(Q40354649)

English

Leptosins isolated from marine fungus Leptoshaeria species inhibit DNA topoisomerases I and/or II and induce apoptosis by inactivation of Akt/protein kinase B.

scientific article published on November 2005

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scholarly article

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Europe PubMed Central

19 September 2017

Leptosins isolated from marine fungus Leptoshaeria species inhibit DNA topoisomerases I and/or II and induce apoptosis by inactivation of Akt/protein kinase B. (English)

1 reference

Europe PubMed Central

19 September 2017

1 reference

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author name string

Miyako Yanagihara

1

1 reference

Europe PubMed Central

19 September 2017

Noriko Sasaki-Takahashi

2

1 reference

Europe PubMed Central

19 September 2017

Tetsuo Sugahara

3

1 reference

Europe PubMed Central

19 September 2017

Seiko Yamamoto

4

1 reference

Europe PubMed Central

19 September 2017

Masahito Shinomi

5

1 reference

Europe PubMed Central

19 September 2017

Izumi Yamashita

6

1 reference

Europe PubMed Central

19 September 2017

Masashi Hayashida

7

1 reference

Europe PubMed Central

19 September 2017

Banri Yamanoha

8

1 reference

Europe PubMed Central

19 September 2017

Atsushi Numata

9

1 reference

Europe PubMed Central

19 September 2017

Takao Yamori

10

1 reference

Europe PubMed Central

19 September 2017

Toshiwo Andoh

11

1 reference

Europe PubMed Central

19 September 2017

publication date

1 November 2005

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Europe PubMed Central

19 September 2017

1 reference

Europe PubMed Central

19 September 2017

96

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Europe PubMed Central

19 September 2017

11

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Europe PubMed Central

19 September 2017

816-824

1 reference

Europe PubMed Central

19 September 2017

Structure and function of type II DNA topoisomerases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00117.X

21 January 2018

Moving one DNA double helix through another by a type II DNA topoisomerase: the story of a simple molecular machine

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00117.X

21 January 2018

Antitumor activity of a novel quinoline derivative, TAS-103, with inhibitory effects on topoisomerases I and II.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00117.X

21 January 2018

Merbarone inhibits the catalytic activity of human topoisomerase IIalpha by blocking DNA cleavage

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00117.X

21 January 2018

Inhibition of DNA topoisomerases II and/or I by pyrazolo[1,5-a]indole derivatives and their growth inhibitory activities

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00117.X

21 January 2018

Retroviral expression of a mutant (Gly-533) human DNA topoisomerase I cDNA confers a dominant form of camptothecin resistance

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00117.X

21 January 2018

Isolation and characterization of kinetoplast DNA networks and minicircles from Crithidia fasciculata.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00117.X

21 January 2018

Inhibition of DNA topoisomerases by nidulalin A derivatives

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00117.X

21 January 2018

Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00117.X

21 January 2018

PI3K: downstream AKTion blocks apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00117.X

21 January 2018

Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00117.X

21 January 2018

Homocysteine induces cell cycle G1 arrest in endothelial cells through the PI3K/Akt/FOXO signaling pathway

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00117.X

21 January 2018

Optimal B-cell proliferation requires phosphoinositide 3-kinase-dependent inactivation of FOXO transcription factors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00117.X

21 January 2018

IC101 induces apoptosis by Akt dephosphorylation via an inhibition of heat shock protein 90-ATP binding activity accompanied by preventing the interaction with Akt in L1210 cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00117.X

21 January 2018

3-phosphoinositide-dependent protein kinase-1/Akt signaling represents a major cyclooxygenase-2-independent target for celecoxib in prostate cancer cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00117.X

21 January 2018

FTY720 induces apoptosis of human hepatoma cell lines through PI3-K-mediated Akt dephosphorylation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00117.X

21 January 2018

Mechanisms involved in apoptosis of human macrophages induced by lipopolysaccharide from Actinobacillus actinomycetemcomitans in the presence of cycloheximide

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00117.X

21 January 2018

Targeted disruption of the mouse topoisomerase I gene by camptothecin selection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2005.00117.X

21 January 2018

Identifiers

10.1111/J.1349-7006.2005.00117.X

1 reference

Europe PubMed Central

19 September 2017

1 reference

Europe PubMed Central

19 September 2017

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