(Q40215417)

English

DNA repair contributes to the drug-resistant phenotype of primary acute myeloid leukaemia cells with FLT3 internal tandem duplications and is reversed by the FLT3 inhibitor PKC412.

scientific article published on 26 October 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

DNA repair contributes to the drug-resistant phenotype of primary acute myeloid leukaemia cells with FLT3 internal tandem duplications and is reversed by the FLT3 inhibitor PKC412. (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

1 reference

based on heuristic

inferred from title

author name string

C H Seedhouse

1

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

H M Hunter

2

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Europe PubMed Central

PubMed publication ID

18 September 2017

B Lloyd-Lewis

3

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

A-M Massip

4

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

M Pallis

5

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

G I Carter

6

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

M Grundy

7

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

S Shang

8

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

N H Russell

9

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

publication date

26 October 2006

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Europe PubMed Central

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18 September 2017

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Europe PubMed Central

PubMed publication ID

18 September 2017

20

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PubMed publication ID

18 September 2017

12

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Europe PubMed Central

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18 September 2017

2130-2136

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the Unite

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

Inhibition of mutant FLT3 receptors in leukemia cells by the small molecule tyrosine kinase inhibitor PKC412.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

BCR/ABL regulates mammalian RecA homologs, resulting in drug resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

Characterization of mammalian RAD51 double strand break repair using non-lethal dominant-negative forms.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

DNA repair and recombination factor Rad51 is over-expressed in human pancreatic adenocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

Over-expression of wild-type Rad51 correlates with histological grading of invasive ductal breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

Homologous recombination and cell cycle checkpoints: Rad51 in tumour progression and therapy resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

FLT3-ITD-TKD dual mutants associated with AML confer resistance to FLT3 PTK inhibitors and cytotoxic agents by overexpression of Bcl-x(L).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

Elevated recombination in immortal human cells is mediated by HsRAD51 recombinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

Rad51 overexpression promotes alternative double-strand break repair pathways and genome instability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

In vitro and in vivo potentiation of radiosensitivity of malignant gliomas by antisense inhibition of the RAD51 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

Ribozyme minigene-mediated RAD51 down-regulation increases radiosensitivity of human prostate cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

DNA damage-related RNA expression to assess individual sensitivity to ionizing radiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

Rapid and sensitive minimal residual disease detection in acute leukemia by quantitative real-time RT-PCR exemplified by t(12;21) TEL-AML1 fusion transcript

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

Expression profiling of CD34+ hematopoietic stem/ progenitor cells reveals distinct subtypes of therapy-related acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

Radiation sensitivity, H2AX phosphorylation, and kinetics of repair of DNA strand breaks in irradiated cervical cancer cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

Internal tandem duplications of the FLT3 gene are present in leukemia stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

FLT3 length mutations as marker for follow-up studies in acute myeloid leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

21 January 2018

Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

7 January 2021

based on heuristic

inferred from DOI database lookup

Flow cytometric measurement of phosphorylated STAT5 in AML: lack of specific association with FLT3 internal tandem duplications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2404439

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.LEU.2404439

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Dimensions Publication ID

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

ResearchGate publication ID

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