(Q40231950)

English

Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements

scientific article published on November 1994

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scholarly article

1 reference

Europe PubMed Central

18 September 2017

Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements (English)

1 reference

Europe PubMed Central

18 September 2017

author name string

T Dalton

1

1 reference

Europe PubMed Central

18 September 2017

R D Palmiter

2

1 reference

Europe PubMed Central

18 September 2017

G K Andrews

3

1 reference

Europe PubMed Central

18 September 2017

publication date

1 November 1994

1 reference

Europe PubMed Central

18 September 2017

Nucleic Acids Research

1 reference

Europe PubMed Central

18 September 2017

22

1 reference

Europe PubMed Central

18 September 2017

5016-5023

1 reference

Europe PubMed Central

18 September 2017

23

1 reference

Europe PubMed Central

18 September 2017

H2O2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Cloned transcription factor MTF-1 activates the mouse metallothionein I promoter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Transcriptional regulation of the rat NAD(P)H:quinone reductase gene. Characterization of a DNA-protein interaction at the antioxidant responsive element and induction by 12-O-tetradecanoylphorbol 13-acetate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Yeast and mammalian metallothioneins functionally substitute for yeast copper-zinc superoxide dismutase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Oxidative metal release from metallothionein via zinc-thiol/disulfide interchange

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Transcriptional regulation of a rat liver glutathione S-transferase Ya subunit gene. Analysis of the antioxidant response element and its activation by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with a constitutively active transcription factor, MTF-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Isolation and characterization of the mouse metallothionein-I gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Induction of mouse metallothionein-I mRNA by bacterial endotoxin is independent of metals and glucocorticoid hormones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

A 12-base-pair DNA motif that is repeated several times in metallothionein gene promoters confers metal regulation to a heterologous gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Regulation, Linkage, and Sequence of Mouse Metallothionein I and II Genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Interleukin 1 regulates human metallothionein gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Structure and tissue-specific expression of the human metallothionein IB gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Metallothionein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Biochemistry of metallothionein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Rat metallothionein-1 structural gene and three pseudogenes, one of which contains 5'-regulatory sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Molecular biology of metallothionein gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Cloning and expression of an avian metallothionein-encoding gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Fine mapping of a mouse metallothionein gene metal response element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Metallothioneins: proteins in search of function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Tissue-specific regulation of zinc metabolism and metallothionein genes by interleukin 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Oxidant stress leads to transcriptional activation of the human heme oxygenase gene in cultured skin fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Interleukin 6 regulates metallothionein gene expression and zinc metabolism in hepatocyte monolayer cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Activation of the oxidative metabolism in human polymorphonuclear neutrophilic granulocytes: the role of immuno-modulating cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Transcriptional regulator of oxidative stress-inducible genes: direct activation by oxidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Role of free radicals and catalytic metal ions in human disease: an overview

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Nuclear factor kappa B: an oxidative stress-responsive transcription factor of eukaryotic cells (a review)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Regulation of human NAD(P)H:quinone oxidoreductase gene. Role of AP1 binding site contained within human antioxidant response element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

22 September 2017

Induction of heme oxygenase: a general response to oxidant stress in cultured mammalian cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

25 September 2017

Characterization of the DNA-binding properties of the early growth response-1 (Egr-1) transcription factor: evidence for modulation by a redox mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

17 June 2018

Structure of mouse metallothionein-I gene and its mRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

17 June 2018

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

17 June 2018

Identification of multiple metal regulatory elements in mouse metallothionein-I promoter by assaying synthetic sequences.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

17 June 2018

The sheep metallothionein gene family. Structure, sequence and evolutionary relationship of five linked genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

17 June 2018

Expression of the haemopexin-transport system in cultured mouse hepatoma cells. Links between haemopexin and iron metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

17 June 2018

Variation in enzymatic transient gene expression assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

17 June 2018

Inhibition of hydroxyl-radical-generated DNA degradation by metallothionein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

17 June 2018

Transcriptional regulation of the rat glutathione S-transferase Ya subunit gene. Characterization of a xenobiotic-responsive element controlling inducible expression by phenolic antioxidants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

17 June 2018

Oxy radicals in endotoxin shock.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

17 June 2018

Automation of a chloramphenicol acetyltransferase assay.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

17 June 2018

Endotoxin induction of murine metallothionein gene expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

17 June 2018

Induction of the heme oxygenase gene in human skin fibroblasts by hydrogen peroxide and UVA (365 nm) radiation: evidence for the involvement of the hydroxyl radical.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

17 June 2018

Metallothionein Mto gene of Drosophila melanogaster: structure and regulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

17 June 2018

Transcriptional regulation of the rat NAD(P)H:quinone reductase gene. Identification of regulatory elements controlling basal level expression and inducible expression by planar aromatic compounds and phenolic antioxidants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

17 June 2018

Induction of metallothionein by diethyl maleate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

17 June 2018

Examination of potential mechanism(s) of metallothionein induction by diethyl maleate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

17 June 2018

Tumor necrosis factor induced oxidative stress in isolated mouse hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=523772

20 August 2018

Regulation of metallothionein gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/7800494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increase in metallothionein produced by chemicals that induce oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/7800494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heme oxygenase induction by CoCl2, Co-protoporphyrin IX, phenylhydrazine, and diamide: Evidence for oxidative stress involvement

1 reference

https://pubmed.ncbi.nlm.nih.gov/7800494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of hepatic metallothionein by nonmetallic compounds associated with acute-phase response in inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7800494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

63 Induction of metallothionein in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/7800494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metallothionein and zinc metabolism in hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7800494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metallothionein gene regulation in the preimplantation rabbit blastocyst

1 reference

https://pubmed.ncbi.nlm.nih.gov/7800494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both near ultraviolet radiation and the oxidizing agent hydrogen peroxide induce a 32-kDa stress protein in normal human skin fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/7800494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional regulation of the mouse metallothionein-I gene by heavy metals

1 reference

https://pubmed.ncbi.nlm.nih.gov/7800494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of hydroxyl radicals from hydrogen peroxide and iron salts by superoxide- and ascorbate-dependent mechanisms: relevance to the pathology of rheumatoid disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/7800494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of hepatic metallothionein by paraquat

1 reference

https://pubmed.ncbi.nlm.nih.gov/7800494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Corticosterone enhances the zinc and interleukin-6-mediated induction of metallothionein in cultured rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7800494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals

1 reference

https://pubmed.ncbi.nlm.nih.gov/7800494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The major late transcription factor binds to and activates the mouse metallothionein I promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/7800494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypochlorous acid mobilizes cellular zinc

1 reference

https://pubmed.ncbi.nlm.nih.gov/7800494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optimized assays for quantifying transient expressions of co-transfected beta-galactosidase and CAT reporter genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7800494

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/NAR/22.23.5016

1 reference

Europe PubMed Central

18 September 2017

1 reference

Europe PubMed Central

18 September 2017

1 reference

Europe PubMed Central

18 September 2017

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