(Q40401407)

English

Extension of helix II of an HIV-1-directed hammerhead ribozyme with long antisense flanks does not alter kinetic parametersin vitrobut causes loss of the inhibitory potential in living cells

scientific article published on September 25, 1994

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Extension of helix II of an HIV-1-directed hammerhead ribozyme with long antisense flanks does not alter kinetic parameters in vitro but causes loss of the inhibitory potential in living cells (English)

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Extension of helix II of an HIV-1-directed hammerhead ribozyme with long antisense flanks does not alter kinetic parametersin vitrobut causes loss of the inhibitory potential in living cells (English)

1 reference

10.1093/NAR/22.19.3951

https://api.crossref.org/works/10.1093/NAR/22.19.3951

17 May 2024

0 references

nucleic acid tertiary structure

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7524030

17 May 2024

author name string

M. Homann

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7524030

17 May 2024

M. Tabler

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7524030

17 May 2024

S. Tzortzakaki

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7524030

17 May 2024

G. Sczakiel

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7524030

17 May 2024

language of work or name

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7524030

17 May 2024

publication date

1 September 1994

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

25 September 1994

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7524030

17 May 2024

full work available at URL

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC308395

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7524030

17 May 2024

https://europepmc.org/articles/PMC308395

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7524030

17 May 2024

https://europepmc.org/articles/PMC308395?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7524030

17 May 2024

http://academic.oup.com/nar/article-pdf/22/19/3951/7121891/22-19-3951.pdf

Portable Document Format

1 reference

10.1093/NAR/22.19.3951

https://api.crossref.org/works/10.1093/NAR/22.19.3951

17 May 2024

Nucleic Acids Research

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

22

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

19

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

3951-3957

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

Satellite tobacco ringspot virus RNA: A subset of the RNA sequence is sufficient for autolytic processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

In vitro selection of fast-hybridizing and effective antisense RNAs directed against the human immunodeficiency virus type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

Cleavage of full-length beta APP mRNA by hammerhead ribozymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

Hammerhead ribozymes: importance of stem-loop II for activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

Incorporation of the catalytic domain of a hammerhead ribozyme into antisense RNA enhances its inhibitory effect on the replication of human immunodeficiency virus type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

Inhibition of HIV-1 replication by ribozymes that show poor activity in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

A kinetic and thermodynamic framework for the hammerhead ribozyme reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

Selective cleavage of bcr-abl chimeric RNAs by a ribozyme targeted to non-contiguous sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

Protein enhancement of hammerhead ribozyme catalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

Can hammerhead ribozymes be efficient tools to inactivate gene function?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

RNA annealing activities in HeLa nuclei.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

Activity of hammerhead ribozymes containing non-nucleotidic linkers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

Optimal computer folding of large RNA sequences using thermodynamics and auxiliary information

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

Self-cleavage of virusoid RNA is performed by the proposed 55-nucleotide active site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

A catalytic 13-mer ribozyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

Self-cleavage of plus and minus RNAs of a virusoid and a structural model for the active sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

Renaturation of complementary DNA strands mediated by purified mammalian heterogeneous nuclear ribonucleoprotein A1 protein: implications for a mechanism for rapid molecular assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

Identification and analysis of antisense RNA target regions of the human immunodeficiency virus type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

Rapid renaturation of complementary DNA strands mediated by cationic detergents: a role for high-probability binding domains in enhancing the kinetics of molecular assembly processes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

Substrate sequence effects on "hammerhead" RNA catalytic efficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

Numbering system for the hammerhead

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

Chimeric DNA-RNA hammerhead ribozymes have enhanced in vitro catalytic efficiency and increased stability in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

Heterogeneous nuclear ribonucleoprotein A1 catalyzes RNA.RNA annealing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

22 September 2017

Ribozyme mediated destruction of RNA in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

25 September 2017

Control of replication of plasmid R1: kinetics of in vitro interaction between the antisense RNA, CopA, and its target, CopT.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

25 September 2017

Hammerhead ribozyme-mediated cleavage of the long terminal repeat RNA of human immunodeficiency virus type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

15 June 2018

Catalytic antisense RNAs produced by incorporating ribozyme cassettes into cDNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

15 June 2018

Cytoplasmic delivery of ribozymes leads to efficient reduction in alpha-lactalbumin mRNA levels in C127I mouse cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

15 June 2018

Expression of a chimeric ribozyme gene results in endonucleolytic cleavage of target mRNA and a concomitant reduction of gene expression in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

15 June 2018

Complementary large loops determine the rate of RNA duplex formation in vitro in the case of an effective antisense RNA directed against the human immunodeficiency virus type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

20 August 2018

Attenuation of white gene expression in transgenic Drosophila melanogaster: possible role of a catalytic antisense RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

20 August 2018

Simple RNA enzymes with new and highly specific endoribonuclease activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308395

20 August 2018

Cleavage of specific sites of RNA by designed ribozymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/7524030

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of cole 1 plasmid replication: Enhancement of binding of RNA I to the primer transcript by the rom protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/7524030

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A small catalytic oligoribonucleotide

1 reference

https://pubmed.ncbi.nlm.nih.gov/7524030

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/NAR/22.19.3951

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 September 2017

ResearchGate publication ID

0 references

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