(Q40216944)

18 September 2017

title

Toll-like receptor 4 region Glu24-Lys47 is a site for MD-2 binding: importance of CYS29 and CYS40. (English)

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18 September 2017

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Chiaki Nishitani

1

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18 September 2017

Hiroaki Mitsuzawa

2

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18 September 2017

Hitomi Sano

3

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18 September 2017

Takeyuki Shimizu

4

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18 September 2017

Norio Matsushima

5

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18 September 2017

Yoshio Kuroki

6

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18 September 2017

language of work or name

English

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publication date

20 October 2006

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Journal of Biological Chemistry

18 September 2017

published in

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18 September 2017

volume

281

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18 September 2017

issue

50

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18 September 2017

page(s)

38322-38329

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Phylogenetic perspectives in innate immunity

18 September 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M606904200

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Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction

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Structure and function of lipopolysaccharide binding protein

21 January 2018

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CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein

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MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4

21 January 2018

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

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The amino-terminal region of toll-like receptor 4 is essential for binding to MD-2 and receptor translocation to the cell surface

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M606904200

The Toll-like receptor 4 region Glu24-Pro34 is critical for interaction with MD-2.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M606904200

Interaction of soluble form of recombinant extracellular TLR4 domain with MD-2 enables lipopolysaccharide binding and attenuates TLR4-mediated signaling

21 January 2018

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The extracellular toll-like receptor 2 domain directly binds peptidoglycan derived from Staphylococcus aureus

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M606904200

Extracellular Toll-like receptor 2 region containing Ser40-Ile64 but not Cys30-Ser39 is critical for the recognition of Staphylococcus aureus peptidoglycan

21 January 2018

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Soluble MD-2 activity in plasma from patients with severe sepsis and septic shock

21 January 2018

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Pharmacological inhibition of endotoxin responses is achieved by targeting the TLR4 coreceptor, MD-2.

21 January 2018

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Crystal structure of the platelet glycoprotein Ib(alpha) N-terminal domain reveals an unmasking mechanism for receptor activation

21 January 2018

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The molecular structure of the Toll-like receptor 3 ligand-binding domain.

21 January 2018

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Mapping the protein universe

21 January 2018

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Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain

21 January 2018

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Lipopolysaccharide interaction with cell surface Toll-like receptor 4-MD-2: higher affinity than that with MD-2 or CD14.

21 January 2018

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Crystal structure of human toll-like receptor 3 (TLR3) ectodomain

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M606904200

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18 September 2017

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