(Q40429889)

20 September 2017

1 reference

title

Mitochondrial toxicity of antiviral drugs (English)

1 reference

20 September 2017

0 references

Lewis W

1

1 reference

PubMed ID

7585087

20 September 2017

Dalakas MC

series ordinal

2

1 reference

PubMed ID

7585087

20 September 2017

language of work or name

English

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publication date

1 May 1995

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20 September 2017

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20 September 2017

1

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20 September 2017

417-422

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20 September 2017

5

1 reference

https://scigraph.springernature.com/pub.10.1038/nm0595-417

20 September 2017

0 references

cites work

Empirical and rational approaches for development of inhibitors of the human immunodeficiency virus--HIV-1.

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

Mitochondrial myopathy caused by long-term zidovudine therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

Dideoxyinosine in Children with Symptomatic Human Immunodeficiency Virus Infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

Dilated cardiomyopathy in a zidovudine-treated AIDS patient

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

Eukaryotic DNA polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

Deoxyribonucleotide analogs as inhibitors and substrates of DNA polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

Clinical pharmacology of 3'-azido-2',3'-dideoxythymidine (zidovudine) and related dideoxynucleosides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

Depletion of muscle mitochondrial DNA in AIDS patients with zidovudine-induced myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

Ultrastructural characteristics and DNA immunocytochemistry in human immunodeficiency virus and zidovudine-associated myopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

Cardiomyopathy Associated with Antiretroviral Therapy in Patients with HIV Infection: A Report of Six Cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

Cardiac structure and function in children with human immunodeficiency virus infection treated with zidovudine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

Lactic acidosis complicating the acquired immunodeficiency syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

The pc12 cell as a model for studies of the mechanism of induction of peripheral neuropathy by anti-HIV-1 dideoxynucleoside analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

US health agencies at odds over trial deaths

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

The development of mitochondrial medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Mitochondrial genetics: a paradigm for aging and degenerative diseases?

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Acyclovir: discovery, mechanism of action, and selectivity

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Overview of the preclinical development of an antiretroviral drug, 2',3'-dideoxyinosine

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Molecular targets for AIDS therapy

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Cardiac mitochondrial DNA polymerase-gamma is inhibited competitively and noncompetitively by phosphorylated zidovudine

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Cellular and molecular events leading to mitochondrial toxicity of 1-(2-deoxy-2-fluoro-1-beta-D-arabinofuranosyl)-5-iodouracil in human liver cells

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Deaths in US fialuridine trial

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Hepatitis study. Drug trial deaths deemed unavoidable

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Overview of phase I trials of 2',3'-dideoxyinosine (ddI) conducted on adult patients

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Hepatomegaly with severe steatosis in HIV-seropositive patients

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Interactions between deoxyribonucleotide and DNA synthesis

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Diseases of the mitochondrial DNA.

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Mitochondrial DNA sequence variation in human evolution and disease.

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

3'-Azido-3'-deoxythymidine (AZT) inhibits proliferation in vitro of human haematopoietic progenitor cells

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Reversal of azidothymidine-induced bone marrow suppression by 2',3'-dideoxythymidine as studied by hemopoietic clonal culture

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Pearson's marrow-pancreas syndrome. A multisystem mitochondrial disorder in infancy

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Zidovudine induces molecular, biochemical, and ultrastructural changes in rat skeletal muscle mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Partial cytochrome c oxidase deficiency and cytoplasmic bodies in patients with zidovudine myopathy

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Determination of the blood lactate:pyruvate ratio as a noninvasive test for the diagnosis of zidovudine myopathy.

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

31P magnetic resonance spectroscopy suggests impaired mitochondrial function in AZT-treated HIV-infected patients

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Zidovudine-induced mitochondrial myopathy is associated with muscle carnitine deficiency and lipid storage

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Zidovudine myopathy: a distinctive disorder associated with mitochondrial dysfunction

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Reye's syndrome in adult with AIDS

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Reversible axonal neuropathy from the treatment of AIDS and related disorders with 2',3'-dideoxycytidine (ddC).

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Effects of 2'-fluorinated arabinosyl-pyrimidine nucleosides on duck hepatitis B virus DNA level in serum and liver of chronically infected ducks

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Mammalian DNA polymerases alpha, beta, gamma, delta, and epsilon incorporate fialuridine (FIAU) monophosphate into DNA and are inhibited competitively by FIAU Triphosphate

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Fialuridine accumulates in DNA of dogs, monkeys, and rats following long-term oral administration

1 reference

https://api.crossref.org/works/10.1038%2FNM0595-417

7 January 2021

Identifiers

DOI

10.1038/NM0595-417

1 reference

20 September 2017

1 reference

PubMed ID

7585087