(Q40320402)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16459330%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

Oncostatin M receptor-mediated signal transduction is negatively regulated by SOCS3 through a receptor tyrosine-independent mechanism (English)

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16 January 2020

6

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16 January 2020

author name string

Claudia Stross

1

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16 January 2020

Simone Radtke

2

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16 January 2020

Thomas Clahsen

3

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16 January 2020

Christa Gerlach

4

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16 January 2020

Rudolf Volkmer-Engert

5

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16 January 2020

Peter C Heinrich

7

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16 January 2020

Heike M Hermanns

8

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16 January 2020

language of work or name

English

0 references

publication date

2 February 2006

1 reference

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Journal of Biological Chemistry

16 January 2020

published in

1 reference

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16 January 2020

volume

281

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16 January 2020

issue

13

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16 January 2020

page(s)

8458-8468

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Interleukin-6 and the acute phase response

16 January 2020

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Inhibition of IL-6 for the treatment of inflammatory diseases

21 January 2018

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Spontaneous release of leukemia inhibitory factor and oncostatin-M is increased in supernatants of short-term organ cultures from lesional psoriatic skin

21 January 2018

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Molecular cloning and expression of an IL-6 signal transducer, gp130

21 January 2018

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Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

21 January 2018

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WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27

21 January 2018

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Murine oncostatin M stimulates mouse synovial fibroblasts in vitro and induces inflammation and destruction in mouse joints in vivo.

21 January 2018

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A model of inflammatory arthritis highlights a role for oncostatin M in pro-inflammatory cytokine-induced bone destruction via RANK/RANKL

21 January 2018

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Secretion of oncostatin M by neutrophils in rheumatoid arthritis

21 January 2018

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Targeted disruption of oncostatin M receptor results in altered hematopoiesis

21 January 2018

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Hepatocyte proliferation and tissue remodeling is impaired after liver injury in oncostatin M receptor knockout mice

21 January 2018

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SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130

21 January 2018

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The tyrosine 974 within the LIF-R-chain of the gp130/LIF-R heteromeric receptor complex mediates negative regulation of LIF signalling.

21 January 2018

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SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130

21 January 2018

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Principles of interleukin (IL)-6-type cytokine signalling and its regulation

21 January 2018

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Regulation of Jak2 through the ubiquitin-proteasome pathway involves phosphorylation of Jak2 on Y1007 and interaction with SOCS-1.

21 January 2018

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The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

21 January 2018

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Cytokine-inducible SH2 protein-3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N-terminal kinase inhibitory region as well as SH2 domain

21 January 2018

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Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

21 January 2018

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Desensitization of Signaling by Oncostatin M in Human Vascular Cells Involves Cytoplasmic Tyr Residue 759 in gp130 but Is Not Mediated by Either Src Homology 2 Domain-containing Tyrosine Phosphatase 2 or Suppressor of Cytokine Signaling 3

21 January 2018

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Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice

21 January 2018

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A novel type I cytokine receptor is expressed on monocytes, signals proliferation, and activates STAT-3 and STAT-5

21 January 2018

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GPL, a Novel Cytokine Receptor Related to GP130 and Leukemia Inhibitory Factor Receptor

21 January 2018

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The role of the inhibitors of interleukin-6 signal transduction SHP2 and SOCS3 for desensitization of interleukin-6 signalling

21 January 2018

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IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages

21 January 2018

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Non-redundant signal transduction of interleukin-6-type cytokines. The adapter protein Shc is specifically recruited to rhe oncostatin M receptor

21 January 2018

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Signal transduction of IL-6, leukemia-inhibitory factor, and oncostatin M: structural receptor requirements for signal attenuation

21 January 2018

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A family of cytokine-inducible inhibitors of signalling

21 January 2018

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A new protein containing an SH2 domain that inhibits JAK kinases

21 January 2018

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Structure and function of a new STAT-induced STAT inhibitor

21 January 2018

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Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation

21 January 2018

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The family of the IL-6-type cytokines: specificity and promiscuity of the receptor complexes

21 January 2018

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Autoregulation of pituitary corticotroph SOCS-3 expression: characterization of the murine SOCS-3 promoter

21 January 2018

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Analysis of SOCS-3 promoter responses to interferon gamma

21 January 2018

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The MKK6/p38 mitogen-activated protein kinase pathway is capable of inducing SOCS3 gene expression and inhibits IL-6-induced transcription

21 January 2018

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Suppressors of cytokine signaling (SOCS)-1 and SOCS-3 are induced by CpG-DNA and modulate cytokine responses in APCs

21 January 2018

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The inhibition of interleukin-6-dependent STAT activation by mitogen-activated protein kinases depends on tyrosine 759 in the cytoplasmic tail of glycoprotein 130.

21 January 2018

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Oncostatin M-induced activation of stress-activated MAP kinases depends on tyrosine 861 in the OSM receptor and requires Jak1 but not Src kinases

21 January 2018

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SOCS3 negatively regulates IL-6 signaling in vivo

21 January 2018

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SH2 domains from suppressor of cytokine signaling-3 and protein tyrosine phosphatase SHP-2 have similar binding specificities

21 January 2018

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A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor

21 January 2018

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Suppressor of cytokine signaling-3 is recruited to the activated granulocyte-colony stimulating factor receptor and modulates its signal transduction

21 January 2018

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Identification of the Y985 and Y1077 motifs as SOCS3 recruitment sites in the murine leptin receptor

21 January 2018

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SOCS-3 is an insulin-induced negative regulator of insulin signaling

21 January 2018

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Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3

21 January 2018

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Oncostatin M regulates the synthesis and turnover of gp130, leukemia inhibitory factor receptor alpha, and oncostatin M receptor beta by distinct mechanisms.

21 January 2018

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Interleukin-6-induced proliferation of pre-B cells mediated by receptor complexes lacking the SHP2/SOCS3 recruitment sites revisited.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M511212200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16459330%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference