(Q40273686)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16735500%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

Global gene expression analysis of ERK5 and ERK1/2 signaling reveals a role for HIF-1 in ERK5-mediated responses (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16735500%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16735500%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

author name string

Tom Hiu Cheung

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16735500%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Natalie G Ahn

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16735500%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

language of work or name

English

0 references

publication date

30 May 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16735500%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

28 January 2020

number of pages

11

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16735500%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

volume

281

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16735500%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

issue

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16735500%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

page(s)

20993-21003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16735500%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Primary structure of BMK1: a new mammalian map kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Components of a new human protein kinase signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Counting on mitogen-activated protein kinases--ERKs 3, 4, 5, 6, 7 and 8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

c-Src is required for oxidative stress-mediated activation of big mitogen-activated protein kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

MEK kinase 2 and the adaptor protein Lad regulate extracellular signal-regulated kinase 5 activation by epidermal growth factor via Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Structural determinants of aldosterone binding selectivity in the mineralocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Contribution of the ERK5/MEK5 pathway to Ras/Raf signaling and growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Neurotrophins use the Erk5 pathway to mediate a retrograde survival response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Role of MAP kinases in the 1,25-dihydroxyvitamin D3-induced transactivation of the rat cytochrome P450C24 (CYP24) promoter. Specific functions for ERK1/ERK2 and ERK5

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Interaction of myocyte enhancer factor 2 (MEF2) with a mitogen-activated protein kinase, ERK5/BMK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Big mitogen-activated protein kinase (BMK1)/ERK5 protects endothelial cells from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Extracellular signal regulated kinase 5 (ERK5) is required for the differentiation of muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

ERK5 is a novel type of mitogen-activated protein kinase containing a transcriptional activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

14-3-3beta binds to big mitogen-activated protein kinase 1 (BMK1/ERK5) and regulates BMK1 function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Characterization of the MEK5-ERK5 module in human neutrophils and its relationship to ERK1/ERK2 in the chemotactic response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

ERK5 and ERK2 cooperate to regulate NF-kappaB and cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Activation of either ERK1/2 or ERK5 MAP kinase pathways can lead to disruption of the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Essential role for ERK2 mitogen-activated protein kinase in placental development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Erk5 null mice display multiple extraembryonic vascular and embryonic cardiovascular defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Mekk3 is essential for early embryonic cardiovascular development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

The transcription factor MEF2C-null mouse exhibits complex vascular malformations and reduced cardiac expression of angiopoietin 1 and VEGF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Targeted deletion of BMK1/ERK5 in adult mice perturbs vascular integrity and leads to endothelial failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Transactivation and inhibitory domains of hypoxia-inducible factor 1alpha. Modulation of transcriptional activity by oxygen tension

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Significance analysis of microarrays applied to the ionizing radiation response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Rank products: a simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

cAMP inhibits the proliferation of retinal pigmented epithelial cells through the inhibition of ERK1/2 in a PKA-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Epidermal growth factor stimulation of RPE cell survival: contribution of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Microarray analysis of H2O2-, HNE-, or tBH-treated ARPE-19 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Regulation of the MEF2 family of transcription factors by p38

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Transient activation of RAF-1, MEK, and ERK2 coincides kinetically with ternary complex factor phosphorylation and immediate-early gene promoter activity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Oocyte-dependent activation of mitogen-activated protein kinase (ERK1/2) in cumulus cells is required for the maturation of the mouse oocyte-cumulus cell complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Cyclic AMP promotes cAMP-responsive element-binding protein-dependent induction of cellular inhibitor of apoptosis protein-2 and suppresses apoptosis of colon cancer cells through ERK1/2 and p38 MAPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Induction of C-X-C chemokines, growth-related oncogene alpha expression, and epithelial cell-derived neutrophil-activating protein-78 by ML-1 (interleukin-17F) involves activation of Raf1-mitogen-activated protein kinase kinase-extracellular signal-

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Hypoxia induces macrophage inflammatory protein-2 (MIP-2) gene expression in murine macrophages via NF-kappaB: the prominent role of p42/ p44 and PI3 kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Enhanced expression of cyclooxygenase-2 and prostaglandin E2 in response to endotoxin after trauma is dependent on MAPK and NF-kappaB mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Modulation of gene expression by hypoxia in human umbilical cord vein endothelial cells: A transcriptomic and proteomic study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Transcriptional response to hypoxia in human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

MAP kinases and hypoxia in the control of VEGF expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Regulation of glut1 mRNA by hypoxia-inducible factor-1. Interaction between H-ras and hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

MAPK pathway contributes to density- and hypoxia-induced expression of the tumor-associated carbonic anhydrase IX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Further purification and characterization of scrapie prions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Regulation of vascular endothelial growth factor expression by advanced glycation end products

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Effect of hypoxia on gene expression by human hepatocytes (HepG2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Hypoxia induces transcription of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 gene via hypoxia-inducible factor-1alpha activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Hypoxia-inducible factor-1-mediated expression of the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) gene. Its possible role in the Warburg effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Signalling via the hypoxia-inducible factor-1alpha requires multiple posttranslational modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Hydroxylation of HIF-1: oxygen sensing at the molecular level

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

MAPK and Akt act cooperatively but independently on hypoxia inducible factor-1alpha in rasV12 upregulation of VEGF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

ERK5 MAPK regulates embryonic angiogenesis and acts as a hypoxia-sensitive repressor of vascular endothelial growth factor expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

The blood-retinal barriers system. Basic concepts and clinical evaluation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Retinal oxygen: fundamental and clinical aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Identification of functional hypoxia response elements in the promoter region of the DEC1 and DEC2 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Activating transcription factor 4 is translationally regulated by hypoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

6-Phosphofructo-2-kinase (pfkfb3) gene promoter contains hypoxia-inducible factor-1 binding sites necessary for transactivation in response to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

The role of HIF-1 alpha in transcriptional regulation of the proximal tubular epithelial cell response to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Sp1-dependent regulation of the RTP801 promoter and its application to hypoxia-inducible VEGF plasmid for ischemic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Identification of hypoxically inducible mRNAs in HeLa cells using differential-display PCR. Role of hypoxia-inducible factor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Expression of angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 is highly responsive to ambient glutamine availability: role of nuclear factor-kappaB and activating protein-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Hypoxia, but not reoxygenation, induces interleukin 6 gene expression through NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Induction of interleukin (IL)-6 by hypoxia is mediated by nuclear factor (NF)-kappa B and NF-IL6 in cardiac myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Nuclear factor interleukin 6 motifs mediate tissue-specific gene transcription in hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Cooperation between transcription factor AP-1 and NF-kappaB in the induction of interleukin-8 in human pancreatic adenocarcinoma cells by hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Hypoxia upregulates the expression of the NDRG1 gene leading to its overexpression in various human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

The regulation of hypoxic genes by calcium involves c-Jun/AP-1, which cooperates with hypoxia-inducible factor 1 in response to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Coordinate Activation of HIF-1 and NF-κB DNA Binding and COX-2 and VEGF Expression in Retinal Cells by Hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

Hypoxia induces high-mobility-group protein I(Y) and transcription of the cyclooxygenase-2 gene in human vascular endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604208200

21 January 2018

Identifiers

DOI

10.1074/JBC.M604208200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16735500%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference