(Q40387180)

20 September 2017

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title

Leukotrienes as a target in asthma therapy (English)

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20 September 2017

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N Chanarin

1

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PubMed ID

7510618

20 September 2017

S L Johnston

series ordinal

2

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20 September 2017

1 January 1994

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20 September 2017

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20 September 2017

47

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20 September 2017

1

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20 September 2017

12-24

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https://scigraph.springernature.com/pub.10.2165/00003495-199447010-00002

20 September 2017

0 references

cites work

Enhanced leukotriene synthesis in leukocytes of atopic and asthmatic subjects

1 reference

12 December 2020

Platelet-activating factor as a mediator of allergic disease

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12 December 2020

Inhaled corticosteroids reduce the severity of bronchial hyperresponsiveness in asthma but oral theophylline does not.

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12 December 2020

Time course of change in bronchial reactivity with an inhaled corticosteroid in asthma

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12 December 2020

Bronchial hyperreactivity to leucotriene D4 and histamine in exogenous asthma

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12 December 2020

Pharmacological study of the contractile activity of leukotriene C4 and D4 on isolated human airway smooth muscle.

1 reference

12 December 2020

Inhibition of exercise-induced bronchoconstriction by MK-571, a potent leukotriene D4-receptor antagonist

1 reference

12 December 2020

Pharmacology of peptide leukotriene receptor antagonists

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12 December 2020

Mucosal inflammation in asthma

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12 December 2020

Differential effects of calcium channel blockers on leukotriene C4- and D4-induced contractions in guinea pig pulmonary parenchymal strips.

1 reference

12 December 2020

Role of leukotrienes in exercise-induced asthma. Inhibitory effect of ICI 204219, a potent leukotriene D4 receptor antagonist

1 reference

12 December 2020

Nebulization and selective deposition of LTD4in human lungs

1 reference

12 December 2020

Effects of leukotrienes C4 and D4 on glycoprotein and lysozyme secretion by human bronchial mucosa

1 reference

12 December 2020

Effects of leukotriene D on the airways in asthma

1 reference

12 December 2020

Effects of a thromboxane synthetase inhibitor (OKY-046) and a lipoxygenase inhibitor (AA-861) on bronchial responsiveness to acetylcholine in asthmatic subjects

1 reference

12 December 2020

The effect of an oral leukotriene antagonist L-649,923 on histamine and leukotriene D4-induced bronchoconstriction in normal man.

1 reference

12 December 2020

Pharmacological profile of leukotrienes E4, N-acetyl E4 and of four of their novel omega- and beta-oxidative metabolites in airways of guinea-pig and man in vitro

1 reference

12 December 2020

Airway responsiveness to leukotrienes C4 and D4 and to methacholine in patients with asthma and normal controls

1 reference

12 December 2020

1 reference

12 December 2020

Leukotrienes and airway responses.

1 reference

12 December 2020

Antagonism of antigen-induced contraction of guinea pig and human airways

1 reference

12 December 2020

Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation

1 reference

12 December 2020

Bronchodilator properties of an inhaled leukotriene D4 antagonist (verlukast—MK-0679) in asthmatic patients

1 reference

12 December 2020

Lung function improvement in asthma with a cysteinylleukotriene receptor antagonist

1 reference

12 December 2020

Perspectives in platelet-activating factor research

1 reference

12 December 2020

Urinary Excretion of Leukotriene E4and 11-dehydro-Thromboxane B2in Response to Bronchial Provocations with Allergen, Aspirin, Leukotriene D4, and Histamine in Asthmatics

1 reference

12 December 2020

Liberation of histamine and formation of lysocithin-like substances by cobra venom

1 reference

12 December 2020

Effect of a leukotriene antagonist, ONO-1078, on bronchial hyperresponsiveness in patients with asthma

1 reference

12 December 2020

The effects of a 5-lipoxygenase inhibitor on asthma induced by cold, dry air

1 reference

12 December 2020

Comparison of a beta 2-agonist, terbutaline, with an inhaled corticosteroid, budesonide, in newly detected asthma

1 reference

12 December 2020

Urinary leukotriene E4 excretion in exercise-induced asthma

1 reference

12 December 2020

Leukotriene D4 receptor blockade inhibits the immediate and late bronchoconstrictor responses to inhaled antigen in patients with asthma

1 reference

12 December 2020

Slow-reacting substances, leukotrienes C4 and D4, increase the release of mucus from human airways in vitro

1 reference

12 December 2020

Prevention of exercise-induced bronchoconstriction by a new leukotriene antagonist (SK&F 104353). A double-blind study versus disodium cromoglycate and placebo

1 reference

12 December 2020

Comparative effects of inhaled leukotriene C4, leukotriene D4, and histamine in normal human subjects

