(Q40203010)

English

HER2 (erbB-2)-targeted effects of the omega-3 polyunsaturated fatty acid, alpha-linolenic acid (ALA; 18:3n-3), in breast cancer cells: the "fat features" of the "Mediterranean diet" as an "anti-HER2 cocktail".

scientific article published on November 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

HER2 (erbB-2)-targeted effects of the omega-3 polyunsaturated fatty acid, alpha-linolenic acid (ALA; 18:3n-3), in breast cancer cells: the "fat features" of the "Mediterranean diet" as an "anti-HER2 cocktail". (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

0 references

Mediterranean diet

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author name string

Javier A Menéndez

1

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Alejandro Vázquez-Martín

2

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Santiago Ropero

3

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Ramón Colomer

4

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Ruth Lupu

5

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

publication date

1 November 2006

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Clinical and Translational Oncology

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

812-820

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

alpha-Linolenic acid content of adipose breast tissue: a host determinant of the risk of early metastasis in breast cancer.

1 reference

https://api.crossref.org/works/10.1007%2FS12094-006-0137-2

21 January 2018

Update on HER-2 as a target for cancer therapy: the ERBB2 promoter and its exploitation for cancer treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary fatty acids regulate the activation status of Her-2/neu (c-erbB-2) oncogene in breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oleic acid, the main monounsaturated fatty acid of olive oil, suppresses Her-2/neu (erbB-2) expression and synergistically enhances the growth inhibitory effects of trastuzumab (Herceptin) in breast cancer cells with Her-2/neu oncogene amplification

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty Acid Regulation of Gene Transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt Is required for antibody-mediated effects on p27, cyclin D1, and antitumor action

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective capability of dietary Zizyphus mistol seed oil, rich in 18:3, n-3, on the development of two murine mammary gland adenocarcinomas with high or low metastatic potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyunsaturated fatty acids and gene expression in mammalian systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of gene expression by fatty acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional regulation of type I receptor tyrosine kinases in the mammary gland

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of gamma-linolenic acid on the transcriptional activity of the Her-2/neu (erbB-2) oncogene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amplification of Her-2/neu gene in Her-2/neu-overexpressing and -nonexpressing breast carcinomas and their synchronous benign, premalignant, and metastatic lesions detected by FISH in archival material

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of dietary alpha-linolenic acid on growth, metastasis, fatty acid profile and prostaglandin production of two murine mammary adenocarcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of n-3 fatty acids on the growth of human breast cancer cellsin vitro: Relationship to peroxides and Vitamin-E

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genomic explanation connecting "Mediterranean diet", olive oil and cancer: oleic acid, the main monounsaturated fatty acid of olive oil, induces formation of inhibitory "PEA3 transcription factor-PEA3 DNA binding site" complexes at the Her-2/neu (

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of dietary perilla oil, soybean oil and safflower oil on 7,12-dimethylbenz[a]anthracene (DMBA) and 1,2-dimethyl-hydrazine (DMH)-induced mammary gland and colon carcinogenesis in female SD rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary flaxseed alters tumor biological markers in postmenopausal breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exogenous supplementation with omega-3 polyunsaturated fatty acid docosahexaenoic acid (DHA; 22:6n-3) synergistically enhances taxane cytotoxicity and downregulates Her-2/neu (c-erbB-2) oncogene expression in human breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted therapy in breast cancer: the HER-2/neu gene and protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low alpha-linolenic acid content of adipose breast tissue is associated with an increased risk of breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH 3T3 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of a high-linoleate and a high-alpha-linolenate diet on spontaneous mammary tumourigenesis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neu oncogene encodes an epidermal growth factor receptor-related protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of the c-erbB-2 gene enhanced intrinsic metastasis potential in human breast cancer cells without increasing their transformation abilities

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Humanization of an anti-p185HER2 antibody for human cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of c-erbB-2/HER2/neu in breast cancer progression and metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Her-2/neu gene amplification in ductal carcinoma in situ of the breast.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Re: Effect of gamma-linolenic acid on the transcriptional activity of the Her-2/neu (erbB-2) oncogene

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The HER-2/neu oncogene in breast cancer: prognostic factor, predictive factor, and target for therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diet, cancer, and the lipidome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17134970

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12094-006-0137-2

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

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