(Q40375589)

19 September 2017

title

Tetracycline analogues (doxycycline and COL-3) induce caspase-dependent and -independent apoptosis in human colon cancer cells (English)

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19 September 2017

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Toshinao Onoda

1

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19 September 2017

Takashi Ono

2

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19 September 2017

Dipok Kumar Dhar

3

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19 September 2017

Akira Yamanoi

4

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19 September 2017

Naofumi Nagasue

5

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19 September 2017

language of work or name

English

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publication date

1 March 2006

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International Journal of Cancer

19 September 2017

published in

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19 September 2017

volume

118

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19 September 2017

issue

5

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19 September 2017

page(s)

1309-1315

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19 September 2017

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Doxycycline and other tetracyclines in the treatment of bone metastasis

21 January 2018

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Chemically modified tetracyclines inhibit human melanoma cell invasion and metastasis.

21 January 2018

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Cytotoxic activity and inhibition of tumor cell invasion by derivatives of a chemically modified tetracycline CMT-3 (COL-3).

21 January 2018

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Inhibition of tumor cell invasiveness by chemically modified tetracyclines

21 January 2018

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Inhibition of proliferation and induction of apoptosis by doxycycline in cultured human osteosarcoma cells

21 January 2018

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Inhibition of cell proliferation, invasion, tumor growth and metastasis by an oral non-antimicrobial tetracycline analog (COL-3) in a metastatic prostate cancer model

21 January 2018

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Chemically modified tetracyclines induce cytotoxic effects against J774 tumour cell line by activating the apoptotic pathway.

21 January 2018

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Doxycycline induces apoptosis by way of caspase-3 activation with inhibition of matrix metalloproteinase in human T-lymphoblastic leukemia CCRF-CEM cells

21 January 2018

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Doxycycline inhibits cell proliferation and invasive potential: combination therapy with cyclooxygenase-2 inhibitor in human colorectal cancer cells

21 January 2018

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The biochemistry of apoptosis

21 January 2018

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

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Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

21 January 2018

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Molecular characterization of mitochondrial apoptosis-inducing factor

21 January 2018

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Endonuclease G is an apoptotic DNase when released from mitochondria

21 January 2018

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Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

21 January 2018

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Role of AIF in caspase-dependent and caspase-independent cell death

21 January 2018

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Global cancer statistics in the year 2000.

21 January 2018

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Matrix metalloproteinases in cancer: prognostic markers and therapeutic targets.

21 January 2018

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Chemical and biological dynamics of tetracyclines.

21 January 2018

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Chemically modified tetracyclines act through multiple mechanisms directly on osteoclast precursors.

21 January 2018

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Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-x(L) in a strictly caspase-3-dependent manner in human carcinoma cells

21 January 2018

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Effects of chemically modified tetracyclines (CMTs) in sensitive, multidrug resistant and apoptosis resistant leukaemia cell lines

21 January 2018

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Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

21 January 2018

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Mitochondrial intermembrane proteins in cell death

21 January 2018

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Apoptosis-inducing factor (AIF): a ubiquitous mitochondrial oxidoreductase involved in apoptosis

21 January 2018

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Endonuclease G: a mitochondrial protein released in apoptosis and involved in caspase-independent DNA degradation.

21 January 2018

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A phase I and pharmacokinetic study of Col-3 (Metastat), an oral tetracycline derivative with potent matrix metalloproteinase and antitumor properties

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.21447

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19 September 2017

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