1 reference

12 December 2020

Leukotriene-C4 enhances mucus production from submucosal glands in canine trachea in vivo

1 reference

12 December 2020

Recovery of Leukotriene E4from the Urine of Patients with Airway Obstruction

1 reference

12 December 2020

Effect of the leukotriene receptor antagonist MK-0679 on baseline pulmonary function in aspirin sensitive asthmatic subjects

1 reference

12 December 2020

Release of leukotrienes in patients with bronchial asthma

1 reference

12 December 2020

Reduced nonspecific bronchial reactivity and decreased airway response to antigen challenge in atopic asthmatic patients treated with the inhaled leukotriene D4 antagonist, L‐648,051

1 reference

12 December 2020

Comparative studies of human basophils and mast cells

1 reference

12 December 2020

Bronchoconstrictor effects of leukotriene E4 in normal and asthmatic subjects

1 reference

12 December 2020

Generation and metabolism of 5-lipoxygenase pathway leukotrienes by human eosinophils: predominant production of leukotriene C4.

1 reference

12 December 2020

Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes

1 reference

12 December 2020

Effect of cysteinyl-leukotriene receptor antagonist ICI 204.219 on allergen-induced bronchoconstriction and airway hyperreactivity in atopic subjects

1 reference

12 December 2020

Local effects of synthetic leukotrienes (LTC4, LTD4, LTE4, and LTB4) in human skin

1 reference

12 December 2020

Bronchoalveolar neutrophilia during late asthmatic reactions induced by toluene diisocyanate

1 reference

12 December 2020

SLOW-REACTING SUBSTANCE OF ANAPHYLAXIS ANTAGONIST FPL 55712 IN CHRONIC ASTHMA

1 reference

12 December 2020

Characterization of inflammatory mediator release from purified human lung mast cells

1 reference

12 December 2020

Pharmacology of MK-0591 (3-[1-(4-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-yl-methoxy)- indol-2-yl]-2,2-dimethyl propanoic acid), a potent, orally active leukotriene biosynthesis inhibitor

1 reference

12 December 2020

Responses of human skin to intradermal injection of leukotrienes C4, D4 and B4.

1 reference

12 December 2020

Effect of a leukotriene antagonist, LY171883, on cold air-induced bronchoconstriction in asthmatics

1 reference

12 December 2020

Effect of a platelet activating factor antagonist, WEB 2086, on allergen induced asthmatic responses

1 reference

12 December 2020

The potential roles of leukotrienes in bronchial asthma

1 reference

12 December 2020

Leukotriene antagonists and inhibitors as modulators of IgE-mediated reactions

1 reference

12 December 2020

Effect of the oral leukotriene D4 antagonist LY171883 on inhaled and intradermal challenge with antigen and leukotriene D4 in atopic subjects

1 reference

12 December 2020

Leukotrienes, LTC4 and LTB4, in bronchoalveolar lavage in bronchial asthma and other respiratory diseases

1 reference

12 December 2020

Bronchoconstriction produced in man by leukotrienes C and D

1 reference

12 December 2020

Effect of inhaled piriprost (U-60, 257) a novel leukotriene inhibitor, on allergen and exercise induced bronchoconstriction in asthma

1 reference

12 December 2020

The effect of an oral leukotriene D4 antagonist L-649,923 on the response to inhaled antigen in asthma.

1 reference

12 December 2020

Synthesis and release of leukotriene C4 by human eosinophils

1 reference

12 December 2020

Plasma levels of leukotrienes C4 and D4 during wheezing attack in asthmatic patients

1 reference

12 December 2020

Bronchoalveolar lavage of allergic asthmatic patients following allergen bronchoprovocation.

1 reference

12 December 2020

A specific LTD4/LTE4-receptor antagonist improves pulmonary function in patients with mild, chronic asthma

1 reference

12 December 2020

The protective effect of inhaled leukotriene D4 receptor antagonist ICI 204,219 against exercise-induced asthma

1 reference

12 December 2020

Regional and time-dependent effects of inflammatory mediators on airway microvascular permeability in the guinea pig.

1 reference

12 December 2020

Leukotrienes are potent constrictors of human bronchi

1 reference

12 December 2020

Leukotriene generation by eosinophils

1 reference

12 December 2020

Comparative contractile responses to sulfidopeptide leukotrienes in normal and asthmatic human subjects

1 reference

12 December 2020

Complement receptor enhancement and chemotaxis of human neutrophils and eosinophils by leukotrienes and other lipoxygenase products

1 reference

12 December 2020

10.2165/00003495-199447010-00002

Identifiers

DOI

1 reference

PubMed ID

7510618

Dimensions Publication ID

20 September 2017

0 references

1 reference

PubMed ID

7510618