(Q40325258)

19 September 2017

title

NUR77 exerts a protective effect against inflammatory bowel disease by negatively regulating the TRAF6/TLR-IL-1R signalling axis (English)

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inflammatory bowel diseases

19 September 2017

main subject

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toll-like receptor

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author name string

Hua Wu

1

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19 September 2017

Xiu-Ming Li

2

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19 September 2017

Jing-Ru Wang

3

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19 September 2017

Wen-Juan Gan

4

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19 September 2017

Fu-Quan Jiang

5

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19 September 2017

Yao Liu

6

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19 September 2017

Xin-Dao Zhang

7

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19 September 2017

Xiao-Shun He

8

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19 September 2017

Yuan-Yuan Zhao

9

1 reference

19 September 2017

Xing-Xing Lu

10

1 reference

19 September 2017

Yan-Bing Guo

11

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19 September 2017

Xiao-Kun Zhang

12

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19 September 2017

Jian-Ming Li

13

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19 September 2017

language of work or name

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13 November 2015

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19 September 2017

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19 September 2017

volume

238

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19 September 2017

issue

3

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19 September 2017

page(s)

457-469

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Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

19 September 2017

cites work

1 reference

Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review

21 January 2018

1 reference

Inflammatory Bowel Disease

21 January 2018

1 reference

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

1 reference

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

1 reference

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

21 January 2018

1 reference

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

21 January 2018

1 reference

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

21 January 2018

1 reference

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

21 January 2018

1 reference

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

21 January 2018

1 reference

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

21 January 2018

1 reference

Surgical management of ulcerative colitis in the era of biologicals

21 January 2018

1 reference

Identification of the DNA binding site for NGFI-B by genetic selection in yeast

21 January 2018

1 reference

Novel dimeric Nur77 signaling mechanism in endocrine and lymphoid cells

21 January 2018

1 reference

Unique response pathways are established by allosteric interactions among nuclear hormone receptors

21 January 2018

1 reference

Targeting Nur77 translocation

21 January 2018

1 reference

Regulation of Nur77 expression by β-catenin and its mitogenic effect in colon cancer cells.

21 January 2018

1 reference

Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3.

21 January 2018

1 reference

Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3

21 January 2018

1 reference

A short Nur77-derived peptide converts Bcl-2 from a protector to a killer

21 January 2018

1 reference

Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway

21 January 2018

1 reference

Increased macrophage subset in inflammatory bowel disease: apparent recruitment from peripheral blood monocytes

21 January 2018

1 reference

Changes of the cytokine profile in inflammatory bowel diseases

21 January 2018

1 reference

Cytosporone B is an agonist for nuclear orphan receptor Nur77.

21 January 2018

1 reference

A Failure of Transforming Growth Factor-β1 Negative Regulation Maintains Sustained NF-κB Activation in Gut Inflammation

21 January 2018

1 reference

Nuclear factor kappaB is activated in macrophages and epithelial cells of inflamed intestinal mucosa

21 January 2018

1 reference

Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation

21 January 2018

1 reference

Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis

21 January 2018

1 reference

Commentary: the role of the IL-18 system and other members of the IL-1R/TLR superfamily in innate mucosal immunity and the pathogenesis of inflammatory bowel disease: friend or foe?

21 January 2018

1 reference

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

21 January 2018

1 reference

Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling

21 January 2018

1 reference

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

21 January 2018

1 reference

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

21 January 2018

1 reference

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination

21 January 2018

1 reference

Nur77 decreases atherosclerosis progression in apoE(-/-) mice fed a high-fat/high-cholesterol diet

21 January 2018

1 reference

Reduction of the incidence and severity of collagen-induced arthritis by constitutive Nur77 expression in the T cell lineage.

21 January 2018

1 reference

Targeting NR4A1 (TR3) in cancer cells and tumors

21 January 2018

1 reference

Orphan nuclear receptor Nur77 promotes colorectal cancer invasion and metastasis by regulating MMP-9 and E-cadherin.

21 January 2018

1 reference

The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C- monocytes

21 January 2018

1 reference

NR4A1 (Nur77) deletion polarizes macrophages toward an inflammatory phenotype and increases atherosclerosis

21 January 2018

1 reference

Nuclear receptors Nur77, Nurr1, and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses

21 January 2018

1 reference

Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation

21 January 2018

1 reference

Nur77 deficiency leads to systemic inflammation in elderly mice

21 January 2018

1 reference

Modulation of orphan nuclear receptor Nur77-mediated apoptotic pathway by acetylshikonin and analogues

21 January 2018

1 reference

TRAF6 is a signal transducer for interleukin-1

21 January 2018

1 reference

Toll-like receptor signalling

21 January 2018

1 reference

Targeting TLR/IL-1R signalling in human diseases.

21 January 2018

1 reference

Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88

21 January 2018

1 reference

TLR-4 signaling promotes tumor growth and paclitaxel chemoresistance in ovarian cancer

21 January 2018

1 reference

Regulation of Nur77 nuclear export by c-Jun N-terminal kinase and Akt.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/PATH.4670

1 reference

19 September 2017

1 reference