-6

Suramin in non-small cell lung cancer and advanced breast cancer. Two parallel phase II studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2802%2975441-6

Resonance Raman spectroscopy of rhodopsin in retinal disk membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2802%2975441-6

Modulation of the GTPase activity of transducin. Kinetic studies of reconstituted systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2802%2975441-6

8 Preparation of retinal rod outer segments

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2802%2975441-6

Influence of the location of tryptophanyl residues in proteins on their photosensitivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2802%2975441-6

A site on rod G protein alpha subunit that mediates effector activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2802%2975441-6

Novel competitive antagonists for P2 purinoceptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2802%2975441-6

Stereochemistry of the guanyl nucleotide binding site of transducin probed by phosphorothioate analogues of GTP and GDP

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2802%2975441-6

Characterization of the mutant visual pigment responsible for congenital night blindness: a biochemical and Fourier-transform infrared spectroscopy study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-3495%2802%2975441-6

Characterization of interactions between transducin alpha/beta gamma-subunits and lipid membranes

7 January 2021

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11806921

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Antiproliferative and angiostatic activity of suramin analogues

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11806921

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Suramin analogues as subtype-selective G protein inhibitors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11806921

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/S0006-3495(02)75441-6

1 reference

18 September 2017

1 reference

18 September 2017

PubMed publication ID

11806921

1 reference