(Q40393393)

20 September 2017

1 reference

title

The genetic basis of autoimmune disease in MRL-lpr/lpr mice (English)

1 reference

20 September 2017

The Genetic Basis of Autoimmune Disease in MRL-lpr/lpr Mice (English)

1 reference

https://api.crossref.org/works/10.3109/08830189409061726

16 May 2024

1 reference

A. Shirai

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7523550

16 May 2024

D. M. Klinman

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7523550

16 May 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7523550

16 May 2024

publication date

1 January 1994

1 reference

full work available at URL

20 September 2017

http://www.tandfonline.com/doi/pdf/10.3109/08830189409061726

1 reference

https://api.crossref.org/works/10.3109/08830189409061726

International Reviews of Immunology

16 May 2024

published in

1 reference

20 September 2017

volume

11

1 reference

20 September 2017

issue

3

1 reference

20 September 2017

page(s)

179-192

1 reference

Speculations on Mechanisms of HLA Associations with Autoimmune Diseases and the Specificity of "Autoreactive" T Lymphocytes

20 September 2017

cites work

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Genetic studies in NZB mice. V. Recombinant inbred lines demonstrate that separate genes control autoimmune phenotype

21 January 2018

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Genetic and immunological mechanisms in the pathogenesis of systemic lupus erythematosus

21 January 2018

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A new allele of the lpr locus, lprcg, that complements the gld gene in induction of lymphadenopathy in the mouse

21 January 2018

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A new mutation, gld, that produces lymphoproliferation and autoimmunity in C3H/HeJ mice

21 January 2018

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Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease

21 January 2018

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Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease

21 January 2018

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Autoimmune accelerating genes, lpr and Yaa, in murine systemic lupus erythematosus

21 January 2018

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The lymphoproliferating cells of MRL-lpr/lpr mice are a polyclonal population that bear the T lymphocyte receptor for antigen

21 January 2018

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Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

21 January 2018

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A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor

21 January 2018

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Aberrant transcription caused by the insertion of an early transposable element in an intron of the Fas antigen gene of lpr mice

21 January 2018

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Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci

21 January 2018

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The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

21 January 2018

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The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane

21 January 2018

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Germinal center cells express bcl-2 protein after activation by signals which prevent their entry into apoptosis

21 January 2018

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Bcl-2: a repressor of lymphocyte death

21 January 2018

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bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

21 January 2018

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Studies of twins with systemic lupus erythematosus. A review of the literature and presentation of 12 additional sets

21 January 2018

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The contribution of NZW genes to lupus-like disease in (NZB x NZW)F1 mice

21 January 2018

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HLA-DQ gene complementation and other histocompatibility relationships in man with the anti-Ro/SSA autoantibody response of systemic lupus erythematosus

21 January 2018

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Association between a T cell receptor restriction fragment length polymorphism and systemic lupus erythematosus

21 January 2018

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Stochastic control of anti-Sm autoantibodies in MRL/Mp-lpr/lpr mice

21 January 2018

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Induction of severe autoimmune disease in normal mice by simultaneous action of multiple immunostimulators

21 January 2018

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Induction of murine autoimmune disease by chronic polyclonal B cell activation

21 January 2018

1 reference

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The lpr gene causes an intrinsic T cell abnormality that is required for hyperproliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189409061726

Influence of thymic genotype on the systemic lupus erythematosus-like disease and T cell proliferation of MRL/Mp-lpr/lpr mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189409061726

The contribution of L3T4+ T cells to lymphoproliferation and autoantibody production in MRL-lpr/lpr mice

21 January 2018

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B-cell stimulatory factor-1/interleukin 4.

21 January 2018

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Molecular regulation of B lymphocyte response

21 January 2018

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Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

21 January 2018

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The abnormal T lymphocytes in lpr mice transcribe interferon-gamma and tumor necrosis factor-alpha genes spontaneously in vivo

21 January 2018

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Synovium as a source of interleukin 6 in vitro. Contribution to local and systemic manifestations of arthritis

21 January 2018

1 reference

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In vivo cytokine gene expression in T cell subsets of the autoimmune MRL/Mp-lpr/lpr mouse

21 January 2018

1 reference

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Dysregulated expression of the T cell cytokine Eta-1 in CD4-8- lymphocytes during the development of murine autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189409061726

Identification of a B cell differentiation factor(s) spontaneously produced by proliferating T cells in murine lupus strains of the lpr/lpr genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189409061726

Characterization of functional T-cell lines derived from MRL mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189409061726

Deletion of potentially self-reactive T cell receptor specificities in L3T4-, Lyt-2- T cells of lpr mice

21 January 2018

1 reference

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Possible role of V beta T cell receptor genes in susceptibility to collagen-induced arthritis in mice

21 January 2018

1 reference

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Defect in negative selection in lpr donor-derived T cells differentiating in non-lpr host thymus

21 January 2018

1 reference

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Defective maintenance of T cell tolerance to a superantigen in MRL-lpr/lpr mice

21 January 2018

1 reference

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Reduction of lupus nephritis in MRL/lpr mice by a bacterial superantigen treatment

21 January 2018

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Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide

21 January 2018

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T-cell regulation of antibody responses: demonstration of allotype-specific helper T cells and their specific removal by suppressor T cells

21 January 2018

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Selective suppression of retroviral gp70-anti-gp70 immune complex formation by prostaglandin E1 in murine systemic lupus erythematosus

21 January 2018

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An intrinsic B cell defect is required for the production of autoantibodies in the lpr model of murine systemic autoimmunity

21 January 2018

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Receptor editing: an approach by autoreactive B cells to escape tolerance

21 January 2018

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Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse

21 January 2018

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The molecular origin of anti-DNA antibodies.

