(Q40317934)

19 September 2017

title

Activation of the apoptotic JNK pathway through the Rac1-binding scaffold protein POSH. (English)

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19 September 2017

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Zhiheng Xu

1

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19 September 2017

Lloyd A Greene

series ordinal

2

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19 September 2017

language of work or name

English

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publication date

1 January 2006

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19 September 2017

published in

Methods in Enzymology

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19 September 2017

volume

406

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19 September 2017

page(s)

479-489

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c-Jun-NH2 kinase (JNK) contributes to the regulation of c-Myc protein stability.

19 September 2017

cites work

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JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

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Cep-1347 (KT7515), a semisynthetic inhibitor of the mixed lineage kinase family.

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Recruitment of JNK to JIP1 and JNK-dependent JIP1 phosphorylation regulates JNK module dynamics and activation

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https://api.crossref.org/works/10.1016%2FS0076-6879%2806%2906036-8

7 January 2021

A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways

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7 January 2021

MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines

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The JNK signal transduction pathway

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7 January 2021

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

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7 January 2021

POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis.

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7 January 2021

Regulation of apoptotic c-Jun N-terminal kinase signaling by a stabilization-based feed-forward loop.

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7 January 2021

The MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosis

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10.1016/S0076-6879(06)06036-8

Identifiers

DOI

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19 September 2017

1 reference