(Q40249649)

18 September 2017

title

A novel functional role for the highly conserved alpha-subunit KVGFFKR motif distinct from integrin alphaIIbbeta3 activation processes (English)

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18 September 2017

Aylward K

1

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18 September 2017

Meade G

2

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18 September 2017

Ahrens I

3

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18 September 2017

Devocelle M

4

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18 September 2017

Moran N

5

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18 September 2017

publication date

1 August 2006

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Journal of Thrombosis and Haemostasis

18 September 2017

published in

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18 September 2017

volume

4

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18 September 2017

issue

8

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18 September 2017

page(s)

1804-1812

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Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins

18 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

Membrane-mediated structural transitions at the cytoplasmic face during integrin activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

Association of the membrane proximal regions of the alpha and beta subunit cytoplasmic domains constrains an integrin in the inactive state

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

Solution structures of the cytoplasmic tail complex from platelet integrin alpha IIb- and beta 3-subunits

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

Breaking the integrin hinge. A defined structural constraint regulates integrin signaling

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

Integrin cytoplasmic domains mediate inside-out signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

Importance of integrin LFA-1 deactivation for the generation of immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

Identification of a novel calcium-binding protein that interacts with the integrin alphaIIb cytoplasmic domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

Ancient ubiquitous protein 1 binds to the conserved membrane-proximal sequence of the cytoplasmic tail of the integrin alpha subunits that plays a crucial role in the inside-out signaling of alpha IIbbeta 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

Protein phosphatase 1 associates with the integrin alphaIIb subunit and regulates signaling

21 January 2018

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ICln, a novel integrin alphaIIbbeta3-associated protein, functionally regulates platelet activation

21 January 2018

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21 January 2018

1 reference

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Distinct roles for the alpha and beta subunits in the functions of integrin alphaMbeta2

21 January 2018

1 reference

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Evidence for a differential functional regulation of the two beta(3)-integrins alpha(V)beta(3) and alpha(IIb)beta(3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

The beta3 subunit of the integrin alphaIIbbeta3 regulates alphaIIb-mediated outside-in signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

A palmitylated peptide derived from the glycoprotein Ib beta cytoplasmic tail inhibits platelet activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

A sequence within the cytoplasmic tail of GpIIb independently activates platelet aggregation and thromboxane synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

A membrane-distal segment of the integrin alpha IIb cytoplasmic domain regulates integrin activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

Platelet α2β1 integrin activation: contribution of ligand internalization and the α2-cytoplasmic domain

21 January 2018

1 reference

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Two functional active conformations of the integrin {alpha}2{beta}1, depending on activation condition and cell type.

21 January 2018

1 reference

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9-Fluorenylmethoxycarbonyl amino-protecting group

21 January 2018

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Antimicrobial activity of arginine- and tryptophan-rich hexapeptides: the effects of aromatic clusters, D-amino acid substitution and cyclization

21 January 2018

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Noninvasive intracellular delivery of functional peptides and proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

Identification of a functionally important sequence in the cytoplasmic tail of integrin beta 3 by using cell-permeable peptide analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

A high-throughput assay for assessing the cell permeability of combinatorial libraries

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

The engineering of membrane-permeable peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

Calreticulin-independent regulation of the platelet integrin alphaIIbbeta3 by the KVGFFKR alphaIIb-cytoplasmic motif.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

A new functional role of the fibrinogen RGD motif as the molecular switch that selectively triggers integrin alphaIIbbeta3-dependent RhoA activation during cell spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

Suppression of integrin activation by the membrane-distal sequence of the integrin alphaIIb cytoplasmic tail

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2006.02041.X

10.1111/J.1538-7836.2006.02041.X

21 January 2018

Identifiers

DOI

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18 September 2017

1 reference