(Q40380727)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7495675%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

review article

1 reference

title

Immunoconjugates and immunotoxins for therapy of carcinomas (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7495675%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

author name string

Hellström I

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7495675%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

Hellström KE

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7495675%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

Siegall CB

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7495675%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

Trail PA

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7495675%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

publication date

1 January 1995

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7495675%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

published in

Advances in Pharmacology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7495675%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7495675%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

page(s)

349-388

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7495675%20AND%20SRC:MED&resulttype=core&format=json

Structure of exotoxin A of Pseudomonas aeruginosa at 3.0-Angstrom resolution

19 October 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

In vitro and in vivo efficacy of conjugates of daunomycin with anti-tumor antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

A cytotoxic agent can be generated selectively at cancer sites

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Ribosome-inactivating proteins from plants

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Antitumor activity in mice of an immunotoxin made with anti-transferrin receptor and a recombinant form of Pseudomonas exotoxin

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Single-chain immunotoxins directed at the human transferrin receptor containing Pseudomonas exotoxin A or diphtheria toxin: anti-TFR(Fv)-PE40 and DT388-anti-TFR(Fv).

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Recombinant anti-erbB2 immunotoxins containing Pseudomonas exotoxin

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Adriamycin(hydrazone)-antibody conjugates require internalization and intracellular acid hydrolysis for antitumor activity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

B3(Fv)-PE38KDEL, a single-chain immunotoxin that causes complete regression of a human carcinoma in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

A recombinant immunotoxin containing a disulfide-stabilized Fv fragment

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Unique glycoprotein-proteoglycan complex defined by monoclonal antibody on human melanoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Characterization of the human tumor and normal tissue reactivity of the KS1/4 monoclonal antibody

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Drug immunotargeting for carcinomas: a reality at last?

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Human melanoma cells can be killed in vitro by an immunotoxin specific for melanoma-associated antigen p97

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

A recombinant immunotoxin consisting of two antibody variable domains fused to Pseudomonas exotoxin

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

The crystal structure of diphtheria toxin

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Biologically active interleukin 2-ricin A chain fusion proteins may require intracellular proteolytic cleavage to exhibit a cytotoxic effect.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Monoclonal antibody C242-Pseudomonas exotoxin A. A specific and potent immunotoxin with antitumor activity on a human colon cancer xenograft in nude mice

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

1 reference

7 January 2021

Overview of radiation myelotoxicity secondary to radioimmunotherapy using 131I-Lym-1 as a model

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Cytotoxic properties of a ricin A chain immunotoxin recognising the cluster-5A antigen associated with human small-cell lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Specific immunosuppression by immunotoxins containing daunomycin

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Flow cytometric screening of monoclonal antibodies for drug or toxin targeting to human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Use of the immunotoxin N901-blocked ricin in patients with small-cell lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Preparation of four daunomycin-monoclonal antibody 791T/36 conjugates with anti-tumour activity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Preparation and properties of a drug-carrier-antibody conjugate showing selective antibody-directed cytotoxicity in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Anti-tumor antibody BR96 blocks cell migration and binds to a lysosomal membrane glycoprotein on cell surface microspikes and ruffled membranes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Phase I trial of murine monoclonal antibody L6 in breast, colon, ovarian, and lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Phase I Study of an Anti-Breast Cancer Immunotoxin by Continuous Infusion: Report of a Targeted Toxic Effect Not Predicted by Animal Studies

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Cloning, nucleotide sequence, and expression in Escherichia coli of the exotoxin A structural gene of Pseudomonas aeruginosa

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Mutations in diphtheria toxin separate binding from entry and amplify immunotoxin selectivity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Adjuvant therapy of ovarian cancer with radioactive monoclonal antibody

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Functional domains of Pseudomonas exotoxin identified by deletion analysis of the gene expressed in E. coli.

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

NAD-dependent inhibition of protein synthesis by Pseudomonas aeruginosa toxin,

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Barriers to drug delivery in solid tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Plant and fungal protein and glycoprotein toxins inhibiting eukaryote protein synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Monoclonal antibody drug conjugates for site-directed cancer chemotherapy: preclinical pharmacology and toxicology studies

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Radioimmunotherapy of B-cell lymphoma with [131I]anti-B1 (anti-CD20) antibody

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

New hydrazone derivatives of adriamycin and their immunoconjugates--a correlation between acid stability and cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Continuous cultures of fused cells secreting antibody of predefined specificity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Synthesis of site-specific methotrexate-IgG conjugates. Comparison of stability and antitumor activity with active-ester-based conjugates

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Monoclonal antibody L6-daunomycin conjugates constructed to release free drug at the lower pH of tumor tissue

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Advances in monoclonal antibody therapy of cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Diphtheria toxin: membrane interaction and membrane translocation

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Production and Characterization of Monoclonal Antibody to a Melanoma Specific Glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Immunotoxins of Pseudomonas exotoxin A (PE): effect of linkage on conjugate yield, potency, selectivity and toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Antibody conjugates with morpholinodoxorubicin and acid cleavable linkers

