(Q40385730)

20 September 2017

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title

Tropisetron. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential as an antiemetic (English)

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20 September 2017

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C R Lee

1

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20 September 2017

G L Plosker

series ordinal

2

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20 September 2017

D McTavish

series ordinal

3

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20 September 2017

1 November 1993

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20 September 2017

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20 September 2017

46

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20 September 2017

5

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20 September 2017

925-943

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https://scigraph.springernature.com/pub.10.2165/00003495-199346050-00009

20 September 2017

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cites work

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12 December 2020

Prevention of nausea and vomiting in cisplatin-treated patients by a selective 5-hydroxytryptamine (5-HT3) receptor antagonist, ICS 205-930.

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12 December 2020

The development of tropisetron in its clinical perspective

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12 December 2020

Efficacy of ICS 205-930, a novel 5-hydroxytryptamine3 (5-HT3) receptor antagonist, in the prevention of migraine attacks. A complex answer to a simple question. ICS 205-930 Migraine Study Group.

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Competitive interaction of agonists and antagonists with 5-HT3 recognition sites in membranes of neuroblastoma cells labelled with [3H]ICS 205-930.

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12 December 2020

5-HT3 receptor antagonists. An overview of their present status and future potential in cancer therapy-induced emesis

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The psychopharmacology of 5-HT3 receptors

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Identification and distribution of 5-HT3 receptors in rat brain using radioligand binding.

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Tropisetron in the prevention of chemotherapy-induced nausea and vomiting in patients responding poorly to previous conventional antiemetic therapy

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12 December 2020

Tropisetron. A review of the clinical experience

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12 December 2020

Emesis as a complication of cancer chemotherapy: pathophysiology, importance, and treatment

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12 December 2020

Peripherally administered serotonin 5-HT3 receptor antagonists reduce inflammatory pain in rats

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12 December 2020

Blockade of 5-hydroxytryptamine3 receptors prevents cisplatin-induced but not motion- or xylazine-induced emesis in the cat

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12 December 2020

The actions of fenfluramine and interaction with 5-HT3 receptor-antagonists to inhibit emesis in the ferret

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12 December 2020

Compassionate use of a 5-HT3-receptor antagonist, tropisetron, in patients refractory to standard antiemetic treatment

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12 December 2020

5-HT3 receptor antagonists injected into the area postrema inhibit cisplatin-induced emesis in the ferret

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12 December 2020

Tropisetron in the control of nausea and vomiting induced by combined cancer chemotherapy in children.

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12 December 2020

Changes in serotonin metabolism in cancer patients: its relationship to nausea and vomiting induced by chemotherapeutic drugs

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12 December 2020

The effect of three dose levels of ICS 205-930 (a selective 5HT-3 antagonist) on cisplatin-induced nausea and vomiting.

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12 December 2020

Tropisetron, a new 5-HT3 receptor antagonist, in the prevention of radiation-induced emesis

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12 December 2020

Preliminary evidence for the involvement of the putative 5-HT4 receptor in zacopride- and copper sulphate-induced vomiting in the ferret

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12 December 2020

Pharmacology, toxicology and human pharmacokinetics of tropisetron

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12 December 2020

Prevention of emesis by ICS 205-930 in children receiving cytotoxic chemotherapy

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12 December 2020

The 5-hydroxytryptamine receptor antagonists as antiemetics: preclinical evaluation and mechanism of action

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12 December 2020

Remission of symptoms in carcinoid syndrome with a new 5-hydroxytryptamine M receptor antagonist

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12 December 2020

Tropisetron in the prevention of chemotherapy-induced nausea and vomiting: the Nordic experience

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12 December 2020

Species variations in 5-HT3 recognition sites labeled by 3H-quipazine in the central nervous system.

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12 December 2020

Antiarrhythmic effect of a 5-hydroxytryptamine M-receptor antagonist, ICS 205-930

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12 December 2020

Influence of a specific 5-HT3 antagonist on carrageenan-induced hyperalgesia in rats.

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12 December 2020

5-HT3 receptor antagonists reverse helpless behaviour in rats

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12 December 2020

Comparison of the 5-HT3 receptor antagonist properties of ICS 205-930, GR38032F and zacopride

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12 December 2020

Fluphenazine, ICS 205-930 and dl-fenfluramine differentially antagonise drug-induced emesis in the ferret

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12 December 2020

Emesis induced by cisplatin in the ferret as a model for the detection of anti-emetic drugs

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12 December 2020

Reserpine, para-chlorophenylalanine and fenfluramine antagonise cisplatin-induced emesis in the ferret

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12 December 2020

Differential interactions of traditional and novel antiemetics with dopamine D2 and 5-hydroxytryptamine3 receptors

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12 December 2020

Tropisetron plus haloperidol to ameliorate nausea and vomiting associated with high-dose alkylating agent cancer chemotherapy

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12 December 2020

Characterization of a novel 5-HT4 receptor antagonist of the azabicycloalkyl benzimidazolone class: DAU 6285

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12 December 2020

Vagal afferent fibers and peripheral 5-HT3 receptors mediate cisplatin-induced emesis in dogs

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12 December 2020

Cisplatin induced emesis: preliminary results indicative of changes in plasma levels of 5-hydroxytryptamine

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Ondansetron and Tropisetron with Dexamethasone in the Prophylaxis of Acute Vomiting Induced by Non-cisplatin-Containing Chemotherapy

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12 December 2020

Identification of serotonin M-receptor subtypes and their specific blockade by a new class of drugs.

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12 December 2020

Efficacy and tolerability of tropisetron and dexamethasone in the control of nausea and vomiting induced by cisplatin

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12 December 2020

The abdominal visceral innervation and the emetic reflex: pathways, pharmacology, and plasticity

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12 December 2020

A primer on geriatric psychopharmacology

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12 December 2020

5-hydroxytryptamine3 receptors in the human brain: autoradiographic visualization using [3H]ICS 205-930.

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12 December 2020

Antiemetic efficacy of high-dose metoclopramide: randomized trials with placebo and prochlorperazine in patients with chemotherapy-induced nausea and vomiting

1 reference

12 December 2020

Pharmacokinetics and metabolism of the 5-hydroxytryptamine antagonist tropisetron after single oral doses in humans

1 reference

12 December 2020

[3H]ICS 205-930 labels 5-HT3 recognition sites in membranes of cat and rabbit vagus nerve and superior cervical ganglion

1 reference

12 December 2020

Dose-ranging antiemetic evaluation of the serotonin antagonist tropisetron in patients receiving anti-cancer chemotherapy

1 reference

12 December 2020

Three years' experience with tropisetron in the control of nausea and vomiting in cisplatin-treated patients

1 reference

12 December 2020

Selective blockade of cytotoxic drug-induced emesis by 5-HT3 receptor antagonists in Suncus murinus

1 reference

12 December 2020

First results with ICS 205-930 (5-HT3 receptor antagonist) in prevention of chemotherapy-induced emesis

1 reference

12 December 2020

Improved control of cisplatin-induced emesis with high-dose metoclopramide and with combinations of metoclopramide, dexamethasone, and diphenhydramine. Results of consecutive trials in 255 patients.

1 reference

12 December 2020

10.2165/00003495-199346050-00009

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DOI

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20 September 2017

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