(Q40258264)

18 September 2017

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title

Biochemical mechanisms in chemical-induced lung injury: roles of metabolic activation (English)

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18 September 2017

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Boyd MR

1

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18 September 2017

language of work or name

English

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publication date

1 August 1980

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Critical Reviews in Toxicology

18 September 2017

published in

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18 September 2017

volume

7

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18 September 2017

issue

2

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18 September 2017

page(s)

103-176

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Carbon tetrachloride hepatotoxicity: an example of lethal cleavage

18 September 2017

cites work

1 reference

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A perspective on the role of chemically reactive metabolites of foreign compounds in toxicity. II. Alterations in the kinetics of covalent binding.

21 January 2018

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Role of metabolic activation in the pathogenesis of chemically induced pulmonary disease: mechanism of action of the lung-toxic furan, 4-ipomeanol

21 January 2018

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Biochemical mechanisms of liver injury

21 January 2018

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Chemical reactivity, biotransformation, and toxicity of polychlorinated aliphatic compounds

21 January 2018

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Primary Pulmonary Responses to Toxic Agents

21 January 2018

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Pulmonary metabolism of xenobiotics

21 January 2018

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https://api.crossref.org/works/10.3109%2F10408448009037487

Effects of 4-ipomeanol, a product from mold-damaged sweet potatoes, on the bovine lung

21 January 2018

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https://api.crossref.org/works/10.3109%2F10408448009037487

Species and strain differences in target organ alkylation and toxicity by 4-ipomeanol. Predictive value of covalent binding in studies of target organ toxicities by reactive metabolites

21 January 2018

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Effects of anti-NADPH-cytochrome c reductase and anti-cytochrome b5 antibodies on the hepatic and pulmonary microsomal metabolism and covalent binding of the pulmonary toxin 4-ipomeanol

21 January 2018

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The many roles of cytochrome 5 in hepatic microsomes

21 January 2018

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https://api.crossref.org/works/10.3109%2F10408448009037487

Cytochrome P-450 and its role in drug metabolism

21 January 2018

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https://api.crossref.org/works/10.3109%2F10408448009037487

Bromobenzene-induced liver necrosis. Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite

21 January 2018

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https://api.crossref.org/works/10.3109%2F10408448009037487

Tolerance mechanisms. Determinants of lung responses to injurious agents

21 January 2018

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https://api.crossref.org/works/10.3109%2F10408448009037487

Renal and hepatic necrosis after metabolic activation of 2-substituted furans and thiophenes, including furosemide and cephaloridine

21 January 2018

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Hepatic microsomal mixed function oxygenase: enzyme multiplicity for the metabolism of carcinogens to DNA-binding metabolites.

21 January 2018

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ORGANIC MATTER IN THE ATMOSPHERE, AND ITS POSSIBLE RELATION TO PETROLEUM FORMATION

21 January 2018

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https://api.crossref.org/works/10.3109%2F10408448009037487

Uptake, distribution, and effects of carbon tetrachloride in rainbow trout (Salmo gairdneri)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

The toxicity of two synthetic 3-substituted furan carbamates.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Perilla ketone: a potent lung toxin from the mint plant, Perilla frutescens Britton

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Carbon tetrachloride activation, lipid peroxidation, and the mixed function oxygenase activity of various rat tissues*1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Potentiation by carbon tetrachloride of NADPH-dependent lipid peroxidation in lung microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Possible mechanism of liver necrosis caused by aromatic organic compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Metabolism and binding of aromatic hydrocarbons in the lung. Relationship to experimental bronchiolar necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Arene oxides: a new aspect of drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Alpha-naphthyl-thiourea-induced pulmonary oedema in the rat: a topographical and electron-microscope study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Studies of the metabolism of carbon disulfide by rat liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Oxidative metabolism of carbon disulphide by the rat. Effect of treatments which modify the liver toxicity of carbon disulphide.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Biochemical changes in rat liver after administration of carbon disulphide, with particular reference to microsomal changes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

S-oxidation of thioureylenes catalyzed by a microsomal flavoprotein mixed-function oxidase.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Fulvine and the pulmonary circulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Monocrotaline induced pulmonary vascular lesions in non-human primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Effect of fulvine on pulmonary arteries and veins of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Effects of phenobarbitone, cinnarizine, and zoxazolamine on the development of right ventricular hypertrophy and hypertensive pulmonary vascular disease in rats treated with monocrotaline

