(Q40243986)

English

Lack of glycoprotein 130/signal transducer and activator of transcription 3-mediated signaling in hepatocytes enhances chronic liver injury and fibrosis progression in a model of sclerosing cholangitis

scientific article published on 9 April 2010

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

Lack of glycoprotein 130/signal transducer and activator of transcription 3-mediated signaling in hepatocytes enhances chronic liver injury and fibrosis progression in a model of sclerosing cholangitis (English)

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

ascending cholangitis

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author name string

Werner Plum

1

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

Darjus F Tschaharganeh

2

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

Daniela C Kroy

3

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

Eva Corsten

4

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

Stephanie Erschfeld

5

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

Uta Dierssen

6

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

Hermann Wasmuth

7

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

Christian Trautwein

8

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

Konrad L Streetz

9

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Europe PubMed Central

PMC publication ID

18 September 2017

language of work or name

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publication date

9 April 2010

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Europe PubMed Central

PMC publication ID

18 September 2017

The American Journal of Pathology

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Europe PubMed Central

PMC publication ID

18 September 2017

176

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Europe PubMed Central

PMC publication ID

18 September 2017

5

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

2236-2246

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2861089/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Lymphotoxin-beta receptor signaling regulates hepatic stellate cell function and wound healing in a murine model of chronic liver injury

1 reference

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Bile acid-induced apoptosis in hepatocytes is caspase-6-dependent

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Hepatotoxin-induced changes in the adult murine liver promote MYC-induced tumorigenesis

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Intermediate filament cytoskeleton of the liver in health and disease

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TRAIL mediates liver injury by the innate immune system in the bile duct-ligated mouse

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Oncostatin M gene therapy attenuates liver damage induced by dimethylnitrosamine in rats

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A new xenobiotic-induced mouse model of sclerosing cholangitis and biliary fibrosis

1 reference

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Opposing roles of gp130-mediated STAT-3 and ERK-1/ 2 signaling in liver progenitor cell migration and proliferation

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22 September 2017

Bile acids inhibit interleukin-6 signaling via gp130 receptor-dependent and -independent pathways in rat liver

1 reference

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IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation.

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Hepatic expression of the tumor necrosis factor family member lymphotoxin-beta is regulated by interleukin (IL)-6 and IL-1beta: transcriptional control mechanisms in oval cells and hepatoma cell lines

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Oncostatin M induces an acute phase response but does not modulate the growth or maturation-status of liver progenitor (oval) cells in culture

1 reference

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Oncostatin M inhibits proliferation of rat oval cells, OC15-5, inducing differentiation into hepatocytes

1 reference

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The origin and liver repopulating capacity of murine oval cells

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In vitro interleukin-6 treatment prevents mortality associated with fatty liver transplants in rats

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Defective gp130-mediated signal transducer and activator of transcription (STAT) signaling results in degenerative joint disease, gastrointestinal ulceration, and failure of uterine implantation

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Impaired preneoplastic changes and liver tumor formation in tumor necrosis factor receptor type 1 knockout mice

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The development and compensation of biliary cirrhosis in interleukin-6-deficient mice

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Postnatally induced inactivation of gp130 in mice results in neurological, cardiac, hematopoietic, immunological, hepatic, and pulmonary defects

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Impaired immune and acute-phase responses in interleukin-6-deficient mice.

1 reference

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Molecular dissection of gp130-dependent pathways in hepatocytes during liver regeneration.

1 reference

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Remarkable heterogeneity displayed by oval cells in rat and mouse models of stem cell-mediated liver regeneration.

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20 August 2018

The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury

1 reference

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20 August 2018

Interleukin 6/gp130-dependent pathways are protective during chronic liver diseases

1 reference

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Interleukin-6 protects against Fas-mediated death by establishing a critical level of anti-apoptotic hepatic proteins FLIP, Bcl-2, and Bcl-xL.

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Hepatocyte-specific expression of Cre recombinase

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Gp130 signaling promotes development of acute experimental colitis by facilitating early neutrophil/macrophage recruitment and activation

1 reference

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4 November 2018

Acute obstructive cholangiopathy in interleukin-6 deficient mice: compensation by leukemia inhibitory factor (LIF) suggests importance of gp-130 signaling in the ductular reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/20382701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of gp130 expression in hepatocytes promotes liver injury1 1K.L.S. and T.W. contributed equally to this work

1 reference

https://pubmed.ncbi.nlm.nih.gov/20382701

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2353/AJPATH.2010.090469

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 September 2017

ResearchGate publication ID

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