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Parkinson's disease-associated mutations in DJ-1 modulate its dimerization in living cells.
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scholarly article
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stated in
Europe PubMed Central
PMC publication ID
3644405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23183826%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 February 2020
title
Parkinson's disease-associated mutations in DJ-1 modulate its dimerization in living cells
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3644405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23183826%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 February 2020
main subject
Parkinson's disease
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inferred from title
author
Francisco J. Enguita
series ordinal
4
1 reference
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Europe PubMed Central
PMC publication ID
3644405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23183826%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 February 2020
Mariaelena Repici
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
3644405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23183826%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 February 2020
Kornelis Straatman
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2
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Europe PubMed Central
PMC publication ID
3644405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23183826%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 February 2020
Tiago Fleming Outeiro
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5
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Europe PubMed Central
PMC publication ID
3644405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23183826%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 February 2020
author name string
Nadia Balduccio
series ordinal
3
1 reference
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Europe PubMed Central
PMC publication ID
3644405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23183826%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 February 2020
Flaviano Giorgini
series ordinal
6
1 reference
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Europe PubMed Central
PMC publication ID
3644405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23183826%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 February 2020
publication date
27 November 2012
1 reference
stated in
Europe PubMed Central
PMC publication ID
3644405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23183826%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 February 2020
published in
Journal of Molecular Medicine
1 reference
stated in
Europe PubMed Central
PMC publication ID
3644405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23183826%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 February 2020
volume
91
1 reference
stated in
Europe PubMed Central
PMC publication ID
3644405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23183826%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 February 2020
issue
5
1 reference
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Europe PubMed Central
PMC publication ID
3644405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23183826%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 February 2020
page(s)
599-611
1 reference
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Europe PubMed Central
PMC publication ID
3644405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23183826%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 February 2020
exact match
https://scigraph.springernature.com/pub.10.1007/s00109-012-0976-y
0 references
cites work
Autosomal recessive parkinsonism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
What genetics tells us about the causes and mechanisms of Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
Recent advances in the genetics of Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
L10p and P158DEL DJ-1 mutations cause protein instability, aggregation, and dimerization impairments
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
Features and development of Coot
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
DJ-1, PINK1, and their effects on mitochondrial pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
Oxidizable residues mediating protein stability and cytoprotective interaction of DJ-1 with apoptosis signal-regulating kinase 1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
VASCo: computation and visualization of annotated protein surface contacts.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
Crystal Structure of Filamentous Aggregates of Human DJ-1 Formed in an Inorganic Phosphate-dependent Manner
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
Molecular basis for the structural instability of human DJ-1 induced by the L166P mutation associated with Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
Structural effects of Parkinson's disease linked DJ-1 mutations.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
On the oligomeric state of DJ-1 protein and its mutants associated with Parkinson Disease. A combined computational and in vitro study.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
Design and implementation of bimolecular fluorescence complementation (BiFC) assays for the visualization of protein interactions in living cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
Effects of DJ-1 mutations and polymorphisms on protein stability and subcellular localization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
Novel homozygous p.E64D mutation in DJ1 in early onset Parkinson disease (PARK7).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
A missense mutation (L166P) in DJ-1, linked to familial Parkinson's disease, confers reduced protein stability and impairs homo-oligomerization.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
Differential Effects of Parkinson's Disease-associated Mutations on Stability and Folding of DJ-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
The 1.1-A resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
The crystal structure of DJ-1, a protein related to male fertility and Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
Crystal structure of human DJ-1, a protein associated with early onset Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
Simultaneous visualization of multiple protein interactions in living cells using multicolor fluorescence complementation analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
22 September 2017
HotPatch: a statistical approach to finding biologically relevant features on protein surfaces
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
17 June 2018
Reduced anti-oxidative stress activities of DJ-1 mutants found in Parkinson's disease patients
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
17 June 2018
Mechanisms of DJ-1 neuroprotection in a cellular model of Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
20 August 2018
Pathological properties of the Parkinson's disease-associated protein DJ-1 in alpha-synucleinopathies and tauopathies: relevance for multiple system atrophy and Pick's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
20 August 2018
Familial Parkinson's disease-associated L166P mutation disrupts DJ-1 protein folding and function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
20 August 2018
The DJ-1L166P mutant protein associated with early onset Parkinson's disease is unstable and forms higher-order protein complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
20 August 2018
Visualization of Protein Interactions in Living Cells Using Bimolecular Fluorescence Complementation (BiFC) Analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3644405
retrieved
2 December 2018
Structural determinants of the C-terminal helix-kink-helix motif essential for protein stability and survival promoting activity of DJ-1
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23183826
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Destabilization of DJ-1 by familial substitution and oxidative modifications: implications for Parkinson's disease
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23183826
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
DJ-1( PARK7), a novel gene for autosomal recessive, early onset parkinsonism
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23183826
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1007/S00109-012-0976-Y
1 reference
stated in
Europe PubMed Central
PMC publication ID
3644405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23183826%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 February 2020
PMC publication ID
3644405
1 reference
stated in
Europe PubMed Central
PMC publication ID
3644405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23183826%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 February 2020
PubMed publication ID
23183826
1 reference
stated in
Europe PubMed Central
PMC publication ID
3644405
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23183826%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 February 2020
ResearchGate publication ID
233765598
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