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Pulmonary oedema in rats given dehydromonocrotaline: A topographic and electron-microscope study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Vascular changes in the lungs of rats after the intravenous injection of pyrrole carbamates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Paraquat and related bipyridyls

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Correlation of paraquat toxicity with tissue concentrations and weight loss of the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

The tissue distribution of the bipyridylium herbicides diquat and paraquat in rats and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Paraquat disposition in rats, guinea pigs and monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Fetal toxicity and distribution of paraquat and diquat in mice and rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Tissue uptake of paraquat and diquat

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

In vivo oxidation of reduced nicotinamide-adenine dinucleotide phosphate by paraquat and diquat in rat lung

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Evidence for energy-dependent accumulation of paraquat into rat lung.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Paraquat accumulation: tissue and species specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

The relationship between 5-hydroxytryptamine and paraquat accumulation into rat lung

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

The action of paraquat and diquat on the respiration of liver cell fractions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Superoxide- and singlet oxygen-catalyzed lipid peroxidation as a possible mechanism for paraquat (methyl viologen) toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Bipyridylium quaternary salts and related compounds. V. Pulse radiolysis studies of the reaction of paraquat radical with oxygen. Implications for the mode of action of bipyridyl herbicides

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Interaction of paraquat with the pulmonary microsomal fatty acid desaturase system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

The role of catalytic superoxide formation in the O2 inhibition of nitroreductase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Reduction of paraquat toxicity by superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Paraquat toxicity: proposed mechanism of action involving lipid peroxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

The mode of action of paraquat and diquat

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

The mode of action of the bipyridylium herbicides, paraquat and diquat

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

The role of superoxide and singlet oxygen in lipid peroxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Selenium: Biochemical Role as a Component of Glutathione Peroxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Dissociation of microsomal oxygen reduction and lipid peroxidation with the electron acceptors, paraquat and menadione

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Lipid peroxidation and paraquat toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

On the mechanism of paraquat action on microsomal oxygen reduction and its relation to lipid peroxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

The role of the superoxide anion as a toxic species in the erythrocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Decrease in mouse lung and liver glutathione peroxidase activity and potentiation of the lethal effects of ozone and paraquat by the superoxide dismutase inhibitor diethyldithio-carbamate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Metabolic activation of nitrofurantoin—possible implications for carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Nitroreduction of 5-nitrofuran derivatives by rat liver xanthine oxidase and reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Xanthine oxidase type D (dehydrogenase) in the intestine and other organs of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Superoxide and hydrogen peroxide production and NADPH oxidation stimulated by nitrofurantoin in lung microsomes: Possible implications for toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Early bronchiolar damage following paraquat poisoning in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

The histochemical distribution of aniline hydroxylase in rat tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Ring hydroxylation of di-t-butylhydroxytoluene by rat liver microsomal preparations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Biological fate of butylated hydroxytoluene (BHT); Binding in vitro of BHT to liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Biological fate of butylated hydroxytoluene (BHT); Binding in vivo of BHT to macromolecules of rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Studies on the pathogenesis of butylated hydroxytolueneinduced lung damage in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Proliferation of type II alveolar cells: a review of common responses in toxic lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

The spectrum of drug-induced pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Cytotoxic drug-induced lung disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Generation of free radicals and lipid peroxidation by redox cycling of adriamycin and daunomycin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Toxicity of Mould-damaged Sweet Potatoes (Ipomoea batatas)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

A Lung Oedema Factor from Mouldy Sweet Potatoes (Ipomoea batatas)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Evidence for the Clara cell as a site of cytochrome P450-dependent mixed-function oxidase activity in lung

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Hepatic necrosis caused by furosemide

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Pulmonary bronchiolar alkylation and necrosis by 3-methylfuran, a naturally occurring potential atmospheric contaminant

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

Human pulmonary alveolar macrophages metabolise benzo(a)pyrene to proximate and ultimate mutagens

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448009037487

10.3109/10408448009037487

21 January 2018

Identifiers

DOI

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1 reference