(Q40224632)

English

Inhibition of IGF-I receptor in anchorage-independence attenuates GSK-3beta constitutive phosphorylation and compromises growth and survival of medulloblastoma cell lines

scientific article published on 2 October 2006

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scholarly article

1 reference

Europe PubMed Central

18 September 2017

Inhibition of IGF-I receptor in anchorage-independence attenuates GSK-3beta constitutive phosphorylation and compromises growth and survival of medulloblastoma cell lines (English)

1 reference

Europe PubMed Central

18 September 2017

medulloblastoma

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phosphorylation

1 reference

based on heuristic

inferred from title

author name string

K Urbanska

1

1 reference

Europe PubMed Central

18 September 2017

J Trojanek

2

1 reference

Europe PubMed Central

18 September 2017

L Del Valle

3

1 reference

Europe PubMed Central

18 September 2017

M B Eldeen

4

1 reference

Europe PubMed Central

18 September 2017

F Hofmann

5

1 reference

Europe PubMed Central

18 September 2017

C Garcia-Echeverria

6

1 reference

Europe PubMed Central

18 September 2017

K Khalili

7

1 reference

Europe PubMed Central

18 September 2017

K Reiss

8

1 reference

Europe PubMed Central

18 September 2017

language of work or name

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publication date

2 October 2006

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Europe PubMed Central

18 September 2017

1 reference

Europe PubMed Central

18 September 2017

26

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Europe PubMed Central

18 September 2017

16

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Europe PubMed Central

18 September 2017

2308-2317

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Europe PubMed Central

18 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1210018

0 references

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Inhibition of bone-derived insulin-like growth factors by a ligand-specific antibody suppresses the growth of human multiple myeloma in the human adult bone explanted in NOD/SCID mouse

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The IGF-I receptor and cancer

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GSK-3beta inhibition by lithium confers resistance to chemotherapy-induced apoptosis through the repression of CD95 (Fas/APO-1) expression

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Differential induction of cell death in human glioma cell lines by sodium nitroprusside

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Cell adhesion to the extracellular matrix protein fibronectin modulates radiation-dependent G2 phase arrest involving integrin-linked kinase (ILK) and glycogen synthase kinase-3beta (GSK-3beta) in vitro

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Inhibition of glycogen synthase kinase 3beta activity regulates proliferation of cultured cerebellar granule cells.

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Insulin-like growth factor I receptor signaling system in JC virus T antigen-induced primitive neuroectodermal tumors--medulloblastomas.

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Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

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Glycogen Synthase Kinase-3 from Rabbit Skeletal Muscle

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In vivo antitumor activity of NVP-AEW541-A novel, potent, and selective inhibitor of the IGF-IR kinase

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Patched target Igf2 is indispensable for the formation of medulloblastoma and rhabdomyosarcoma.

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Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase.

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Hedgehog signaling in animal development: paradigms and principles

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Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes

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The effects of clozapine on the GSK-3-mediated signaling pathway

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Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors

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Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors.

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Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3.

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Neural precursor cycling at sonic speed: N-Myc pedals, GSK-3 brakes

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Human ubiquitous JCV(CY) T-antigen gene induces brain tumors in experimental animals

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ILKAP regulates ILK signaling and inhibits anchorage-independent growth

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Insulin receptor substrate 1 translocation to the nucleus by the human JC virus T-antigen

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Insulin-like growth factor receptors. Implications for nervous system function

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Biomembrane-permeable and Ribonuclease-resistant siRNA with enhanced activity

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Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis.

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Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice

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Insulin-like growth factor-I receptor - a potential therapeutic target in medulloblastomas.

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Molecular markers of IGF-I-mediated mitogenesis

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Synthetic peptide sequence from the C-terminus of the insulin-like growth factor-I receptor that induces apoptosis and inhibition of tumor growth

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Antitumor activity of the insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 in musculoskeletal tumors.

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The Cdk1 complex plays a prime role in regulating N-myc phosphorylation and turnover in neural precursors.

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Role of the insulin-like growth factor I/insulin receptor substrate 1 axis in Rad51 trafficking and DNA repair by homologous recombination.

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Anti-apoptotic signaling of the IGF-I receptor in fibroblasts following loss of matrix adhesion

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7 January 2021

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10.1038/SJ.ONC.1210018

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Europe PubMed Central

18 September 2017

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1 reference

Europe PubMed Central

18 September 2017

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