(Q40202626)

4 March 2018

title

Hypoxia inhibits TRAIL-induced tumor cell apoptosis: involvement of lysosomal cathepsins (English)

1 reference

4 March 2018

1 reference

Nagathihalli S Nagaraj

series ordinal

1

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4 March 2018

Nadarajah Vigneswaran

series ordinal

2

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4 March 2018

Wolfgang Zacharias

series ordinal

3

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4 March 2018

publication date

1 January 2007

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4 March 2018

published in

Apoptosis

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4 March 2018

volume

12

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4 March 2018

issue

1

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4 March 2018

page(s)

125-139

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4 March 2018

https://scigraph.springernature.com/pub.10.1007/s10495-006-0490-1

exact match

0 references

cites work

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Overexpression of both catalytically active and -inactive cathepsin D by cancer cells enhances apoptosis-dependent chemo-sensitivity

17 June 2018

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Modulation of TRAIL-induced tumor cell apoptosis in a hypoxic environment

17 June 2018

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Lysosomal membrane permeabilization during apoptosis--involvement of Bax?

17 June 2018

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Hypoxia alters cathepsin B / inhibitor profiles in oral carcinoma cell lines

17 June 2018

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Cathepsin D: newly discovered functions of a long-standing aspartic protease in cancer and apoptosis

17 June 2018

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17 June 2018

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Cathepsin B promotes both motility and invasiveness of oral carcinoma cells.

17 June 2018

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Apoptosis signaling in tumor therapy

17 June 2018

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Hypoxia-mediated apoptosis in oral carcinoma cells occurs via two independent pathways

17 June 2018

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IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms

17 June 2018

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Hypoxia inhibits tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by blocking Bax translocation

17 June 2018

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17 June 2018

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Targeting hypoxia tolerance in cancer

17 June 2018

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Influence of hypoxia on TRAIL-induced apoptosis in tumor cells

17 June 2018

1 reference

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Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins

17 June 2018

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Cathepsin D mediates cytochrome c release and caspase activation in human fibroblast apoptosis induced by staurosporine

17 June 2018

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Destination 'lysosome': a target organelle for tumour cell killing?

17 June 2018

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Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine.

17 June 2018

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Apo2L/TRAIL and its death and decoy receptors

17 June 2018

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The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions

17 June 2018

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Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

17 June 2018

1 reference

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The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5774619

Hypoxia--a key regulatory factor in tumour growth

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5774619

Cellular stress response and apoptosis in cancer therapy.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5774619

Four deaths and a funeral: from caspases to alternative mechanisms.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5774619

The potential of TRAIL for cancer chemotherapy

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5774619

Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5774619

Apoptosis induced by exposure to a low steady-state concentration of H2O2 is a consequence of lysosomal rupture

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5774619

Caspase-8 in apoptosis: the beginning of "the end"?

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5774619

Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5774619

Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5774619

Unraveling the role of proteases in cancer

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5774619

Exocytosis of active cathepsin B enzyme activity at pH 7.0, inhibition and molecular mass

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5774619

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5774619

Photo-oxidative disruption of lysosomal membranes causes apoptosis of cultured human fibroblasts

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5774619

Cell, tissue and organ culture as in vitro models to study the biology of squamous cell carcinomas of the head and neck

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5774619

Cathepsin B mediates TRAIL-induced apoptosis in oral cancer cells.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5774619

Differential susceptibility of metastatic and primary oral cancer cells to TRAIL-induced apoptosis.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5774619

Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5774619

Cathepsin D triggers Bax activation, resulting in selective apoptosis-inducing factor (AIF) relocation in T lymphocytes entering the early commitment phase to apoptosis

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5774619

Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5774619

Hypoxia inhibition of apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5774619

Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5774619

10.1007/S10495-006-0490-1

20 August 2018

Identifiers

DOI

1 reference

4 March 2018

PMC publication ID

5774619

1 reference

4 March 2018

PubMed publication ID

17136492

1 reference

4 March 2018