(Q40397753)

English

Fludarabine phosphate. A new anticancer drug with significant activity in patients with chronic lymphocytic leukemia and in patients with lymphoma

scientific article published on January 1994

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

1 reference

Europe PubMed Central

Fludarabine phosphate. A new anticancer drug with significant activity in patients with chronic lymphocytic leukemia and in patients with lymphoma (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

0 references

chronic lymphocytic leukemia

1 reference

based on heuristic

inferred from title

author name string

G Rodriguez

1

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

publication date

1 January 1994

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Investigational New Drugs

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

12

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

75-92

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

https://scigraph.springernature.com/pub.10.1007/bf00874436

0 references

Purinogenic Immunodeficiency Diseases: Clinical Features and Molecular Mechanisms

1 reference

https://api.crossref.org/works/10.1007%2FBF00874436

21 January 2018

2'-Deoxycoformycin (pentostatin) for lymphoid malignancies. Rational development of an active new drug

1 reference

https://api.crossref.org/works/10.1007%2FBF00874436

21 January 2018

Fludarabine phosphate for the treatment of low grade lymphoid malignancy

1 reference

https://api.crossref.org/works/10.1007%2FBF00874436

21 January 2018

Reversible neurologic toxicity in patients treated with standard-dose fludarabine phosphate for mycosis fungoides and chronic lymphocytic leukemia.

1 reference

https://api.crossref.org/works/10.1007%2FBF00874436

21 January 2018

Kinetic considerations for the regulation of adenosine and deoxyadenosine metabolism in mouse and human tissues based on a thymocyte model.

1 reference

https://api.crossref.org/works/10.1007%2FBF00874436

21 January 2018

Guidelines for clinical protocols for chronic lymphocytic leukemia: recommendations of the National Cancer Institute-sponsored working group

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II study of fludarabine phosphate in multiple myeloma. A Southwest Oncology Group study

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II study of fludarabine phosphate (NSC 312887) in patients with advanced cervical cancer. A Southwest Oncology Group study

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II study of fludarabine phosphate for the treatment of advanced non-small cell carcinoma of the lung: a Southwest Oncology Group Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II study of fludarabine phosphate (NSC-312887) in patients with advanced ovarian cancer. A Southwest Oncology Group Study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II trial of fludarabine phosphate (F-Ara-AMP) in patients with advanced breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II trial of fludarabine phosphate in advanced renal cell carcinoma: an Illinois Cancer Council Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro biological activity of 9-beta-D-arabinofuranosyl-2-fluoroadenine and the biochemical actions of its triphosphate on DNA polymerases and ribonucleotide reductase from HeLa cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Has the well gone dry? The First Cain Memorial Award Lecture.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fludarabine phosphate (NSC 312878) infusions for the treatment of acute leukemia: phase I and neuropathological study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism and therapeutic efficacy of 9-beta-D-arabinofuranosyl-2-fluoroadenine against murine leukemia P388

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II trial of fludarabine in patients with epithelial ovarian cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II study of fludarabine phosphate (NSC-312887) in patients with advanced endometrial cancer. A Southwest Oncology Group Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of fludarabine, a new adenine nucleoside analogue, in patients with prolymphocytic leukemia and the prolymphocytoid variant of chronic lymphocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity of systems mediating transport of adenosine, 9-beta-d-arabinofuranosyl-2-fluoroadenine, and other purine nucleoside analogues in L1210 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the toxicity and metabolism of 9-beta-D-arabinofuranosyl-2-fluoroadenine and 9-beta-D-arabinofuranosyladenine in human lymphoblastoid cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biologic activity of 9-β-d-arabinofuranosyl-2-fluoroadenine, a metabolically stable analog of 9-β-d-arabinofuranosyladenine

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacology of fludarabine phosphate after a phase I/II trial by a loading bolus and continuous infusion in pediatric patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of fludarabine phosphate in patients with recurrent glioma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the actions of 9-beta-D-arabinofuranosyl-2-fluoroadenine and 9-beta-D-arabinofuranosyladenine on target enzymes from mouse tumor cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I and II study of fludarabine phosphate in leukemia: therapeutic efficacy with delayed central nervous system toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central nervous system toxicity with fludarabine

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II trial of fludarabine phosphate in lymphoma: an effective new agent in low-grade lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of fludarabine phosphate in small cell carcinoma. A Southwest Oncology Group Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I study of fludarabine (2-fluoro-ara-AMP).

