(Q40430999)

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Electrophilic PPARγ ligands inhibit corneal fibroblast to myofibroblast differentiation in vitro: a potentially novel therapy for corneal scarring

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scholarly article

1 reference

Europe PubMed Central

20 September 2017

Electrophilic PPARγ ligands inhibit corneal fibroblast to myofibroblast differentiation in vitro: a potentially novel therapy for corneal scarring (English)

1 reference

Europe PubMed Central

20 September 2017

author name string

A E Kuriyan

1

1 reference

Europe PubMed Central

20 September 2017

G M Lehmann

2

1 reference

Europe PubMed Central

20 September 2017

A A Kulkarni

3

1 reference

Europe PubMed Central

20 September 2017

C F Woeller

4

1 reference

Europe PubMed Central

20 September 2017

S E Feldon

5

1 reference

Europe PubMed Central

20 September 2017

H B Hindman

6

1 reference

Europe PubMed Central

20 September 2017

P J Sime

7

1 reference

Europe PubMed Central

20 September 2017

K R Huxlin

8

1 reference

Europe PubMed Central

20 September 2017

R P Phipps

9

1 reference

Europe PubMed Central

20 September 2017

publication date

8 December 2011

1 reference

Europe PubMed Central

20 September 2017

Experimental Eye Research

1 reference

Europe PubMed Central

20 September 2017

94

1 reference

Europe PubMed Central

20 September 2017

1

1 reference

Europe PubMed Central

20 September 2017

136-145

1 reference

Europe PubMed Central

20 September 2017

Peroxisome proliferator-activated receptor gamma ligands inhibit transforming growth factor-beta-induced, hyaluronan-dependent, T cell adhesion to orbital fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

The aryl hydrocarbon receptor ligand ITE inhibits TGFβ1-induced human myofibroblast differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

PPAR-γ ligands repress TGFβ-induced myofibroblast differentiation by targeting the PI3K/Akt pathway: implications for therapy of fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

Pioglitazone inhibits TGFβ induced keratocyte transformation to myofibroblast and extracellular matrix production.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

Corneal myofibroblast generation from bone marrow-derived cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

Antifibrotic effect by activation of peroxisome proliferator-activated receptor-gamma in corneal fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

Expression of PDGF receptor-alpha in corneal myofibroblasts in situ.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

Electrophilic peroxisome proliferator-activated receptor-gamma ligands have potent antifibrotic effects in human lung fibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

Corneal stroma PDGF blockade and myofibroblast development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

Optical effects of anti-TGFbeta treatment after photorefractive keratectomy in a cat model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

Corneal crystallins and the development of cellular transparency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer.

1 reference

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22 September 2017

Activated human T lymphocytes express cyclooxygenase-2 and produce proadipogenic prostaglandins that drive human orbital fibroblast differentiation to adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

PPARs and other nuclear receptors in inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

The keratocyte: corneal stromal cell with variable repair phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

Stromal haze, myofibroblasts, and surface irregularity after PRK

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

How the cornea heals: cornea-specific repair mechanisms affecting surgical outcomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

2-Cyano-3,12-dioxoolean-1,9-dien-28-oic acid and related compounds inhibit growth of colon cancer cells through peroxisome proliferator-activated receptor gamma-dependent and -independent pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

Reversible Michael addition of thiols as a new tool for dynamic combinatorial chemistry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

Peroxisome proliferator-activated receptor-gamma-independent repression of collagenase gene expression by 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid and prostaglandin 15-deoxy-delta(12,14) J2: a role for Smad signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

Peroxisome proliferator-activated receptors: a critical review on endogenous pathways for ligand generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

A dominant negative PPARgamma mutant shows altered cofactor recruitment and inhibits adipogenesis in 3T3-L1 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

Indications and outcome of optical partial thickness lamellar keratoplasty

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

In vivo confocal microscopy of the human cornea.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

Proteoglycan expression during transforming growth factor beta -induced keratocyte-myofibroblast transdifferentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

