(Q40256606)

English

Decorin protein core inhibits in vivo cancer growth and metabolism by hindering epidermal growth factor receptor function and triggering apoptosis via caspase-3 activation

scientific article published on 11 July 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Decorin protein core inhibits in vivo cancer growth and metabolism by hindering epidermal growth factor receptor function and triggering apoptosis via caspase-3 activation (English)

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

apoptotic process

1 reference

based on heuristic

inferred from title

Renato V. Iozzo

8

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Europe PubMed Central

PubMed publication ID

18 September 2017

author name string

Daniela G Seidler

1

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Europe PubMed Central

PubMed publication ID

18 September 2017

Silvia Goldoni

2

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Europe PubMed Central

PubMed publication ID

18 September 2017

Christopher Agnew

3

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Christopher Cardi

4

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Mathew L Thakur

5

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Rick T Owens

6

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

David J McQuillan

7

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

language of work or name

0 references

publication date

11 July 2006

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

18 September 2017

281

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Europe PubMed Central

PubMed publication ID

18 September 2017

36

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Europe PubMed Central

PubMed publication ID

18 September 2017

26408-26418

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Europe PubMed Central

PubMed publication ID

18 September 2017

Multiple positive and negative regulators of signaling by the EGF-receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Localization and modulation of ErbB receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

The EGF receptor family as targets for cancer therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

The family of the small leucine-rich proteoglycans: key regulators of matrix assembly and cellular growth

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

The biology of the small leucine-rich proteoglycans. Functional network of interactive proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

De novo decorin gene expression suppresses the malignant phenotype in human colon cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Ectopic expression of decorin protein core causes a generalized growth suppression in neoplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Decorin suppresses tumor cell growth by activating the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Decorin is a biological ligand for the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Decorin binds to a narrow region of the epidermal growth factor (EGF) receptor, partially overlapping but distinct from the EGF-binding epitope

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Decorin-mediated signal transduction in endothelial cells. Involvement of Akt/protein kinase B in up-regulation of p21(WAF1/CIP1) but not p27(KIP1).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Decorin inhibits macrophage colony-stimulating factor proliferation of macrophages and enhances cell survival through induction of p27(Kip1) and p21(Waf1).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Matrix proteoglycans: from molecular design to cellular function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Cooperative action of germ-line mutations in decorin and p53 accelerates lymphoma tumorigenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Suppression of decorin expression and partial induction of anchorage-independent growth by the v-src oncogene in human fibroblasts.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Transcription factor ATF3 partially transforms chick embryo fibroblasts by promoting growth factor-independent proliferation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Down-regulation of the extracellular matrix protein SPARC in vSrc- and vJun-transformed chick embryo fibroblasts contributes to tumor formation in vivo.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Analysis of differentially expressed genes in human hepatocellular carcinoma using suppression subtractive hybridization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Effects of ectopic decorin in modulating intracranial glioma progression in vivo, in a rat syngeneic model

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

In vivo selective and distant killing of cancer cells using adenovirus-mediated decorin gene transfer.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Decorin prevents metastatic spreading of breast cancer.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through alpha2beta1 integrin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Recombinant decorin glycoforms. Purification and structure

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Uniform overexpression and rapid accessibility of alpha5beta1 integrin on blood vessels in tumors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Etoposide: four decades of development of a topoisomerase II inhibitor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Biologically active decorin is a monomer in solution.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

The biology of perlecan: the multifaceted heparan sulphate proteoglycan of basement membranes and pericellular matrices

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Essential contribution of tumor-derived perlecan to epidermal tumor growth and angiogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Molecular targeting of growth factor receptor-bound 2 (Grb2) as an anti-cancer strategy.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Caspases 3 and 7: key mediators of mitochondrial events of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

The Ki-67 protein: from the known and the unknown

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Tyrosine kinase inhibition: an approach to drug development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

A physiologic three-dimensional cell culture system to investigate the role of decorin in matrix organisation and cell survival.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Prolonged induction of p21Cip1/WAF1/CDK2/PCNA complex by epidermal growth factor receptor activation mediates ligand-induced A431 cell growth inhibition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Ligand-induced, p38-dependent apoptosis in cells expressing high levels of epidermal growth factor receptor and ErbB-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Cleavage of epidermal growth factor receptor by caspase during apoptosis is independent of its internalization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M602853200

21 January 2018

Identifiers

10.1074/JBC.M602853200

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 September 2017

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