(Q40252196)

18 September 2017

title

RB silencing compromises the DNA damage-induced G2/M checkpoint and causes deregulated expression of the ECT2 oncogene (English)

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18 September 2017

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Eguchi T

1

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18 September 2017

Takaki T

series ordinal

2

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18 September 2017

Itadani H

series ordinal

3

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18 September 2017

Kotani H

series ordinal

4

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18 September 2017

language of work or name

English

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publication date

24 July 2006

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18 September 2017

number of pages

12

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inferred from page(s)

published in

Oncogene

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18 September 2017

volume

26

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18 September 2017

issue

4

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18 September 2017

page(s)

509-520

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Structural evidence for the authenticity of the human retinoblastoma gene

18 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

21 January 2018

1 reference

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7 January 2021

Inhibition of cyclin-dependent kinase 2 by p21 is necessary for retinoblastoma protein-mediated G1 arrest after gamma-irradiation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

Emerging roles for E2F: Beyond the G1/S transition and DNA replication

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

Amplification of the Ect2 proto-oncogene and over-expression of Ect2 mRNA and protein in nickel compound and methylcholanthrene-transformed 10T1/2 mouse fibroblast cell lines

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

A requirement for Rho and Cdc42 during cytokinesis in Xenopus embryos.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

The regulation of E2F by pRB-family proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

p53 regulation of G(2) checkpoint is retinoblastoma protein dependent

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

Cell cycle-regulated expression of mammalian CDC6 is dependent on E2F.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

The Rab6-binding kinesin, Rab6-KIFL, is required for cytokinesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

Aberrant regulation of survivin by the RB/E2F family of proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

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7 January 2021

Chromosome condensation by a human condensin complex in Xenopus egg extracts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

Accumulation of GTP-bound RhoA during cytokinesis and a critical role of ECT2 in this accumulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

Liver-specific pRB loss results in ectopic cell cycle entry and aberrant ploidy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

Oncogene ect2 is related to regulators of small GTP-binding proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

E2F mediates sustained G2 arrest and down-regulation of Stathmin and AIM-1 expression in response to genotoxic stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

RHO-GTPases and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

Deregulation and mislocalization of the cytokinesis regulator ECT2 activate the Rho signaling pathways leading to malignant transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

Rho exchange factor ECT2 is induced by growth factors and regulates cytokinesis through the N‐terminal cell cycle regulator‐related domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

A Rho-specific exchange factor Ect2 is induced from S to M phases in regenerating mouse liver

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

The RB and p53 pathways in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

CDK inhibitors: positive and negative regulators of G1-phase progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

Human ECT2 is an exchange factor for Rho GTPases, phosphorylated in G2/M phases, and involved in cytokinesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

Role of retinoblastoma tumor suppressor protein in DNA damage response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

Transforming potential of Dbl family proteins correlates with transcription from the cyclin D1 promoter but not with activation of Jun NH2-terminal kinase, p38/Mpk2, serum response factor, or c-Jun

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

Mechanisms of transcriptional regulation by Rb-E2F segregate by biological pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209810

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209810

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Dimensions Publication ID

18 September 2017

1048297991

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1 reference