(Q40356655)

19 September 2017

title

The survival kinase Mirk/dyrk1B is activated through Rac1-MKK3 signaling (English)

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19 September 2017

Kideok Jin

1

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19 September 2017

Seunghwan Lim

series ordinal

2

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19 September 2017

Stephen E Mercer

series ordinal

3

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19 September 2017

Eileen Friedman

series ordinal

4

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19 September 2017

language of work or name

English

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publication date

27 October 2005

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Journal of Biological Chemistry

19 September 2017

published in

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19 September 2017

volume

280

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19 September 2017

issue

51

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19 September 2017

page(s)

42097-42105

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Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance.

19 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507301200

The cyclin-dependent kinase inhibitor p27Kip1 is stabilized in G(0) by Mirk/dyrk1B kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507301200

Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507301200

The transcriptional activator Mirk/Dyrk1B is sequestered by p38alpha/beta MAP kinase

21 January 2018

1 reference

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Cadherin engagement regulates Rho family GTPases

21 January 2018

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Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock.

21 January 2018

1 reference

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Inhibition of invasion of epithelial cells by Tiam1-Rac signaling

21 January 2018

1 reference

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Interaction of Rac exchange factors Tiam1 and Ras-GRF1 with a scaffold for the p38 mitogen-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507301200

Mirk/dyrk1B is a Rho-induced kinase active in skeletal muscle differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507301200

The stress-activated protein kinases p38 alpha and JNK1 stabilize p21(Cip1) by phosphorylation

21 January 2018

1 reference

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The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

21 January 2018

1 reference

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Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

21 January 2018

1 reference

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Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

21 January 2018

1 reference

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MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

21 January 2018

1 reference

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Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A

21 January 2018

1 reference

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21 January 2018

RHO-GTPases and cancer

1 reference

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Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507301200

Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway

21 January 2018

1 reference

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Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507301200

Caspase 3-mediated inactivation of rac GTPases promotes drug-induced apoptosis in human lymphoma cells

21 January 2018

1 reference

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Rac1 inhibits apoptosis in human lymphoma cells by stimulating Bad phosphorylation on Ser-75.

21 January 2018

1 reference

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Autocrine laminin-5 ligates alpha6beta4 integrin and activates RAC and NFkappaB to mediate anchorage-independent survival of mammary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507301200

CD98hc (SLC3A2) mediates integrin signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507301200

Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507301200

Regulation of p70 S6 kinase by complex formation between the Rac guanine nucleotide exchange factor (Rac-GEF) Tiam1 and the scaffold spinophilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507301200

21 January 2018

Identifiers

DOI

10.1074/JBC.M507301200

1 reference

19 September 2017

1 reference