(Q40311479)

19 September 2017

title

17-AAG, an Hsp90 inhibitor, causes kinetochore defects: a novel mechanism by which 17-AAG inhibits cell proliferation (English)

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19 September 2017

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Niikura Y

1

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19 September 2017

Ohta S

2

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19 September 2017

Vandenbeldt KJ

3

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19 September 2017

Abdulle R

4

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19 September 2017

McEwen BF

5

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19 September 2017

Kitagawa K

6

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19 September 2017

language of work or name

English

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publication date

27 February 2006

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19 September 2017

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19 September 2017

volume

25

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19 September 2017

issue

30

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19 September 2017

page(s)

4133-4146

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209461

19 September 2017

exact match

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cites work

Hsp90 inhibition depletes Chk1 and sensitizes tumor cells to replication stress

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Sgt1 associates with Hsp90: an initial step of assembly of the core kinetochore complex

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Ansamycin antibiotics inhibit Akt activation and cyclin D expression in breast cancer cells that overexpress HER2.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Hsp90: an emerging target for breast cancer therapy

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7 January 2021

Captivating capture: how microtubules attach to kinetochores.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Survivin is required for stable checkpoint activation in taxol-treated HeLa cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Budding yeast SKP1 encodes an evolutionarily conserved kinetochore protein required for cell cycle progression

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Heat shock protein 90 regulates the metaphase-anaphase transition in a polo-like kinase-dependent manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Hec1 and nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Identification of essential components of the S. cerevisiae kinetochore

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Regulation of survivin function by Hsp90

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7 January 2021

Phase I trial of 17-allylamino-17-demethoxygeldanamycin in patients with advanced cancer

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7 January 2021

The Hsp90 chaperone complex as a novel target for cancer therapy

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

NDC10: a gene involved in chromosome segregation in Saccharomyces cerevisiae

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

The importance of ATP binding and hydrolysis by hsp90 in formation and function of protein heterocomplexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Isolation and characterization of a gene (CBF2) specifying a protein component of the budding yeast kinetochore

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Regulating the yeast kinetochore by ubiquitin-dependent degradation and Skp1p-mediated phosphorylation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

DT-Diaphorase expression and tumor cell sensitivity to 17-allylamino, 17-demethoxygeldanamycin, an inhibitor of heat shock protein 90

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

In vivo site-directed mutagenesis of yeast plasmids using a three-fragment homologous recombination system

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Evolutionary conservation between budding yeast and human kinetochores

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Transcriptional coactivator Cited2 induces Bmi1 and Mel18 and controls fibroblast proliferation via Ink4a/ARF

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Tetratrico peptide repeat interactions: to TPR or not to TPR?

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

A 240 kd multisubunit protein complex, CBF3, is a major component of the budding yeast centromere

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

A zinc finger protein, essential for chromosome segregation, constitutes a putative DNA binding subunit of the Saccharomyces cerevisiae kinetochore complex, Cbf3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

The interaction between Sgt1p and Skp1p is regulated by HSP90 chaperones and is required for proper CBF3 assembly

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

A human centromere antigen (CENP-B) interacts with a short specific sequence in alphoid DNA, a human centromeric satellite

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

CENP-E is essential for reliable bioriented spindle attachment, but chromosome alignment can be achieved via redundant mechanisms in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Kinetochore fiber maturation in PtK1 cells and its implications for the mechanisms of chromosome congression and anaphase onset

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

A dual role for Bub1 in the spindle checkpoint and chromosome congression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Heat shock protein 90.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Yeast is selectively hypersensitised to heat shock protein 90 (Hsp90)-targetting drugs with heterologous expression of the human Hsp90beta, a property that can be exploited in screens for new Hsp90 chaperone inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Inactivation of the retinoblastoma protein family can bypass the HCF-1 defect in tsBN67 cell proliferation and cytokinesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Sgt1 is required for human kinetochore assembly

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Hsp90 enables Ctf13p/Skp1p to nucleate the budding yeast kinetochore

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

CEP3 encodes a centromere protein of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

The ORC1 cycle in human cells: I. cell cycle-regulated oscillation of human ORC1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Replication timing of DNA sequences associated with human centromeres and telomeres

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Overview: Translating Hsp90 Biology into Hsp90 Drugs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Silencing mitosin induces misaligned chromosomes, premature chromosome decondensation before anaphase onset, and mitotic cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Centromere protein B of African green monkey cells: gene structure, cellular expression, and centromeric localization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209461

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209461

1 reference

Dimensions Publication ID

19 September 2017

1049973965

0 references

1 reference