(Q40372481)

19 September 2017

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title

Na+ channels as targets for neuroprotective drugs (English)

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19 September 2017

Taylor CP

1

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19 September 2017

Meldrum BS

series ordinal

2

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19 September 2017

publication date

1 September 1995

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Trends in Pharmacological Sciences

19 September 2017

published in

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19 September 2017

volume

16

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19 September 2017

issue

9

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19 September 2017

page(s)

309-316

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Active propagation of somatic action potentials into neocortical pyramidal cell dendrites

19 September 2017

cites work

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7 January 2021

Na+ currents that fail to inactivate

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7 January 2021

Cellular and molecular biology of voltage-gated sodium channels

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7 January 2021

A novel, abundant sodium channel expressed in neurons and glia

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7 January 2021

Neuroprotective effects of tetrodotoxin as a Na+ channel modulator and glutamate release inhibitor in cultured rat cerebellar neurons and in gerbil global brain ischemia

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7 January 2021

Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action

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7 January 2021

Riluzole specifically blocks inactivated Na channels in myelinated nerve fibre

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7 January 2021

The sodium channel blocker and glutamate release inhibitor BW1003C87 and magnesium attenuate regional cerebral edema following experimental brain injury in the rat

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7 January 2021

BW619C89, a glutamate release inhibitor, protects against focal cerebral ischemic damage

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7 January 2021

Zonisamide enhances slow sodium inactivation in Myxicola

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7 January 2021

Substituted 2-benzothiazolamines as sodium flux inhibitors: quantitative structure-activity relationships and anticonvulsant activity

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7 January 2021

Ralitoline (CI-946) and CI-953 block sustained repetitive sodium action potentials in cultured mouse spinal cord neurons and displace batrachotoxinin A 20-α-benzoate binding in vitro

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7 January 2021

Neuroprotective effects of carvedilol, a new antihypertensive, as a Na+ channel modulator and glutamate transport inhibitor

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7 January 2021

Na+ channels must deactivate to recover from inactivation

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7 January 2021

Pharmacological and electrographic properties of epileptiform activity induced by elevated K+ and lowered Ca2+ and Mg2+ concentration in rat hippocampal slices

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7 January 2021

Endogenous bursts underlie seizurelike activity in solitary excitatory hippocampal neurons in microcultures.

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7 January 2021

Damage from oxygen and glucose deprivation in hippocampal slices is prevented by tetrodotoxin, lidocaine and phenytoin without blockade of action potentials

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7 January 2021

Tertiary and quaternary local anesthetics protect CNS white matter from anoxic injury at concentrations that do not block excitability

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7 January 2021

The possible involvement of tetrodotoxin-sensitive ion channels in ischemic neuronal damage in the rat hippocampus

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7 January 2021

The regional vulnerability to hypoglycemia-induced neurotoxicity in organotypic hippocampal culture: protection by early tetrodotoxin or delayed MK-801.

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7 January 2021

Effects of the sodium channel blocker tetrodotoxin (TTX) on cellular ion homeostasis in rat brain subjected to complete ischemia

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7 January 2021

Cerebral cation shifts in hypoxic-ischemic brain damage are prevented by the sodium channel blocker tetrodotoxin

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7 January 2021

Lidocaine accelerates neuroelectrical recovery after incomplete global ischemia in rabbits

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7 January 2021

Comparative study of voltage-sensitive sodium channel blockers in focal ischaemia and electric convulsions in rodents

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7 January 2021

Phenytoin protects against ischemia-produced neuronal cell death

1 reference

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7 January 2021

Phenytoin reduces neonatal hypoxic-ischemic brain damage in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2989060-4

7 January 2021

Cerebroprotective effect of lamotrigine after focal ischemia in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2989060-4

7 January 2021

Neuroprotective properties of the novel antiepileptic lamotrigine in a gerbil model of global cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2989060-4

7 January 2021

Reduction of glutamate release and protection against ischemic brain damage by BW 1003C87.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2989060-4

7 January 2021

The pyrimidine-derivative, BW1003C87, protects CA1 and striatal neurons following transient severe forebrain ischaemia in rats. A microdialysis and histological study

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2989060-4

7 January 2021

Cerebroprotective effect of BW619C89 after focal or global cerebral ischaemia in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2989060-4

7 January 2021

Zonisamide reduces hypoxic-ischemic brain damage in neonatal rats irrespective of its anticonvulsive effect

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2989060-4

7 January 2021

Neuroprotective actions of riluzole in rodent models of global and focal cerebral ischaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2989060-4

7 January 2021

Effect of riluzole on focal cerebral ischemia in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2989060-4

7 January 2021

Ischemic brain damage: reduction by sodium-calcium ion channel modulator RS-87476.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2989060-4

7 January 2021

Long-term neurological assessment of the post-resuscitative effects of flunarizine, verapamil and nimodipine in a new model of global complete ischaemia.

1 reference

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7 January 2021

Flunarizine limits hypoxia-ischemia induced morphologic injury in immature rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2989060-4

7 January 2021

Neuroprotective effects of 619C89, a use-dependent sodium channel blocker, in rat traumatic brain injury

1 reference

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7 January 2021

Ionic mechanisms of anoxic injury in mammalian CNS white matter: role of Na+ channels and Na(+)-Ca2+ exchanger

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7 January 2021

A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group

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7 January 2021

The barbiturate thiopental reduces ATP levels during anoxia but improves electrophysiological recovery and ionic homeostasis in the rat hippocampal slice

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2989060-4

7 January 2021

Effect of anoxia on ion distribution in the brain

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2989060-4

7 January 2021

Perturbation of intracellular calcium and hydrogen ion regulation in cultured mouse hippocampal neurons by reduction of the sodium ion concentration gradient.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2989060-4

7 January 2021

Increased intracellular Na+ augments mobilization of Ca2+ from SR in vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2989060-4

7 January 2021

Infarct rim: effect of hyperglycemia on direct current potential and [14C]2-deoxyglucose phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2989060-4

7 January 2021

The effect of MK-801 on cortical spreading depression in the penumbral zone following focal ischaemia in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2989060-4

7 January 2021

Repeated negative DC deflections in rat cortex following middle cerebral artery occlusion are abolished by MK-801: effect on volume of ischemic injury

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2989060-4

7 January 2021

Triggering and execution of neuronal death in brain ischaemia: two phases of glutamate release by different mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2989060-4

7 January 2021

Hippocampal slices: glutamate overflow and cellular damage from ischemia are reduced by sodium-channel blockade

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2989060-4

7 January 2021

10.1016/S0165-6147(00)89060-4

Identifiers

DOI

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19 September 2017

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