The wound healing response after laser in situ keratomileusis and photorefractive keratectomy: elusive control of biological variability and effect on custom laser vision correction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

Corneal blindness: a global perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

A synthetic triterpenoid, 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO), is a ligand for the peroxisome proliferator-activated receptor gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

Keratocyte and fibroblast phenotypes in the repairing cornea

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

The cellular basis of corneal transparency: evidence for 'corneal crystallins'.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

Neutralizing antibody to TGFbeta modulates stromal fibrosis but not regression of photoablative effect following PRK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

Novel aspects of the ultrastructural organization of human corneal keratocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

Temporal relationships of F-actin bundle formation, collagen and fibronectin matrix assembly, and fibronectin receptor expression to wound contraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

22 September 2017

The triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid and its derivatives elicit human lymphoid cell apoptosis through a novel pathway involving the unregulated mitochondrial permeability transition pore

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

15 June 2018

A mouse model for the study of recurrent corneal epithelial erosions: alpha9beta1 integrin implicated in progression of the disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

15 June 2018

A novel synthetic oleanane triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

15 June 2018

PPAR-gamma agonist attenuates renal interstitial fibrosis and inflammation through reduction of TGF-beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

20 August 2018

Endothelin is a downstream mediator of profibrotic responses to transforming growth factor beta in human lung fibroblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

20 August 2018

PPARgamma agonists inhibit TGF-beta induced pulmonary myofibroblast differentiation and collagen production: implications for therapy of lung fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

20 August 2018

TGFbeta induced myofibroblast differentiation of rabbit keratocytes requires synergistic TGFbeta, PDGF and integrin signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

20 August 2018

Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

20 August 2018

Thymosin beta 4 promotes corneal wound healing and decreases inflammation in vivo following alkali injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

20 August 2018

Orbital fibroblast heterogeneity may determine the clinical presentation of thyroid-associated ophthalmopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3259184

20 August 2018

Effect of overexpression of PPARgamma on the healing process of corneal alkali burn in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22178289

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor gamma inhibits transforming growth factor beta-induced connective tissue growth factor expression in human aortic smooth muscle cells by interfering with Smad3

1 reference

https://pubmed.ncbi.nlm.nih.gov/22178289

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EGF, EGF receptor, basic FGF, TGF beta-1, and IL-1 alpha mRNA in human corneal epithelial cells and stromal fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/22178289

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of fibroblast-mediated collagen gel contraction by platelet-derived growth factor, interleukin-1 alpha and transforming growth factor-beta 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/22178289

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of alpha-smooth muscle (alpha-SM) actin during corneal stromal wound healing

1 reference

https://pubmed.ncbi.nlm.nih.gov/22178289

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of fibroblast proliferation in three-dimensional collagen gel matrix

1 reference

https://pubmed.ncbi.nlm.nih.gov/22178289

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of alpha-smooth muscle actin expression and myofibroblast transformation in cultured corneal keratocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22178289

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of corneal fibrosis by topical application of blocking antibodies to TGF beta in the rabbit

1 reference

https://pubmed.ncbi.nlm.nih.gov/22178289

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta 1 promotes contraction of collagen gel by bovine corneal fibroblasts through differentiation of myofibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/22178289

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human neutrophil elastase augments fibroblast-mediated contraction of released collagen gels

1 reference

https://pubmed.ncbi.nlm.nih.gov/22178289

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deep lamellar keratoplasty by intracorneal dissection: a prospective clinical and confocal microscopic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22178289

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The peroxisome proliferator-activated receptor gamma (PPARgamma) ligands 15-deoxy-Delta12,14-prostaglandin J2 and ciglitazone induce human B lymphocyte and B cell lymphoma apoptosis by PPARgamma-independent mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/22178289

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.EXER.2011.11.018

1 reference

Europe PubMed Central

20 September 2017

1 reference

Europe PubMed Central

20 September 2017

1 reference

Europe PubMed Central

20 September 2017

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