(Q40295334)

English

Gene expression analysis of troglitazone reveals its impact on multiple pathways in cell culture: a case for in vitro platforms combined with gene expression analysis for early (idiosyncratic) toxicity screening

scientific article published on March 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Gene expression analysis of troglitazone reveals its impact on multiple pathways in cell culture: a case for in vitro platforms combined with gene expression analysis for early (idiosyncratic) toxicity screening (English)

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

author name string

Gordon Vansant

1

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Patrick Pezzoli

2

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Robert Saiz

3

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Aaron Birch

4

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Chris Duffy

5

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Francois Ferre

6

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Joseph Monforte

7

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

publication date

1 March 2006

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

International Journal of Toxicology

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

25

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

85-94

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Troglitazone but not rosiglitazone induces G1 cell cycle arrest and apoptosis in human and rat hepatoma cell lines

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

Haem, haem oxygenase and ferritin in vascular endothelial cell injury

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

Repression of cytochrome P450 1A1 gene expression by oxidative stress: mechanisms and biological implications

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

Contribution of hepatic cytochrome P450 systems to the generation of reactive oxygen species

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

Growth and DNA damage-inducible transcription factor 153 mediates apoptosis in response to fenretinide but not synergy between fenretinide and chemotherapeutic drugs in neuroblastoma.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

Unique ability of troglitazone to up-regulate peroxisome proliferator-activated receptor-gamma expression in hepatocytes

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

The steroid and thyroid hormone receptor superfamily

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

Subacute hepatic failure associated with a new antidiabetic agent, troglitazone: a case report with autopsy examination

1 reference

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21 January 2018

Adverse hepatic drug reactions: inflammatory episodes as consequence and contributor

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

Troglitazone quinone formation catalyzed by human and rat CYP3A: an atypical CYP oxidation reaction

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

Hexobarbital-binding, hydroxylation and hexobarbital-dependent hydrogen peroxide production in hepatic microsomes of guinea pig, rat and rabbit.

1 reference

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21 January 2018

Phenol sulfotransferase, ST1A3, as the main enzyme catalyzing sulfation of troglitazone in human liver

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

Raised levels of exhaled carbon monoxide are associated with an increased expression of heme oxygenase-1 in airway macrophages in asthma: a new marker of oxidative stress

1 reference

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21 January 2018

Role of phenobarbital-inducible cytochrome P450s as a source of active oxygen species in DNA-oxidation

1 reference

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21 January 2018

Heme-oxygenase-1 response, a marker of oxidative stress, in a mouse model of AA amyloidosis

1 reference

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21 January 2018

Troglitazone enhances the hepatotoxicity of acetaminophen by inducing CYP3A in rats

1 reference

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21 January 2018

A review of the common properties of drugs with idiosyncratic hepatotoxicity and the "multiple determinant hypothesis" for the manifestation of idiosyncratic drug toxicity.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

Lack of effect of type II diabetes on the pharmacokinetics of troglitazone in a multiple-dose study.

1 reference

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21 January 2018

15-deoxy prostaglandin J2 enhances allyl alcohol-induced toxicity in rat hepatocytes

1 reference

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21 January 2018

Troglitazone-induced hepatic failure leading to liver transplantation. A case report

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

Induction of cytochrome P450 enzymes and over-generation of oxygen radicals in beta-carotene supplemented rats.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

Identification of glutathione conjugates of troglitazone in human hepatocytes

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

Production of reactive oxygen species by microsomes enriched in specific human cytochrome P450 enzymes

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

The heme synthesis and degradation pathways: role in oxidant sensitivity. Heme oxygenase has both pro- and antioxidant properties

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

Effect of troglitazone on cytochrome P450 enzymes in primary cultures of human and rat hepatocytes

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

Thiazolidinediones in the treatment of insulin resistance and type II diabetes

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

Activation of peroxisome proliferator-activated receptor-gamma stimulates the growth arrest and DNA-damage inducible 153 gene in non-small cell lung carcinoma cells

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

The danger hypothesis applied to idiosyncratic drug reactions

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

PPAR-gamma: adipogenic regulator and thiazolidinedione receptor

1 reference

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21 January 2018

Induction of GADD45 and GADD153 in neuroblastoma cells by dopamine-induced toxicity.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

Transient enhancement of heme oxygenase 1 mRNA accumulation: a marker of oxidative stress to eukaryotic cells.

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

The PPARs: from orphan receptors to drug discovery

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

Formation of a novel quinone epoxide metabolite of troglitazone with cytotoxicity to HepG2 cells

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

Signaling pathways involved in induction of GADD45 gene expression and apoptosis by troglitazone in human MCF-7 breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1080%2F10915810600605690

21 January 2018

Role of Drug Disposition in Drug Hypersensitivity: A Chemical, Molecular, and Clinical Perspective

1 reference

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21 January 2018

Identifiers

10.1080/10915810600605690

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

ResearchGate publication ID

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