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of advanced chronic lymphocytic leukemia by fludarabine

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Termination of DNA synthesis by 9-beta-D-arabinofuranosyl-2-fluoroadenine. A mechanism for cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I clinical investigation of fludarabine phosphate by a loading-dose and continuous-infusion schedule

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disposition of 9-beta-D-arabinofuranosyl-2-fluoroadenine 5'-phosphate in mice and dogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II trial of fludarabine phosphate in patients with head and neck cancer: a Southwest Oncology Group Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fludarabine therapy in hairy cell leukemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A loading dose/continuous infusion schedule of fludarabine phosphate in chronic lymphocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fludarabine therapy in macroglobulinemic lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II evaluation of fludarabine in patients with metastatic breast cancer: a Southeastern Cancer Study Group trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity of Fludarabine Monophosphate in Patients With Advanced Mycosis Fungoides: A Southwest Oncology Group Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fludarabine therapy in Waldenström's macroglobulinemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II evaluation of fludarabine phosphate in patients with central nervous system tumors. A Southwest Oncology Group trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleosides of 2-Fluoroadenine

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fludarabine: a new agent with major activity against chronic lymphocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I clinical investigation of 9-beta-D-arabinofuranosyl-2-fluoroadenine 5'-monophosphate (NSC 312887), a new purine antimetabolite

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic study of fludarabine phosphate (NSC 312887)

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deoxycytidine kinase from calf thymus. Substrate and inhibitor specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacodynamics and proposed mechanism of therapeutic action and host toxicity of 9-beta-D-arabinofuranosyl-2-fluoroadenine monophosphate (F-araAMP) in P388 murine leukemia-bearing mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comprehensive phase I and II clinical investigation of fludarabine phosphate

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II trial of fludarabine phosphate (F-ara-AMP) in patients with advanced head and neck cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies of 9-beta-D-arabinofuranosyladenine in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central nervous system toxicity of fludarabine phosphate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pulmonary toxicity associated with fludarabine monophosphate

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Current approaches to the chemotherapy of B-cell chronic lymphocytic leukemia: a review

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II trial of 9-beta-D-arabinofuranosyl-2-fluoroadenine 5'-monophosphate in non-Hodgkin's lymphoma: prospective comparison of response with deoxycytidine kinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fludarabine phosphate therapy of non-Hodgkin's lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analogs of 2'-deoxyadenosine: facile enzymatic preparation and growth inhibitory effects on human cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of fludarabine phosphate in renal cell carcinoma: a Southwest Oncology Group Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the biologic activity of purine and pyrimidine analogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I clinical trial of fludarabine phosphate (F-ara-AMP).

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxic activity of 9-beta-D-arabinofuranosyl-2-fluoroadenine 5-monophosphate (fludarabine, NSC 312887) in a human tumor cloning system

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism and chemotherapeutic activity of 9-beta-D-arabinofuranosyl-2-fluoroadenine against murine leukemia L1210 and evidence for its phosphorylation by deoxycytidine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II study of fludarabine phosphate in previously untreated patients with colorectal carcinoma: a Southwest Oncology Group Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine-deaminase deficiency in two patients with severely impaired cellular immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of fludarabine phosphate in malignant melanoma. A Southwest Oncology Group study

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fludarabine phosphate. Phase II evaluation in advanced soft-tissue sarcomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II study of fludarabine phosphate in patients with advanced colorectal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II study of fludarabine phosphate in previously untreated patients with hepatoma: a Southwest Oncology Group Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incorporation of 9-beta-D-arabinofuranosyl-2-fluoroadenine into HL-60 cellular RNA and DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism and action of fludarabine phosphate

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects on human peripheral lymphocytes of in vivo administration of 9-beta-D-arabinofuranosyl-2-fluoroadenine-5'-monophosphate (NSC 312887), a new purine antimetabolite

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-fluoro-ATP: a toxic metabolite of 9-beta-D-arabinosyl-2-fluoroadenine

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Letter: Preliminary data on the possible hypnogenic role of adenosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/7532163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF00874436

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

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