(Q40343222)

English

Novel high-affinity PPARgamma agonist alone and in combination with paclitaxel inhibits human anaplastic thyroid carcinoma tumor growth via p21WAF1/CIP1.

scientific article published on April 2006

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16331265%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Novel high-affinity PPARgamma agonist alone and in combination with paclitaxel inhibits human anaplastic thyroid carcinoma tumor growth via p21WAF1/CIP1 (English)

1 reference

Europe PubMed Central

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10 January 2020

thyroid carcinoma

1 reference

based on heuristic

inferred from title

anaplastic thyroid carcinoma

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

2

1 reference

Europe PubMed Central

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10 January 2020

author name string

J A Copland

1

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10 January 2020

S Kurakata

3

1 reference

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10 January 2020

K Fujiwara

4

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10 January 2020

A K C Wong

5

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10 January 2020

P A Kreinest

6

1 reference

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10 January 2020

S F Williams

7

1 reference

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10 January 2020

B R Haugen

8

1 reference

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10 January 2020

J P Klopper

9

1 reference

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10 January 2020

R C Smallridge

10

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10 January 2020

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publication date

1 April 2006

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10 January 2020

1 reference

Europe PubMed Central

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10 January 2020

25

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Europe PubMed Central

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10 January 2020

16

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10 January 2020

2304-2317

1 reference

Europe PubMed Central

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10 January 2020

Treatment of anaplastic thyroid carcinoma with paclitaxel: phase 2 trial using ninety-six-hour infusion. Collaborative Anaplastic Thyroid Cancer Health Intervention Trials (CATCHIT) Group

1 reference

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7 January 2021

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Antineoplastic activity of taxol against human anaplastic thyroid carcinoma cell lines in vitro and in vivo

1 reference

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7 January 2021

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New pharmacological perspectives and therapeutic potential of PPAR-gamma agonists

1 reference

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7 January 2021

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Peroxisome proliferator-activated receptor gamma is frequently downregulated in a diversity of sporadic nonmedullary thyroid carcinomas

1 reference

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7 January 2021

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Involvement of p21 in mitotic exit after paclitaxel treatment in MCF-7 breast adenocarcinoma cell line

1 reference

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7 January 2021

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Vascular endothelial growth factor monoclonal antibody inhibits growth of anaplastic thyroid cancer xenografts in nude mice

1 reference

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7 January 2021

based on heuristic

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Modulation of in vivo growth of thyroid tumor-derived cell lines by sense and antisense vascular endothelial growth factor gene

1 reference

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7 January 2021

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Activation of PPARgamma leads to inhibition of anchorage-independent growth of human colorectal cancer cells

1 reference

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7 January 2021

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Peroxisome proliferator-activated receptor-gamma-independent inhibition of macrophage activation by the non-thiazolidinedione agonist L-796,449. Comparison with the effects of 15-deoxy-delta(12,14)-prostaglandin J(2).

1 reference

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Ciglitazone-induced cellular anti-proliferation increases p27kip1 protein levels through both increased transcriptional activity and inhibition of proteasome degradation.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Peroxisome proliferator-activated receptor gamma activation induces cell cycle arrest via the p53-independent pathway in human anaplastic thyroid cancer cells

1 reference

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7 January 2021

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Unique ability of troglitazone to up-regulate peroxisome proliferator-activated receptor-gamma expression in hepatocytes

1 reference

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7 January 2021

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The pleiotropic functions of peroxisome proliferator-activated receptor gamma

1 reference

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7 January 2021

based on heuristic

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Involvement of the PAX8/peroxisome proliferator-activated receptor gamma rearrangement in follicular thyroid tumors.

1 reference

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7 January 2021

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Peroxisome proliferator-activated receptor gamma induces pancreatic cancer cell apoptosis

1 reference

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7 January 2021

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Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice

1 reference

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7 January 2021

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Cells lacking CIP1/WAF1 genes exhibit preferential sensitivity to cisplatin and nitrogen mustard

1 reference

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7 January 2021

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Troglitazone and related compounds: therapeutic potential beyond diabetes

1 reference

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7 January 2021

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Troglitazone, a new antidiabetic agent possessing radical scavenging ability, improved decreased skin blood flow in diabetic rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

Antidiabetic thiazolidinediones inhibit invasiveness of pancreatic cancer cells via PPARgamma independent mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

PPARgamma ligands: taking Ppart in chemoprevention

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

The PAX8/PPARgamma fusion oncoprotein transforms immortalized human thyrocytes through a mechanism probably involving wild-type PPARgamma inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of peroxisome proliferator-activated receptor gamma (PPARgamma) in human transitional bladder cancer and its role in inducing cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

Up-regulation of p21 gene expression by peroxisome proliferator-activated receptor gamma in human lung carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

Peroxisome proliferator-activated receptor gamma-dependent activation of p21 in Panc-28 pancreatic cancer cells involves Sp1 and Sp4 proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

