(Q40425461)

20 September 2017

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title

P-glycoprotein expression and regulation. Age-related changes and potential effects on drug therapy (English)

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20 September 2017

S Gupta

1

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20 September 2017

publication date

1 July 1995

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20 September 2017

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20 September 2017

volume

7

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20 September 2017

issue

1

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20 September 2017

page(s)

19-29

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https://scigraph.springernature.com/pub.10.2165/00002512-199507010-00003

20 September 2017

exact match

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cites work

Structure and expression of the human MDR (P-glycoprotein) gene family

1 reference

12 December 2020

Study of membrane orientation and glycosylated extracellular loops of mouse P-glycoprotein by in vitro translation

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12 December 2020

The multidrug resistance (mdr1) gene product functions as an ATP channel

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12 December 2020

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12 December 2020

Flow cytometric analysis of P-glycoprotein in normal and leukemic cells

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12 December 2020

Resistance of multidrug-resistant lines to natural killer-like cell-mediated cytotoxicity

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12 December 2020

Modulation of drug permeability in chinese hamster ovary cells. Possible role for phosphorylation of surface glycoproteins

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12 December 2020

Susceptibility of multidrug-resistant human leukemia cell lines to human interleukin 2-activated killer cells

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12 December 2020

Peptide transport by the multidrug resistance pump

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12 December 2020

Characterization of the azidopine and vinblastine binding site of P-glycoprotein

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12 December 2020

Resistance to natural killer cell-mediated cytolysis by a pleiotropic drug-resistant human erythroleukemia (K562-R) cell line.

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12 December 2020

The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin

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12 December 2020

Localization of multidrug resistance-associated DNA sequences to human chromosome 7.

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12 December 2020

Identification of the multidrug resistance-related P-glycoprotein as a cyclosporine binding protein

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12 December 2020

Human immunodeficiency virus I-induced expression of P-glycoprotein

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12 December 2020

Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein

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12 December 2020

Modulation of activity of the promoter of the human MDR1 gene by Ras and p53.

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12 December 2020

The role of the MDR1 (P-glycoprotein) gene in multidrug resistance in vitro and in vivo

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12 December 2020

Localization of the human multiple drug resistance gene, MDR1, to 7q21.1

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12 December 2020

Mdr1/P-glycoprotein expression in natural killer (NK) cells enriched from peripheral or umbilical cord blood

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12 December 2020

Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells

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12 December 2020

P-glycoprotein expression and function in circulating blood cells from normal volunteers.

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12 December 2020

The CF Gene Product as a Member of a Membrane Transporter (TM6-NBF) Super Family

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12 December 2020

Role of oncogenes in the regulation of MHC antigen expression

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12 December 2020

Multidrug resistant gene 1 product in human T cell subsets: role of protein kinase C isoforms and regulation by cyclosporin A

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12 December 2020

Preferential expression and activity of multidrug resistance gene 1 product (P-glycoprotein), a functionally active efflux pump, in human CD8+ T cells: a role in cytotoxic effector function

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12 December 2020

P-glycoprotein (MDR 1 gene product) in cells of the immune system: its possible physiologic role and alteration in aging and human immunodeficiency virus-1 (HIV-1) infection

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12 December 2020

Tissue distribution of P-glycoprotein encoded by a multidrug-resistant gene as revealed by a monoclonal antibody, MRK 16

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12 December 2020

Diverse multidrug-resistance-modification agents inhibit cytolytic activity of natural killer cells

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12 December 2020

Biochemistry of multidrug resistance mediated by the multidrug transporter

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12 December 2020

Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum

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12 December 2020

Human P-glycoprotein transports cyclosporin A and FK506.

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12 December 2020

Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum.

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12 December 2020

Topology of P-glycoprotein as determined by epitope mapping of MRK-16 monoclonal antibody.

