(Q40365020)

19 September 2017

title

Rate-limiting barriers to intestinal drug absorption: a review (English)

1 reference

19 September 2017

W L Hayton

1

1 reference

19 September 2017

publication date

1 August 1980

1 reference

Journal of Pharmacokinetics and Pharmacodynamics

19 September 2017

published in

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19 September 2017

volume

8

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19 September 2017

issue

4

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19 September 2017

page(s)

321-334

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The intestinal unstirred layer: its surface area and effect on active transport kinetics.

19 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FBF01059381

A kinetic approach to the study of absorption of solutes by isolated perfused small intestine.

21 January 2018

1 reference

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Dependence of intestinal absorption in vivo on the unstirred layer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01059381

Goblet Cell Mucin of Rat Small Intestine. Chemical and Physical Characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01059381

Experimental deficiency of gastric "mucus barrier." Its effect on gastric secretion and on the formation of acute gastric ulcer in rats infused with histamine for 24 hours

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01059381

The effect of mucin on the bioavailability of tetracycline from the gastrointestinal tract; in vivo, in vitro correlations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01059381

The influence of mucin on the bioavailability of tetracycline

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01059381

The Influence of pH, Low Sodium Ion Concentration and Methotrexate on the Jejunal-Surface pH: A Model for Folic Acid Transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01059381

Membrane Structure: Some General Principles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01059381

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01059381

On the mechanism of non-electrolyte permeation through lipid bilayers and through biomembranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01059381

Biological Membranes behave as Non-porous Polymeric Sheets with Respect to the Diffusion of Non-electrolytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01059381

Nonelectrolyte diffusion across lipid bilayer systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01059381

Reflections on general membrane structure: the conference in review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01059381

What Component of the Living Cell Is Responsible for Its Semipermeable Properties? Polarized Water or Lipids?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01059381

Membrane lipid, not polarized water, is responsible for the semipermeable properties of living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01059381

Use of Inert Gases to Study the Interaction of Blood Flow and Diffusion during Passive Absorption from the Gastrointestinal Tract of the Rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01059381

Use of inert gases and carbon monoxide to study the possible influence of countercurrent exchange on passive absorption from the small bowel

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01059381

Quantitation of countercurrent exchange during passive absorption from the dog small intestine: evidence for marked species differences in the efficiency of exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01059381

Biological Membranes: The Physical Basis of Ion and Nonelectrolyte Selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01059381

Routes of nonelectrolyte permeation across epithelial membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01059381

Unstirred layer thickness in perfused rat jejunum in vivo

21 January 2018

1 reference

12 December 2020

Bound water in biology

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12 December 2020

Use of microspheres to measure small intestinal villus blood flow in the dog

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12 December 2020

The columnar epithelial cell of the small intestine: digestion and transport. (First of three parts).

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12 December 2020

Intestinal Drug Absorption and Metabolism I: Comparison of Methods and Models to Study Physiological Factors of In Vitro and In Vivo Intestinal Absorption

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12 December 2020

Pathways for hydraulically and osmotically-induced water flows across epithelia

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12 December 2020

Determinants of intestinal mucosal uptake of short- and medium-chain fatty acids and alcohols

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12 December 2020

Intracellular water structure and mechanisms of cellular transport

1 reference

12 December 2020

Intestinal Drug Absorption and Metabolism II: Kinetic Aspects of Intestinal Glucuronide Conjugation

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12 December 2020

Tight and leaky junctions of epithelia: a perspective on kisses in the dark.

1 reference

12 December 2020

Direct measurement by pH-microelectrode of the pH microclimate in rat proximal jejunum

1 reference

12 December 2020

Size and Shape of the Lateral Intercellular Spaces in a Living Epithelium

1 reference

12 December 2020

A discrepancy between the accumulation of L-phenylalanine in the intestinal wall and the appearance rate in the blood

1 reference

12 December 2020

Intestinal Drug Absorption and Metabolism III: Glycine Conjugation and Accumulation of Benzoic Acid in Rat Intestinal Tissue

1 reference

12 December 2020

Non-electrolyte permeability across thin lipid membranes

1 reference

12 December 2020

Gut circulation and absorption: A review, Part 1

1 reference

12 December 2020

On the mechanism of intestinal absorption of drugs

1 reference

12 December 2020

Implications of two different types of diffusion for biological membranes

1 reference

12 December 2020

Factors influencing the intestinal absorption of certain monoquaternary anticholinergic compounds with special reference to benzomethamine [N-diethylaminoethyl-N'-methylbenzilamide methobromide (MC-3199)]

1 reference

12 December 2020

The influence of villous counter current exchange on intestinal absorption

1 reference

12 December 2020

Subepithelial capillary blood flow estimated from blood-to-lumen flux of barbital in ileum of rats

1 reference

12 December 2020

The influence of unstirred layers on the kinetics of carrier-mediated transport

1 reference

12 December 2020

A new model for the living cell: a summary of the theory and recent experimental evidence in its support.

1 reference

12 December 2020

Paracellular permeability of extracellular space markers across rat jejunum in vitro. Indication of a transepithelial fluid circuit

1 reference

12 December 2020

The gastric mucosal barrier: clinical and experimental studies in critically ill and normal man, and in the rabbit

1 reference

12 December 2020

Unstirred Water Layers in Intestine: Rate Determinant of Fatty Acid Absorption from Micellar Solutions

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF01059381

1 reference

19 September 2017

1 reference