(Q40415955)

English

CD437, a synthetic retinoid, induces apoptosis in human respiratory epithelial cells via caspase-independent mitochondrial and caspase-8-dependent pathways both up-regulated by JNK signaling pathway

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Europe PubMed Central

PubMed publication ID

20 September 2017

CD437, a synthetic retinoid, induces apoptosis in human respiratory epithelial cells via caspase-independent mitochondrial and caspase-8-dependent pathways both up-regulated by JNK signaling pathway (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

author name string

Emmanuelle Boisvieux-Ulrich

1

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Matthieu Sourdeval

2

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Europe PubMed Central

PubMed publication ID

20 September 2017

Francelyne Marano

3

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Europe PubMed Central

PubMed publication ID

20 September 2017

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publication date

18 April 2005

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Europe PubMed Central

PubMed publication ID

20 September 2017

Experimental Cell Research

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Europe PubMed Central

PubMed publication ID

20 September 2017

307

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Europe PubMed Central

PubMed publication ID

20 September 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

76-90

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Identification of synthetic retinoids with selectivity for human nuclear retinoic acid receptor gamma

1 reference

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Differential effects of several retinoid receptor-selective ligands on squamous differentiation and apoptosis in airway epithelial cells

1 reference

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Effects of retinoic acid receptor-selective agonists on human nasal epithelial cell differentiation

1 reference

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Effects of Various Synthetic Retinoids on Proliferation and Immunophenotype of Human Melanoma Cells In Vitro

1 reference

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Treatment of melanoma cells with the synthetic retinoid CD437 induces apoptosis via activation of AP-1 in vitro, and causes growth inhibition in xenografts in vivo

1 reference

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Growth-inhibitory effects of the synthetic retinoid CD437 against ovarian carcinoma models in vitro and in vivo

1 reference

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Induction of apoptosis in human non-small cell lung carcinoma cells by the novel synthetic retinoid CD437

1 reference

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In acute promyelocytic leukemia NB4 cells, the synthetic retinoid CD437 induces contemporaneously apoptosis, a caspase-3-mediated degradation of PML/RARalpha protein and the PML retargeting on PML-nuclear bodies

1 reference

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Elucidation of molecular events mediating induction of apoptosis by synthetic retinoids using a CD437-resistant ovarian carcinoma cell line

1 reference

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Molecular determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer cell lines.

1 reference

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Bcl-X(L) expression and its downregulation by a novel retinoid in breast carcinoma cells

1 reference

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Rapid induction of apoptosis in human C33A cervical carcinoma cells by the synthetic retinoid 6-[3-(1-adamantyl)hydroxyphenyl]-2-naphtalene carboxylic acid (CD437)

1 reference

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Inhibition of cell proliferation and induction of apoptosis by the retinoid AHPN in human lung carcinoma cells.

1 reference

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7 January 2021

Induction of apoptosis in ovarian carcinoma cells by AHPN/CD437 is mediated by retinoic acid receptors

1 reference

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7 January 2021

Implication of multiple mechanisms in apoptosis induced by the synthetic retinoid CD437 in human prostate carcinoma cells

1 reference

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The RARgamma selective agonist CD437 inhibits gastric cell growth through the mechanism of apoptosis.

1 reference

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Induction of apoptosis of human B-CLL and ALL cells by a novel retinoid and its nonretinoidal analog

1 reference

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The apoptotic action of the retinoid CD437/AHPN: diverse effects, common basis

1 reference

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7 January 2021

Specific activation of retinoic acid receptors (RARs) and retinoid X receptors reveals a unique role for RARgamma in induction of differentiation and apoptosis of S91 melanoma cells

1 reference

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7 January 2021

Retinoic acid receptor-independent mechanism of apoptosis of melanoma cells by the retinoid CD437 (AHPN).

1 reference

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7 January 2021

Identification of a unique binding protein specific for a novel retinoid inducing cellular apoptosis

1 reference

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7 January 2021

Induction of Egr-1 expression by the retinoid AHPN in human lung carcinoma cells is dependent on activated ERK1/2.

1 reference

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7 January 2021

Retinoids induce Fas(CD95) ligand cell surface expression via RARgamma and nur77 in T cells

1 reference

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7 January 2021

Synthetic retinoid CD437 promotes rapid apoptosis in malignant human epidermal keratinocytes and G1 arrest in their normal counterparts

1 reference

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Proliferation-dependent induction of apoptosis by the retinoid CD437 in p53-mutated keratinocytes

1 reference

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7 January 2021

Mechanisms of apoptosis induced by the synthetic retinoid CD437 in human non-small cell lung carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.02.005

7 January 2021

Activation of the p38 and JNK/SAPK mitogen-activated protein kinase pathways during apoptosis is mediated by a novel retinoid

1 reference

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7 January 2021

Involvement of cyclin-dependent kinase activities in CD437-induced apoptosis

1 reference

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Effects of a novel synthetic retinoid on malignant glioma in vitro: inhibition of cell proliferation, induction of apoptosis and differentiation.

1 reference

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Synthetic retinoid CD437 induces S-phase arrest and apoptosis in human prostate cancer cells LNCaP and PC-3

1 reference

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Identification and characterization of a cell cycle and apoptosis regulatory protein-1 as a novel mediator of apoptosis signaling by retinoid CD437

1 reference

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7 January 2021

Pro-caspase-8 is predominantly localized in mitochondria and released into cytoplasm upon apoptotic stimulation

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.02.005

7 January 2021

Active caspase-8 translocates into the nucleus of apoptotic cells to inactivate poly(ADP-ribose) polymerase-2

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.02.005

7 January 2021

Cleavage of the nuclear matrix protein NuMA during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.02.005

7 January 2021

Review: nuclear lamins--structural proteins with fundamental functions

1 reference

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7 January 2021

Chromatin condensation during apoptosis is accompanied by degradation of lamin A+B, without enhanced activation of cdc2 kinase

1 reference

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NuMA and nuclear lamins behave differently in Fas-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.02.005

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Lamin-binding fragment of LAP2 inhibits increase in nuclear volume during the cell cycle and progression into S phase

1 reference

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HA95 and LAP2 beta mediate a novel chromatin-nuclear envelope interaction implicated in initiation of DNA replication

1 reference

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Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis

1 reference

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Apoptosis-inducing factor (AIF): a novel caspase-independent death effector released from mitochondria

1 reference

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Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death

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Overexpression of Helicard, a CARD-containing helicase cleaved during apoptosis, accelerates DNA degradation

1 reference

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Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death

1 reference

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Mitochondria and apoptosis

1 reference

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Adenine nucleotide translocator mediates the mitochondrial membrane permeabilization induced by lonidamine, arsenite and CD437.

1 reference

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Structure-function comparisons of the proapoptotic protein Bax in yeast and mammalian cells

1 reference

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Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

1 reference

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Movement of Bax from the cytosol to mitochondria during apoptosis

1 reference

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Membrane perturbations induced by the apoptotic Bax protein

1 reference

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7 January 2021

Regulated targeting of BAX to mitochondria.

1 reference

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Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2.

1 reference

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7 January 2021

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

1 reference

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Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

1 reference

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Role of Bcl-2 family members in caspase-independent apoptosis during Chlamydia infection.

1 reference

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JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis

1 reference

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Retinoid targets for apoptosis induction

1 reference

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Induction of apoptosis by retinoids and retinoic acid receptor gamma-selective compounds in mouse thymocytes through a novel apoptosis pathway

1 reference

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10.1016/J.YEXCR.2005.02.005

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

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