21 January 2018

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Pathogenic subsets of antibodies to DNA.

21 January 2018

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Somatic mutations in the variable regions of a human IgG anti-double-stranded DNA autoantibody suggest a role for antigen in the induction of systemic lupus erythematosus

21 January 2018

1 reference

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Systemic autoimmune disease arises from polyclonal B cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189409061726

Polyclonal B cell activation in lupus-prone mice precedes and predicts the development of autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189409061726

Theoretical and experimental approaches to generalized autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189409061726

A human protein specific for the immunoglobulin octamer DNA motif contains a functional homeobox domain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189409061726

Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis. Possible role in expansion of the mesangial extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189409061726

Chromosomal localization of seven members of the murine TGF-beta superfamily suggests close linkage to several morphogenetic mutant loci

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830189409061726

Analysis of thymic endogenous retroviral expression in murine lupus. Genetic and immune studies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189409061726

Antigen nonspecific effect of major histocompatibility complex haplotype on autoantibody levels in systemic lupus erythematosus-prone lpr mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189409061726

Effect of polymorphism of an MHC-linked transporter on the peptides assembled in a class I molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189409061726

Genetic elements used for a murine lupus anti-DNA autoantibody are closely related to those for antibodies to exogenous antigens

21 January 2018

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T-cell receptor V beta repertoire expression in murine models of SLE.

21 January 2018

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Transcriptional Repression and Differential Splicing of Fas m-RNA by Early Transposon (ETn) Insertion in Autoimmune LPR Mice

21 January 2018

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Autoimmune disease in mice due to integration of an endogenous retrovirus in an apoptosis gene

21 January 2018

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https://api.crossref.org/works/10.3109%2F08830189409061726

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830189409061726

Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice

21 January 2018

1 reference

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The role of clonal selection and somatic mutation in autoimmunity

21 January 2018

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Autoimmune diseases: the failure of self tolerance

21 January 2018

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A strong association between the antinuclear antibody anti-La (SS-B) and the kappa chain allotype Km(1)

16 May 2024

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NIH conference. Systemic lupus erythematosus

16 May 2024

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Interaction of mutant lpr gene with background strain influences renal disease

16 May 2024

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Genetic control of inflammatory arthritis and glomerulonephritis in congenic lpr mice and their F1 hybrids

16 May 2024

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A molecular genetic linkage map of mouse chromosome 19, including thelpr, Ly-44, andTdt genes

16 May 2024

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Studies in familial systemic lupus erythematosus

16 May 2024

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Studies of relatives of patients with systemic lupus erythematosus

16 May 2024

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ANTINUCLEAR FACTOR IN SYSTEMIC LUPUS ERYTHEMATOSUS. A CONSIDERATION OF THE IMMUNOFLUORESCENT METHOD OF DETECTING ANTINUCLEAR ANTIBODIES, WITH RESULTS OBTAINED IN A FAMILY STUDY

16 May 2024

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Effect of total lymphoid irradiation on levels of serum autoantibodies in systemic lupus erythematosus and in rheumatoid arthritis

16 May 2024

35

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Associations between systemic lupus erythematosus and the major histocompatibility complex: clinical and immunological considerations

16 May 2024

41

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Interaction of mutant lpr gene with background strain influences renal disease

16 May 2024

45

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The role of L3T4+ cells in the pathogenesis of lupus in lpr-bearing mice. I. Defects in the production of interleukins 2 and 3

16 May 2024

60

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Age-associated increase in interleukin 6 in MRL/lpr mice

16 May 2024

74

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Proceedings of the National Academy of Sciences of the United States of America

16 May 2024

83

83

7017

Singer P. A.

1986

1 reference

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lpr T cells vaccinate against lupus in MRL/lpr mice

16 May 2024

91

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Etiopathogenesis of the rheumatoid arthritis-like disease in MRL/l mice. I. The histomorphologic basis of joint destruction

16 May 2024

114

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A molecular genetic linkage map of mouse chromosome 7

16 May 2024

117

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Macrophage I-A/I-E expression and macrophage-stimulating lymphokines in murine lupus

16 May 2024

120

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Molecular analysis of the murine lupus-associated anti-self response: involvement of a large number of heavy and light chain variable region genes

16 May 2024

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16 May 2024

Apoptosis

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16 May 2024

Identifiers

1 reference

20 September 2017

1 reference