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12 December 2020

Resistance of HIV-1 to AZT might also involve the cellular expression of multidrug resistance P-glycoprotein

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12 December 2020

Regulation by phorbol ester and protein kinase C inhibitors, and by a protein phosphatase inhibitor (okadaic acid), of P-glycoprotein phosphorylation and relationship to drug accumulation in multidrug-resistant human KB cells

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12 December 2020

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

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12 December 2020

Phosphorylation of the Mr 170,000 to 180,000 glycoprotein specific to multidrug-resistant tumor cells: effects of verapamil, trifluoperazine, and phorbol esters.

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12 December 2020

Increased function of P-glycoprotein in T lymphocyte subsets of aging mice.

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12 December 2020

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

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12 December 2020

Progesterone interacts with P-glycoprotein in multidrug-resistant cells and in the endometrium of gravid uterus

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12 December 2020

Glycosylation of P-glycoprotein in a multidrug-resistant KB cell line, and in the human tissues

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12 December 2020

Membrane signal transduction in T cells in aging humans

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12 December 2020

Two different regions of P-glycoprotein [corrected] are photoaffinity-labeled by azidopine.

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12 December 2020

Multidrug resistance activity in human lymphocytes

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12 December 2020

Multidrug-resistance phenotype of a subpopulation of T-lymphocytes without drug selection

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12 December 2020

Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.

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12 December 2020

Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins

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12 December 2020

Kinetics of cellular oncogene expression in mouse lymphocytes. I. Expression of c-myc and c-ras-Ha in T lymphocytes induced by various mitogens

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12 December 2020

Expression of the mdr-1/P-170 gene in patients with acute lymphoblastic leukemia.

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12 December 2020

Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes

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12 December 2020

Characterization of multidrug resistance by fluorescent dyes.

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12 December 2020

Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins

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12 December 2020

P-glycoprotein: multidrug-resistance and a superfamily of membrane-associated transport proteins.

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12 December 2020

Apparent stronger expression in the human adrenal cortex than in the human adrenal medulla of Mr 170,000-180,000 P-glycoprotein

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12 December 2020

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12 December 2020

Biology of natural killer cells

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12 December 2020

Isolation and sequence of the promoter region of the human multidrug-resistance (P-glycoprotein) gene.

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12 December 2020

Beta 1 integrin (CD29) expression on human postnatal T cell subsets defined by selective CD45 isoform expression

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12 December 2020

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

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12 December 2020

Expression of a multidrug-resistance gene in human tumors and tissues

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12 December 2020

Transport protein genes in the murine MHC: possible implications for antigen processing

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12 December 2020

ATP-dependent transport systems in bacteria and humans: relevance to cystic fibrosis and multidrug resistance

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12 December 2020

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

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12 December 2020

Subpopulations of normal peripheral blood and bone marrow cells express a functional multidrug resistant phenotype

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12 December 2020

The human multidrug resistance gene: sequences upstream and downstream of the initiation site influence transcription

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12 December 2020

P-glycoprotein expression in normal and reactive bone marrows

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12 December 2020

Phosphorylation of the multidrug resistance associated glycoprotein.

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12 December 2020

Multidrug Resistance: A Novel Class of Membrane-Associated Transport Proteins is Identified

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12 December 2020

Expression of multidrug resistance gene mdr1 mRNA in a subset of normal bone marrow cells

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12 December 2020

Structural and functional analyses of the promoter of the murine multidrug resistance gene mdr3/mdr1a reveal a negative element containing the AP-1 binding site

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12 December 2020

Cyclic AMP-dependent protein kinase regulates sensitivity of cells to multiple drugs

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12 December 2020

Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport

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12 December 2020

Expression of multidrug resistance gene (MDR-1) in human normal leukocytes.

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12 December 2020

Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone

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12 December 2020

Stability and covalent modification of P-glycoprotein in multidrug-resistant KB cells

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12 December 2020

Expression, methylation and chromatin structure of the p53 gene in untransformed and human T-cell leukemia virus type I-transformed human T-lymphocytes

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12 December 2020

Mammalian multidrug-resistance gene: correlation of exon organization with structural domains and duplication of an ancestral gene

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12 December 2020

10.2165/00002512-199507010-00003

Identifiers

DOI

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Dimensions Publication ID

20 September 2017

1043555386

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