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

A potent and specific immunotoxin for tumor cells expressing disialoganglioside GD2

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Expression cloning of a diphtheria toxin receptor: identity with a heparin-binding EGF-like growth factor precursor

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Clinical evaluation of intraperitoneal Pseudomonas exotoxin immunoconjugate OVB3-PE in patients with ovarian cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

1 reference

7 January 2021

Recombinant toxins as novel therapeutic agents

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Comparison of four bifunctional reagents for coupling peptides to proteins and the effect of the three moieties on the immunogenicity of the conjugates

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Radiolabeled-antibody therapy of B-cell lymphoma with autologous bone marrow support

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Randomised trial of monoclonal antibody for adjuvant therapy of resected Dukes' C colorectal carcinoma. German Cancer Aid 17-1A Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

The effect of antibodies and immunotoxins reactive with HER-2/neu on growth of ovarian and breast cancer cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Disposition of a murine monoclonal antibody vinca conjugate (KS1/4-DAVLB) in patients with adenocarcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Anti-tumor effects of antibody-alkaline phosphatase conjugates in combination with etoposide phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Generation of cytotoxic agents by targeted enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Cis-aconityl spacer between daunomycin and macromolecular carriers: A model of pH-sensitive linkage releasing drug from a lysosomotropic conjugate

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Effects of methotrexate-carcinoembryonic-antigen-antibody immunoconjugates on GW-39 human tumors in nude mice

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Internalization of an intact doxorubicin immunoconjugate

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Site-specific linkage of methotrexate to monoclonal antibodies using an intermediate carrier

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Cytotoxicity of chimeric (human-murine) monoclonal antibody BR96 IgG, F(ab')2, and Fab' conjugated to Pseudomonas exotoxin

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Targeted toxins as anticancer agents

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Characterization of ribosome-inactivating proteins isolated from Bryonia dioica and their utility as carcinoma-reactive immunoconjugates

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Prevention of immunotoxin-mediated vascular leak syndrome in rats with retention of antitumor activity

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Inhibition of human renal cancer by methotrexate linked to a monoclonal antibody

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Ricin A-chain and ricin A-chain immunotoxins rapidly damage human endothelial cells: implications for vascular leak syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

In vivo efficacy of monoclonal antibody-drug conjugates of three different subisotypes which bind the human tumor-associated antigen defined by the KS1/4 monoclonal antibody

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

In vivo antitumor activity of a panel of four monoclonal antibody-vinca alkaloid immunoconjugates which bind to three distinct epitopes of carcinoembryonic antigen

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Ubiquitous cell-surface glycoprotein on tumor cells is proliferation-associated receptor for transferrin

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

The preparation of mitomycin C, adriamycin and daunomycin covalently bound to antibodies as improved cancer chemotherapeutic agents

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Clinical application of monoclonal antibody-drug conjugates for immunotargeting chemotherapy of colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Cure of xenografted human carcinomas by BR96-doxorubicin immunoconjugates

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

A covalent linkage between daunorubicin and proteins that is stable in serum and reversible by lysosomal hydrolases, as required for a lysosomotropic drug-carrier conjugate: in vitro and in vivo studies

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Anti-transferrin receptor monoclonal antibody and toxin–antibody conjugates affect growth of human tumour cells

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Preparation and in vitro cytotoxicity of a methotrexate-anti-MM46 monoclonal antibody conjugate via an oligopeptide spacer

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Immunotoxins: magic bullets or misguided missiles?

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Selective cytotoxic effects of a ricin A chain immunotoxin made with the monoclonal antibody SWA11 recognising a human small cell lung cancer antigen

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Molecular and biological properties of an abrin A chain immunotoxin designed for therapy of human small cell lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Synthesis of 1-(aminooxy)-4-[(3-nitro-2-pyridyl)dithio]butane and 1-(aminooxy)-4-[(3-nitro-2-pyridyl)dithio]but-2-ene, novel heterobifunctional cross-linking reagents

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Pseudomonas exotoxin coupled to a monoclonal antibody against ovarian cancer inhibits the growth of human ovarian cancer cells in a mouse model

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

(6-Maleimidocaproyl)hydrazone of doxorubicin--a new derivative for the preparation of immunoconjugates of doxorubicin

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Antitumor activity of some derivatives of daunorubicin at the amino and methyl ketone functions

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Doxorubicin conjugated with a monoclonal antibody directed to a human melanoma-associated proteoglycan suppresses the growth of established tumor xenografts in nude mice

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

Action of a CD24-specific deglycosylated ricin-A-chain immunotoxin in conventional and novel models of small-cell-lung-cancer xenograft

1 reference

https://api.crossref.org/works/10.1016%2FS1054-3589%2808%2960674-2

7 January 2021

10.1016/S1054-3589(08)60674-2

Identifiers

DOI

0 references

1 reference