(Q40293086)

19 September 2017

A molecular dynamics study of Ca(2+)-calmodulin: evidence of interdomain coupling and structural collapse on the nanosecond timescale (English)

1 reference

19 September 2017

Craig M Shepherd

1

1 reference

19 September 2017

Hans J Vogel

series ordinal

2

1 reference

19 September 2017

language of work or name

English

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publication date

1 August 2004

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19 September 2017

12

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inferred from page(s)

published in

Biophysical Journal

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19 September 2017

87

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19 September 2017

2

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19 September 2017

780-791

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Protein-peptide interaction studies demonstrate the versatility of calmodulin target protein binding

19 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Calmodulin's flexibility allows for promiscuity in its interactions with target proteins and peptides

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

A Closed Compact Structure of Native Ca2+-Calmodulin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Structural basis for simultaneous binding of two carboxy-terminal peptides of plant glutamate decarboxylase to calmodulin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Dynamic light scattering study of calmodulin-target peptide complexes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Calmodulin in action: diversity in target recognition and activation mechanisms.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Solution structure of Ca(2+)-calmodulin reveals flexible hand-like properties of its domains

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Calcium-dependent stabilization of the central sequence between Met(76) and Ser(81) in vertebrate calmodulin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Functional dynamics of the hydrophobic cleft in the N-domain of calmodulin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Solvation energetics and conformational change in EF-hand proteins

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Ligand binding and thermodynamic stability of a multidomain protein, calmodulin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

The 1.0 A crystal structure of Ca(2+)-bound calmodulin: an analysis of disorder and implications for functionally relevant plasticity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Diversity of conformational states and changes within the EF-hand protein superfamily

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Structure and dynamics of calmodulin in solution.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Calcium binding decreases the stokes radius of calmodulin and mutants R74A, R90A, and R90G

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

VMD: visual molecular dynamics

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Solution X-ray scattering data show structural differences between yeast and vertebrate calmodulin: implications for structure/function

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Ca(2+)-binding and structural dynamics in the functions of calmodulin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Drug binding by calmodulin: crystal structure of a calmodulin-trifluoperazine complex

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Trifluoperazine-induced conformational change in Ca(2+)-calmodulin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Calcium-induced conformational transition revealed by the solution structure of apo calmodulin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Structure of calmodulin refined at 2.2 A resolution

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

The central helix of calmodulin functions as a flexible tether.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Helix stabilization by Glu-...Lys+ salt bridges in short peptides of de novo design

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Structural dynamics of calmodulin and troponin C.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Measurement of the exchange rates of rapidly exchanging amide protons: Application to the study of calmodulin and its complex with a myosin light chain kinase fragment

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Solution structure of a calmodulin-target peptide complex by multidimensional NMR

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Target enzyme recognition by calmodulin: 2.4 A structure of a calmodulin-peptide complex

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Calmodulin structure refined at 1.7 A resolution

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Surface exposure of the methionine side chains of calmodulin in solution. A nitroxide spin label and two-dimensional NMR study.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Interactions between domains of apo calmodulin alter calcium binding and stability.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Bending of the calmodulin central helix: a theoretical study

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Calcium-induced interactions of calmodulin domains revealed by quantitative thrombin footprinting of Arg37 and Arg106.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Comparison of the crystal and solution structures of calmodulin and troponin C

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Backbone dynamics of calmodulin studied by 15N relaxation using inverse detected two-dimensional NMR spectroscopy: the central helix is flexible.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Molecular dynamics simulations of pentapeptides at interfaces: salt bridge and cation-pi interactions

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Protein conformational changes studied by diffusion NMR spectroscopy: application to helix-loop-helix calcium binding proteins

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Mutation of Tyr138 disrupts the structural coupling between the opposing domains in vertebrate calmodulin

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Construction and molecular dynamics simulation of calmodulin in the extended and in a bent conformation

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1304488

Calcium-dependent and -independent interactions of the calmodulin-binding domain of cyclic nucleotide phosphodiesterase with calmodulin

20 August 2018

1 reference

12 December 2020

Quantitative endoproteinase GluC footprinting of cooperative Ca2+ binding to calmodulin: proteolytic susceptibility of E31 and E87 indicates interdomain interactions

1 reference

12 December 2020

Helix Propensities of Basic Amino Acids Increase with the Length of the Side-chain

1 reference

12 December 2020

Calcium-dependent structural coupling between opposing globular domains of calmodulin involves the central helix

1 reference

12 December 2020

The whole is not the simple sum of its parts in calmodulin from S. cerevisiae

1 reference

12 December 2020

Proteolytic footprinting titrations for estimating ligand-binding constants and detecting pathways of conformational switching of calmodulin

1 reference

12 December 2020

Closer proximity between opposing domains of vertebrate calmodulin following deletion of Met(145)-Lys(148)

1 reference

12 December 2020

Structure and dynamics of calcium-activated calmodulin in solution.

1 reference

12 December 2020

An interdomain linker increases the thermostability and decreases the calcium affinity of the calmodulin N-domain

1 reference

12 December 2020

Small-angle solution scattering reveals information on conformational dynamics in calcium-binding proteins and in their interactions with regulatory targets

1 reference

12 December 2020

Vector geometry mapping. A method to characterize the conformation of helix-loop-helix calcium-binding proteins

1 reference

12 December 2020

Molecular dynamics simulations of calcium-free calmodulin in solution

1 reference

12 December 2020

Molecular dynamics simulations revealed Ca(2+)-dependent conformational change of Calmodulin

1 reference

12 December 2020

Calcium-induced conformational switching of Paramecium calmodulin provides evidence for domain coupling

1 reference

12 December 2020

Basic interdomain boundary residues in calmodulin decrease calcium affinity of sites I and II by stabilizing helix-helix interactions

1 reference

12 December 2020

Binding of both Ca2+ and mastoparan to calmodulin induces a large change in the tertiary structure

1 reference

12 December 2020

Inter-domain interaction and the structural flexibility of calmodulin in the connecting region of the terminal two domains

1 reference

12 December 2020

Thermodynamics of Ca2+ binding to calmodulin and its tryptic fragments

1 reference

12 December 2020

Evidence for calmodulin inter-domain compaction in solution induced by W-7 binding

1 reference

12 December 2020

10.1529/BIOPHYSJ.103.033266

Identifiers

DOI

1 reference

19 September 2017

1 reference

19 September 2017

PubMed publication ID

15298887

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