(Q40216411)

18 September 2017

title

Par6-aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control (English)

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18 September 2017

5

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18 September 2017

Victoria Aranda

1

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18 September 2017

Teresa Haire

2

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18 September 2017

Marissa E Nolan

3

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18 September 2017

Joseph P Calarco

4

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18 September 2017

James P Fawcett

6

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18 September 2017

Tony Pawson

7

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18 September 2017

Senthil K Muthuswamy

8

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18 September 2017

publication date

22 October 2006

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18 September 2017

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18 September 2017

volume

8

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18 September 2017

issue

11

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18 September 2017

page(s)

1235-1245

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Ultrastructural of the bronchial epithelium in chronic inflammation

18 September 2017

cites work

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Cytokines in cancer pathogenesis and cancer therapy

21 January 2018

1 reference

21 January 2018

Origins of cell polarity

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The tight junction: a multifunctional complex

21 January 2018

1 reference

Organization of vesicular trafficking in epithelia

21 January 2018

1 reference

Epithelial polarity and tubulogenesis in vitro.

21 January 2018

1 reference

ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini

21 January 2018

1 reference

Multilayering and loss of apical polarity in MDCK cells transformed with viral K-ras

21 January 2018

1 reference

Oncogenic Raf-1 disrupts epithelial tight junctions via downregulation of occludin

21 January 2018

1 reference

Activation of an inducible c-FosER fusion protein causes loss of epithelial polarity and triggers epithelial-fibroblastoid cell conversion

21 January 2018

1 reference

The estrogen-dependent c-JunER protein causes a reversible loss of mammary epithelial cell polarity involving a destabilization of adherens junctions

21 January 2018

1 reference

Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases

21 January 2018

1 reference

Cdc42-dependent modulation of tight junctions and membrane protein traffic in polarized Madin-Darby canine kidney cells

21 January 2018

1 reference

Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene

21 January 2018

1 reference

Epithelial polarity and proliferation control: links from the Drosophila neoplastic tumor suppressors

21 January 2018

1 reference

Adaptation of core mechanisms to generate cell polarity

21 January 2018

1 reference

Genetic variation in DLG5 is associated with inflammatory bowel disease

21 January 2018

1 reference

ERBB receptors and cancer: the complexity of targeted inhibitors

21 January 2018

1 reference

The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini.

21 January 2018

1 reference

Amplification of the neu/erbB-2 oncogene in a mouse model of mammary tumorigenesis.

21 January 2018

1 reference

Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers

21 January 2018

1 reference

A versatile synthetic dimerizer for the regulation of protein-protein interactions

21 January 2018

1 reference

Cell polarity: Par6, aPKC and cytoskeletal crosstalk

21 January 2018

1 reference

Par proteins: partners in polarization

21 January 2018

1 reference

Apicobasal polarity complexes.

21 January 2018

1 reference

The PAR-aPKC system: lessons in polarity

21 January 2018

1 reference

PAR-6 regulates aPKC activity in a novel way and mediates cell-cell contact-induced formation of the epithelial junctional complex.

21 January 2018

1 reference

Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

21 January 2018

1 reference

Molecular recognition in dimerization between PB1 domains

21 January 2018

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PB1 domain-mediated heterodimerization in NADPH oxidase and signaling complexes of atypical protein kinase C with Par6 and p62

21 January 2018

1 reference

The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin

21 January 2018

1 reference

Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase

21 January 2018

1 reference

Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein

21 January 2018

1 reference

Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cells

21 January 2018

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Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis.

21 January 2018

1 reference

Targeting RAS signalling pathways in cancer therapy

21 January 2018

1 reference

The STATs of cancer--new molecular targets come of age

21 January 2018

1 reference

EGF-ERBB signalling: towards the systems level

21 January 2018

1 reference

Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

21 January 2018

1 reference

Atypical protein kinase C iota is an oncogene in human non-small cell lung cancer

21 January 2018

1 reference

Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer.

21 January 2018

1 reference

A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity

21 January 2018

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Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

21 January 2018

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Second-generation shRNA libraries covering the mouse and human genomes

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Probing tumor phenotypes using stable and regulated synthetic microRNA precursors

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCB1485

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18 September 2017

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