(Q40203702)

English

Increasing uncoupling protein-2 in pancreatic beta cells does not alter glucose-induced insulin secretion but decreases production of reactive oxygen species.

scientific article published on 28 November 2006

In more languages

default values for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17131143%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

Increasing uncoupling protein-2 in pancreatic beta cells does not alter glucose-induced insulin secretion but decreases production of reactive oxygen species (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17131143%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

1 reference

based on heuristic

inferred from title

reactive oxygen species

1 reference

based on heuristic

inferred from title

insulin secretion involved in cellular response to glucose stimulus

1 reference

based on heuristic

inferred from title

Pedro Luis Herrera

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17131143%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

author name string

N Produit-Zengaffinen

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17131143%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

N Davis-Lameloise

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17131143%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

H Perreten

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17131143%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

D Bécard

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17131143%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

A Gjinovci

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17131143%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

P A Keller

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17131143%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

C B Wollheim

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17131143%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

P Muzzin

9

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17131143%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

F Assimacopoulos-Jeannet

10

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17131143%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

publication date

28 November 2006

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17131143%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17131143%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

50

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17131143%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17131143%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

84-93

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17131143%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

Uncoupling proteins and thermoregulation

1 reference

https://api.crossref.org/works/10.1007%2FS00125-006-0499-6

21 January 2018

Induction of uncoupling protein 2 mRNA in beta-cells is stimulated by oxidation of fatty acids but not by nutrient oversupply

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose Sensitivity and Metabolism-Secretion Coupling Studied during Two-Year Continuous Culture in INS-1E Insulinoma Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superoxide activates mitochondrial uncoupling proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PPAR-gamma overexpression selectively suppresses insulin secretory capacity in isolated pancreatic islets through induction of UCP-2 protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased uncoupling protein-2 levels in beta-cells are associated with impaired glucose-stimulated insulin secretion: mechanism of action

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide nucleotide transhydrogenase: a key role in insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of NF-kappaB by extracellular matrix is involved in spreading and glucose-stimulated insulin secretion of pancreatic beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uncoupling protein 2 knockout mice have enhanced insulin secretory capacity after a high-fat diet

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PPARalpha suppresses insulin secretion and induces UCP2 in insulinoma cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor alpha (PPARalpha) potentiates, whereas PPARgamma attenuates, glucose-stimulated insulin secretion in pancreatic beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear factor-{kappa}B activity in {beta}-cells is required for glucose-stimulated insulin secretion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose induces and leptin decreases expression of uncoupling protein-2 mRNA in human islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiation between glucose-induced desensitization of insulin secretion and beta-cell exhaustion in the HIT-T15 cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uncoupling protein-2 overexpression inhibits mitochondrial death pathway in cardiomyocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistent nuclear factor-kappa B activation in Ucp2-/- mice leads to enhanced nitric oxide and inflammatory cytokine production

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uncoupling proteins: current status and therapeutic prospects

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triggering and amplifying pathways of regulation of insulin secretion by glucose

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for uncoupling protein-2 as a regulator of mitochondrial hydrogen peroxide generation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of adenoviral overexpression of uncoupling protein-2 and -3 on mitochondrial respiration in insulinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection of insulin-producing RINm5F cells against cytokine-mediated toxicity through overexpression of antioxidant enzymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of the overexpression of recombinant uncoupling protein 2 on proliferation, migration and plasminogen activator inhibitor 1 expression in human vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free fatty acid-induced beta-cell defects are dependent on uncoupling protein 2 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uncoupling protein 2: a possible link between fatty acid excess and impaired glucose-induced insulin secretion?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of ATP production and uncoupling protein-2 in the insulin secretory defect induced by chronic exposure to high glucose or free fatty acids and effects of peroxisome proliferator-activated receptor-gamma inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the uncoupling protein-2 gene in INS-1 beta-cells by oleic acid.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological levels of mammalian uncoupling protein 2 do not uncouple yeast mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of glucose responsiveness of insulinoma beta-cells by graded overexpression of glucokinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of UCP3 in CHO cells does not cause uncoupling, but controls mitochondrial activity in the presence of glucose

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological increases in uncoupling protein 3 augment fatty acid oxidation and decrease reactive oxygen species production without uncoupling respiration in muscle cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose suppresses superoxide generation in metabolically responsive pancreatic beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyunsaturated fatty acids stimulate hepatic UCP-2 expression via a PPARalpha-mediated pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-chain acyl CoA regulation of protein kinase C and fatty acid potentiation of glucose-stimulated insulin secretion in clonal beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Implication of glutamate in the kinetics of insulin secretion in rat and mouse perfused pancreas

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uncoupling protein 2, in vivo distribution, induction upon oxidative stress, and evidence for translational regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A simple, rapid, and sensitive DNA assay procedure

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bioluminometric assay of ADP and ATP at high ATP/ADP ratios: assay of ADP after enzymatic removal of ATP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17131143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q40203702&oldid=2203494078"