(Q40314573)

English

Blockade of TNF-alpha decreases both inflammation and efficacy of intrapulmonary Ad.IFNbeta immunotherapy in an orthotopic model of bronchogenic lung cancer

scientific article published on 17 February 2006

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scholarly article

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Europe PubMed Central

PubMed publication ID

19 September 2017

Blockade of TNF-alpha decreases both inflammation and efficacy of intrapulmonary Ad.IFNbeta immunotherapy in an orthotopic model of bronchogenic lung cancer (English)

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

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author name string

Michael J Wilderman

1

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Samuel Kim

2

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Collin T Gillespie

3

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Europe PubMed Central

PubMed publication ID

19 September 2017

Jing Sun

4

1 reference

Europe PubMed Central

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19 September 2017

Veena Kapoor

5

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Anil Vachani

6

1 reference

Europe PubMed Central

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19 September 2017

Daniel H Sterman

7

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Larry R Kaiser

8

1 reference

Europe PubMed Central

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19 September 2017

Steven M Albelda

9

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Europe PubMed Central

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19 September 2017

publication date

17 February 2006

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19 September 2017

Molecular Therapy

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Europe PubMed Central

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19 September 2017

13

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19 September 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

910-917

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Tumour immunotherapy using an adenoviral vector expressing a membrane-bound mutant of murine TNF alpha

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Immunotherapy of established tumors in mice by intratumoral injection of an adenovirus vector harboring the human IL-2 cDNA: induction of CD8(+) T-cell immunity and NK activity

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Adenovirus-mediated interferon-beta gene therapy suppresses growth and metastasis of human prostate cancer in nude mice

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Intrapulmonary IFN-beta gene therapy using an adenoviral vector is highly effective in a murine orthotopic model of bronchogenic adenocarcinoma of the lung.

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Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

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Rising incidence of bronchioloalveolar lung carcinoma and its unique clinicopathologic features

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Bronchioloalveolar carcinoma: a model for investigating the biology of epidermal growth factor receptor inhibition

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The innate immune response to adenovirus vectors

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Nonspecific inflammation inhibits adenovirus-mediated pulmonary gene transfer and expression independent of specific acquired immune responses.

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Internalization of adenovirus by alveolar macrophages initiates early proinflammatory signaling during acute respiratory tract infection

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Delayed-type hypersensitivity response to high doses of adenoviral vectors

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Upregulation of class I major histocompatibility complex antigens by interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo

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Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: toxicity study

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Characterization of human proliferative T cell responses to adenovirus

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Phase I trial of recombinant adenovirus gene transfer in lung cancer. Longitudinal study of the immune responses to transgene and viral products

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7 January 2021

Tumor necrosis factor alpha plays a central role in immune-mediated clearance of adenoviral vectors

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7 January 2021

TNF-alpha receptor signaling and IL-10 gene therapy regulate the innate and humoral immune responses to recombinant adenovirus in the lung

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7 January 2021

Inhibition of tumor necrosis factor alpha decreases inflammation and prolongs adenovirus gene expression in lung and liver

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7 January 2021

TNF-alpha -dependent maturation of local dendritic cells is critical for activating the adaptive immune response to virus infection

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7 January 2021

Adenovirus-induced maturation of dendritic cells through a PI3 kinase-mediated TNF-alpha induction pathway

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7 January 2021

Interferon-gamma (IFN-gamma)- and tumour necrosis factor (TNF)-induced nitric oxide as toxic effector molecule in chronic dextran sulphate sodium (DSS)-induced colitis in mice

1 reference

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7 January 2021

Incorporation of adenovirus in calcium phosphate precipitates enhances gene transfer to airway epithelia in vitro and in vivo

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7 January 2021

Inhibition of tumor necrosis factor alpha by an adenovirus-encoded soluble fusion protein extends transgene expression in the liver and lung

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10.1016/J.YMTHE.2005.12.012

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

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