(Q40325392)

English

The R273H p53 mutation can facilitate the androgen-independent growth of LNCaP by a mechanism that involves H2 relaxin and its cognate receptor LGR7.

scientific article published on March 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

The R273H p53 mutation can facilitate the androgen-independent growth of LNCaP by a mechanism that involves H2 relaxin and its cognate receptor LGR7. (English)

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

author name string

Vinall RL

1

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Tepper CG

2

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Shi XB

3

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Xue LA

4

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Gandour-Edwards R

5

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

de Vere White RW

6

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

language of work or name

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publication date

1 March 2006

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Europe PubMed Central

PubMed publication ID

19 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

25

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

14

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

2082-2093

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

Neuroendocrine cells in prostate cancer

1 reference

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Relaxin signalling links tyrosine phosphorylation to phosphodiesterase and adenylyl cyclase activity

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Relaxin: new peptides, receptors and novel actions

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The effects of wild-type p53 tumor suppressor activity and mutant p53 gain-of-function on cell growth

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Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study

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Modulation of activity of the promoter of the human MDR1 gene by Ras and p53.

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Mechanisms of endocrine therapy-responsive and -unresponsive prostate tumours

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Frequency and characterization of p53 mutations in primary and metastatic human prostate cancer.

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Demonstration of upregulated H2 relaxin mRNA expression during neuroendocrine differentiation of LNCaP prostate cancer cells and production of biologically active mammalian recombinant 6 histidine-tagged H2 relaxin

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Isolation and analysis of the 3'-untranslated regions of the human relaxin H1 and H2 genes

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The Hallmarks of Cancer

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The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7

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21 January 2018

Activation of orphan receptors by the hormone relaxin

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Studies on Prostatic Cancer: I. The Effect of Castration, Of Estrogen and of Androgen Injection on Serum Phosphatases in Metastatic Carcinoma of the Prostate

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Relaxin peptides are new global players.

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21 January 2018

Expression of the human relaxin gene in the corpus luteum of the menstrual cycle and in the prostate

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21 January 2018

Update on hormone-refractory prostate cancer

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p42/p44 Mitogen-activated protein kinase signal transduction pathway: a novel target for the treatment of hormone-resistant prostate cancer?

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'Gain of function' phenotype of tumor-derived mutant p53 requires the oligomerization/nonsequence-specific nucleic acid-binding domain

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21 January 2018

Interleukin-8 confers androgen-independent growth and migration of LNCaP: differential effects of tyrosine kinases Src and FAK.

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21 January 2018

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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21 January 2018

The IARC TP53 database: new online mutation analysis and recommendations to users

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21 January 2018

Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer

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21 January 2018

Mutant p53: gain-of-function oncoproteins and wild-type p53 inactivators

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21 January 2018

Relaxin is a key mediator of prostate growth and male reproductive tract development

1 reference

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21 January 2018

Tumor-derived p53 mutants induce oncogenesis by transactivating growth-promoting genes.

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21 January 2018

Relaxin's physiological roles and other diverse actions

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21 January 2018

A modified yeast assay used on archival samples of localized prostate cancer tissue improves the detection of p53 abnormalities and increases their predictive value

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21 January 2018

Molecular alterations associated with LNCaP cell progression to androgen independence

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21 January 2018

Complex functions of mutant p53 alleles from human prostate cancer

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21 January 2018

H2 relaxin overexpression increases in vivo prostate xenograft tumor growth and angiogenesis

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21 January 2018

Relaxin‐like peptides in cancer

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21 January 2018

Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer

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21 January 2018

Profiling of gene expression changes caused by p53 gain-of-function mutant alleles in prostate cancer cells

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21 January 2018

Surfing the p53 network

1 reference

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21 January 2018

Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum

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Relaxin activates the MAP kinase pathway in human endometrial stromal cells

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21 January 2018

Androgen-Independent Prostate Cancer Is a Heterogeneous Group of Diseases

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21 January 2018

Modulation of cellular and viral promoters by mutant human p53 proteins found in tumor cells

1 reference

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7 January 2021

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Carcinoma of the prostate

1 reference

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7 January 2021

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p53 Protein Accumulation and Gene Mutation in the Progression of Human Prostate Carcinoma

1 reference

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7 January 2021

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Relaxin gene and protein expression and its regulation of procollagenase and vascular endothelial growth factor in human endometrial cells

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7 January 2021

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Adenovirus-mediated expression of human prorelaxin promotes the invasive potential of canine mammary cancer cells

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7 January 2021

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Immunocytochemical identification of a relaxin-like protein in gastrointestinal epithelium and carcinoma: a preliminary report

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Human relaxins in normal, benign and neoplastic breast tissue

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Identifiers

10.1038/SJ.ONC.1209246

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

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0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

19 September 2017

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