Peroxisome proliferator-activated receptor gamma-independent ablation of cyclin D1 by thiazolidinediones and their derivatives in breast cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

Ligands for peroxisome proliferator-activated receptor gamma inhibit growth of pancreatic cancers both in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

Growth inhibition and differentiation of pancreatic cancer cell lines by PPAR gamma ligand troglitazone

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeted molecular therapy of anaplastic thyroid carcinoma with AEE788.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

Peroxisome proliferator-activated receptor gamma induces growth arrest and differentiation markers of human colon cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of p21(WAF1/Cip1), p27(Kip1), and p18(INK4c) in troglitazone-induced cell-cycle arrest in human hepatoma cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

PAX8-PPARgamma1 fusion oncogene in human thyroid carcinoma [corrected]

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

Overexpression of p21(waf1) decreases G2-M arrest and apoptosis induced by paclitaxel in human sarcoma cells lacking both p53 and functional Rb protein.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The peroxisome proliferator-activated receptor gamma ligand troglitazone induces apoptosis and p53 in rat granulosa cells

1 reference

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Peroxisome proliferator-activated receptor gamma agonists promote TRAIL-induced apoptosis by reducing survivin levels via cyclin D3 repression and cell cycle arrest.

1 reference

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7 January 2021

based on heuristic

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Expression profiling reveals a distinct transcription signature in follicular thyroid carcinomas with a PAX8-PPAR(gamma) fusion oncogene.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Peroxisome proliferator activated receptor-gamma (PPAR-gamma) ligands and angiogenesis

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibitory effects of peroxisome poliferator-activated receptor gamma on thyroid carcinoma cell growth

1 reference

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7 January 2021

based on heuristic

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The PAX8/PPAR gamma fusion oncogene as a potential therapeutic target in follicular thyroid carcinoma

1 reference

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7 January 2021

based on heuristic

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Endogenous PPAR gamma mediates anti-inflammatory activity in murine ischemia-reperfusion injury

1 reference

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7 January 2021

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Role of peroxisome proliferator-activated receptor gamma and its ligands in non-neoplastic and neoplastic human urothelial cells

1 reference

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based on heuristic

inferred from DOI database lookup

Therapeutic potential of thiazolidinediones as anticancer agents

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

PPARgamma ligands inhibit primary tumor growth and metastasis by inhibiting angiogenesis

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Biochemical and cellular mechanisms of mammalian CDK inhibitors: a few unresolved issues

1 reference

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7 January 2021

based on heuristic

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Glitazones differentially regulate primary astrocyte and glioma cell survival. Involvement of reactive oxygen species and peroxisome proliferator-activated receptor-gamma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

PPARgamma : a nuclear regulator of metabolism, differentiation, and cell growth

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Peroxisome proliferator-activated receptor gamma-dependent and -independent growth inhibition of gastrointestinal tumour cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

Vascular endothelial growth factors and thyroid disorders

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential modulation of paclitaxel-mediated apoptosis by p21Waf1 and p27Kip1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

Thyroid carcinoma

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Thiazolidenediones mediate apoptosis in prostate cancer cells in part through inhibition of Bcl-xL/Bcl-2 functions independently of PPARgamma

1 reference

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7 January 2021

based on heuristic

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Opposite association of two PPARG variants with cancer: overrepresentation of H449H in endometrial carcinoma cases and underrepresentation of P12A in renal cell carcinoma cases

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Prospects for prevention and treatment of cancer with selective PPARgamma modulators (SPARMs).

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of human lung cancer cell growth by the peroxisome proliferator-activated receptor-gamma agonists through induction of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

Troglitazone acts on cellular pH and DNA synthesis through a peroxisome proliferator-activated receptor gamma-independent mechanism in breast cancer-derived cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

Antiangiogenetic therapy with pioglitazone, rofecoxib, and metronomic trofosfamide in patients with advanced malignant vascular tumors

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Loss of normal p53 function confers sensitization to Taxol by increasing G2/M arrest and apoptosis

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Angiogenesis inhibition in the in vivo antineoplastic effect of manumycin and paclitaxel against anaplastic thyroid carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

p21 Waf-1 (Cip-1) enhances apoptosis induced by manumycin and paclitaxel in anaplastic thyroid cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

Inactivation of p21WAF1/cip1 enhances intestinal tumor formation in Muc2-/- mice

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of the PPAR pathway induces apoptosis and COX-2 inhibition in HT-29 human colon cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

Troglitazone inhibits growth of MCF-7 breast carcinoma cells by targeting G1 cell cycle regulators

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

Signaling pathways involved in induction of GADD45 gene expression and apoptosis by troglitazone in human MCF-7 breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209267

7 January 2021

based on heuristic

inferred from DOI database lookup

Thiazolidinediones

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Ligands for peroxisome proliferator-activated receptor gamma have potent antitumor effect against human renal cell carcinoma

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1209267

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16331265%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16331265%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

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