(Q40321040)

19 September 2017

title

Endostatin therapy reveals a U-shaped curve for antitumor activity (English)

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19 September 2017

Tjin Tham Sjin RM

1

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19 September 2017

Naspinski J

2

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19 September 2017

Birsner AE

3

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19 September 2017

Li C

4

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19 September 2017

Chan R

5

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19 September 2017

Lo KM

6

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19 September 2017

Gillies S

7

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19 September 2017

Zurakowski D

8

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19 September 2017

Folkman J

9

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19 September 2017

Samulski J

10

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19 September 2017

Javaherian K

11

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19 September 2017

publication date

1 June 2006

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19 September 2017

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19 September 2017

volume

13

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19 September 2017

issue

6

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19 September 2017

page(s)

619-627

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https://scigraph.springernature.com/pub.10.1038/sj.cgt.7700938

19 September 2017

exact match

0 references

cites work

Angiogenesis in cancer, vascular, rheumatoid and other disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a lewis lung carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Endostatin: an endogenous inhibitor of angiogenesis and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Antiangiogenic therapy of transgenic mice impairs de novo tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by alpha v beta 3 and alpha 5 beta 1 integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Cell surface glypicans are low-affinity endostatin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Antiangiogenesis signals by endostatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Endostatin blocks vascular endothelial growth factor-mediated signaling via direct interaction with KDR/Flk-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Endostatin is a potential inhibitor of Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Endostatin Inhibits Human Tongue Carcinoma Cell Invasion and Intravasation and Blocks the Activation of Matrix Metalloprotease-2, -9, and -13

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Endostatin binds to the catalytic domain of matrix metalloproteinase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Endostatin's antiangiogenic signaling network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

A 27-amino-acid synthetic peptide corresponding to the NH2-terminal zinc-binding domain of endostatin is responsible for its antitumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Adenovirus-mediated gene transfer of endostatin in vivo results in high level of transgene expression and inhibition of tumor growth and metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Antiangiogenic gene therapy for cancer via systemic administration of adenoviral vectors expressing secretable endostatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Evaluation of endostatin antiangiogenesis gene therapy in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Inhibition of the mammary carcinoma angiogenic switch in C3(1)/SV40 transgenic mice by a mutated form of human endostatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Adenovirus-mediated human endostatin gene delivery demonstrates strain-specific antitumor activity and acute dose-dependent toxicity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Treatment of colorectal and hepatocellular carcinomas by adenoviral mediated gene transfer of endostatin and angiostatin-like molecule in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Adeno-associated virus-mediated gene transfer of endostatin inhibits angiogenesis and tumor growth in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Gene therapy delivery of endostatin enhances the treatment efficacy of radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Adeno-associated virus 2-mediated antiangiogenic cancer gene therapy: long-term efficacy of a vector encoding angiostatin and endostatin over vectors encoding a single factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Adeno-associated viral vector-mediated expression of endostatin inhibits tumor growth and metastasis in an orthotropic pancreatic cancer model in hamsters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Effects of angiogenesis inhibitors on multistage carcinogenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Gene transfer by adeno-associated virus vectors into the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Laminin modulates morphogenic properties of the collagen XVIII endostatin domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Zinc-dependent dimers observed in crystals of human endostatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Several log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Anti-tumor efficacy of human angiostatin using liver-mediated adeno-associated virus gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

PPARgamma ligands inhibit primary tumor growth and metastasis by inhibiting angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Continuous intravascular secretion of endostatin in mice from transduced hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Antibodies to endostatin in a multifocal glioblastoma patient.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

Endostatin Associates with Lipid Rafts and Induces Reorganization of the Actin Cytoskeleton via Down-regulation of RhoA Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

The antitumoral effect of endostatin and angiostatin is associated with a down-regulation of vascular endothelial growth factor expression in tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

7 January 2021

Adeno-associated virus mediated endostatin gene therapy in combination with topoisomerase inhibitor effectively controls liver tumor in mouse model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

7 January 2021

High level expression and secretion of Fc-X fusion proteins in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

7 January 2021

A "humanized" green fluorescent protein cDNA adapted for high-level expression in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

7 January 2021

Therapeutic efficacy of endostatin exhibits a biphasic dose-response curve

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700938

7 January 2021

Identifiers

DOI

10.1038/SJ.CGT.7700938

1 reference

Dimensions Publication ID

19 September 2017

1019691444

0 references

1 reference