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Mammalian p53 can function as a transcription factor in yeast.
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scholarly article
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Europe PubMed Central
PMCID
312235
retrieved
20 September 2017
title
Mammalian p53 can function as a transcription factor in yeast.
(English)
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stated in
Europe PubMed Central
PMCID
312235
retrieved
20 September 2017
author name string
Schärer E
series ordinal
1
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stated in
Europe PubMed Central
PMCID
312235
retrieved
20 September 2017
Iggo R
series ordinal
2
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stated in
Europe PubMed Central
PMCID
312235
retrieved
20 September 2017
publication date
1 April 1992
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Europe PubMed Central
PMCID
312235
retrieved
20 September 2017
published in
Nucleic Acids Research
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stated in
Europe PubMed Central
PMCID
312235
retrieved
20 September 2017
volume
20
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stated in
Europe PubMed Central
PMCID
312235
retrieved
20 September 2017
page(s)
1539-1545
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stated in
Europe PubMed Central
PMCID
312235
retrieved
20 September 2017
issue
7
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stated in
Europe PubMed Central
PMCID
312235
retrieved
20 September 2017
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Monoclonal antibodies against simian virus 40 nuclear large T tumour antigen: epitope mapping, papova virus cross-reaction and cell surface staining
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22 September 2017
Molecular cloning and in vitro expression of a cDNA clone for human cellular tumor antigen p53.
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22 September 2017
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22 September 2017
Roles of two DNA-binding factors in replication, segregation and transcriptional repression mediated by a yeast silencer.
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22 September 2017
UASs and enhancers: common mechanism of transcriptional activation in yeast and mammals.
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22 September 2017
Clonal analysis of human colorectal tumors
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Mouse p53 blocks SV40 DNA replication in vitro and downregulates T antigen DNA helicase activity.
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Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life
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Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation.
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22 September 2017
Human ribosomal DNA: novel sequence organization in a 4.5-kb region upstream from the promoter.
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22 September 2017
Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents
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22 September 2017
The p53 proto-oncogene can act as a suppressor of transformation.
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22 September 2017
Recombination mediates production of an extrachromosomal circular DNA containing a transposon-like human element, THE-1
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22 September 2017
A growth factor-repressible gene associated with protein kinase C-mediated inhibition of adipocyte differentiation
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22 September 2017
Monoclonal antibody analysis of p53 expression in normal and transformed cells.
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PubMed Central
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22 September 2017
p53 functions as a cell cycle control protein in osteosarcomas
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PubMed Central
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22 September 2017
Wild-type, but not mutant, human p53 proteins inhibit the replication activities of simian virus 40 large tumor antigen.
1 reference
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PubMed Central
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22 September 2017
Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene
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PubMed Central
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22 September 2017
Suppression of human colorectal carcinoma cell growth by wild-type p53
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PubMed Central
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22 September 2017
Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.
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PubMed Central
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22 September 2017
p53: oncogene or anti-oncogene?
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PubMed Central
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22 September 2017
Identification of p53 as a sequence-specific DNA-binding protein
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PubMed Central
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22 September 2017
The p53 tumour suppressor gene.
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22 September 2017
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
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22 September 2017
Wild-type p53 can down-modulate the activity of various promoters.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
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22 September 2017
Analysis of p53 mutants for transcriptional activity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
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22 September 2017
Identification of the DNA binding site for NGFI-B by genetic selection in yeast.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
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22 September 2017
The nuclear protooncogenes c-jun and c-fos as regulators of DNA replication.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
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22 September 2017
p53 mutations in colorectal cancer
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
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22 September 2017
Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
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22 September 2017
The MCK enhancer contains a p53 responsive element.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
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22 September 2017
Analysis of p53 expression in human tumours: an antibody raised against human p53 expressed in Escherichia coli.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
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22 September 2017
A yeast chromosomal origin of DNA replication defined by multiple functional elements
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
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22 September 2017
A potential transcriptional activation element in the p53 protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
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25 September 2017
Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
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25 September 2017
Growth regulation of a cellular tumour antigen, p53, in nontransformed cells.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
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15 June 2018
Reconstitution of p53 expression in a nonproducer Ab-MuLV-transformed cell line by transfection of a functional p53 gene.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
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15 June 2018
Transcription factor OTF-1 is functionally identical to the DNA replication factor NF-III.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
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15 June 2018
A new anti-p53 monoclonal antibody, previously reported to be directed against the large T antigen of simian virus 40.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
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15 June 2018
p53 and DNA polymerase alpha compete for binding to SV40 T antigen.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
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15 June 2018
A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
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15 June 2018
DNA binding properties of murine p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
retrieved
15 June 2018
Mouse p53 inhibits SV40 origin-dependent DNA replication.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
retrieved
15 June 2018
The murine p53 protein blocks replication of SV40 DNA in vitro by inhibiting the initiation functions of SV40 large T antigen.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
retrieved
15 June 2018
Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: a comparison of the "hot spot" mutant phenotypes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
retrieved
15 June 2018
Temperature-dependent switching between "wild-type" and "mutant" forms of p53-Val135.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
retrieved
15 June 2018
Association of human papillomavirus types 16 and 18 E6 proteins with p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
retrieved
15 June 2018
Presence of a potent transcription activating sequence in the p53 protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
retrieved
15 June 2018
Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
retrieved
15 June 2018
Protein synthesis required to anchor a mutant p53 protein which is temperature-sensitive for nuclear transport.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
retrieved
15 June 2018
Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
retrieved
15 June 2018
p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
retrieved
15 June 2018
Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
retrieved
15 June 2018
Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
retrieved
15 June 2018
SV40 large T shares an antigenic determinant with a cellular protein of molecular weight 68,000.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
retrieved
20 August 2018
A yeast silencer contains sequences that can promote autonomous plasmid replication and transcriptional activation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=312235
retrieved
20 August 2018
Identifiers
DOI
10.1093/NAR/20.7.1539
1 reference
stated in
Europe PubMed Central
PMCID
312235
retrieved
20 September 2017
PMCID
312235
1 reference
stated in
Europe PubMed Central
PMCID
312235
retrieved
20 September 2017
PubMed ID
1579447
1 reference
stated in
Europe PubMed Central
PMCID
312235
retrieved
20 September 2017
ResearchGate publication ID
21577177
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