(Q40432274)

20 September 2017

1 reference

title

Thrombolytic agents in development (English)

1 reference

20 September 2017

Thrombolytic Agents in Development (English)

1 reference

10.2165/00003495-199550010-00003

Crossref

DOI

https://api.crossref.org/works/10.2165/00003495-199550010-00003

27 May 2024

1 reference

M. Verstraete

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7588087

27 May 2024

H. R. Lijnen

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7588087

27 May 2024

D. Collen

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A7588087

27 May 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7588087

27 May 2024

publication date

1 July 1995

1 reference

20 September 2017

1 reference

20 September 2017

volume

50

1 reference

20 September 2017

issue

1

1 reference

20 September 2017

page(s)

29-42

1 reference

https://scigraph.springernature.com/pub.10.2165/00003495-199550010-00003

20 September 2017

exact match

0 references

cites work

Comparative fibrinolytic properties of staphylokinase and streptokinase in animal models of venous thrombosis

1 reference

12 December 2020

Recombinant variants of tissue-type plasminogen activator containing amino acid substitutions in the finger domain

1 reference

12 December 2020

High resolution analysis of functional determinants on human tissue-type plasminogen activator

1 reference

12 December 2020

Mapping of the catalytic site of CHO‐t‐PA and the t‐PA variant BM 06.022 by synthetic inhibitors and substrates

1 reference

12 December 2020

Thrombolytic effects of recombinant fibrolase or APSAC in a canine model of carotid artery thrombosis

1 reference

12 December 2020

High yield production and purification of recombinant staphylokinase for thrombolytic therapy.

1 reference

12 December 2020

Functional properties of recombinant staphylokinase variants obtained by site-specific mutagenesis of methionine-26.

1 reference

12 December 2020

Thrombolytic properties of Desmodus rotundus (vampire bat) salivary plasminogen activator in experimental pulmonary embolism in rats.

1 reference

12 December 2020

Clearance of a novel recombinant tissue plasminogen activator in rabbits

1 reference

12 December 2020

Induction of sustained patency after clot-selective coronary thrombolysis with Hybrid-B, a genetically engineered plasminogen activator with a prolonged biological half-life

1 reference

12 December 2020

Thrombolytic activity of two chimeric recombinant plasminogen activators (FK2tu-PA and K2tu-PA) in rabbits

1 reference

12 December 2020

Purification and characterization of a novel low molecular weight form of single-chain urokinase-type plasminogen activator

1 reference

12 December 2020

On the immunogenicity of recombinant staphylokinase in patients and in animal models

1 reference

12 December 2020

Conjugation to an antifibrin monoclonal antibody enhances the fibrinolytic potency of tissue plasminogen activator in vitro

1 reference

12 December 2020

Biochemical and thrombolytic properties of a low molecular weight form (comprising Leu144 through Leu411) of recombinant single-chain urokinase-type plasminogen activator.

1 reference

12 December 2020

Deletion of a tripeptide sequence from the growth-factor domain of tissue-type plasminogen activator prolongs in vivo circulation

1 reference

12 December 2020

Enhancement of the thrombolytic potency of plasminogen activators by conjugation with clot-specific monoclonal antibodies

1 reference

12 December 2020

Vampire bat salivary plasminogen activator is quiescent in human plasma in the absence of fibrin unlike human tissue plasminogen activator

1 reference

12 December 2020

Isolation, characterization, and cDNA cloning of a vampire bat salivary plasminogen activator

1 reference

12 December 2020

Coronary thrombolysis with K1K2Pu, a chimeric tissue-type and urokinase-type plasminogen activator: a feasibility study in six patients with acute myocardial infarction

1 reference

12 December 2020

Thrombolytic and pharmacokinetic properties of a recombinant chimeric plasminogen activator consisting of a fibrin fragment D-dimer specific humanized monoclonal antibody and a truncated single-chain urokinase

1 reference

12 December 2020

A faster-acting and more potent form of tissue plasminogen activator

1 reference

12 December 2020

A direct-acting fibrinolytic enzyme from the venom of Agkistrodon contortrix contortrix: effects on various components of the human blood coagulation and fibrinolysis systems

1 reference

12 December 2020

Strategies for the improvement of thrombolytic agents

1 reference

12 December 2020

A recombinant, chimeric enzyme with a novel mechanism of action leading to greater potency and selectivity than tissue-type plasminogen activator

1 reference

12 December 2020

Purification and characterization of a fibrinolytic enzyme from venom of the southern copperhead snake (Agkistrodon contortrix contortrix).

1 reference

12 December 2020

A variant of t-PA (T103N, KHRR 296-299 AAAA) that, by bolus, has increased potency and decreased systemic activation of plasminogen

1 reference

12 December 2020

Platelets inhibit fibrinolysis in vitro by both plasminogen activator inhibitor-1-dependent and -independent mechanisms.

1 reference

12 December 2020

Biochemical properties of the kringle 2 and protease domains are maintained in the refolded t-PA deletion variant BM 06.022

1 reference

12 December 2020

Vampire bat salivary plasminogen activator promotes rapid and sustained reperfusion without concomitant systemic plasminogen activation in a canine model of arterial thrombosis

1 reference

12 December 2020

Fibrin affinity and clearance of t-PA deletion and substitution analogues

1 reference

12 December 2020

Protein engineering of novel plasminogen activators with increased thrombolytic potency in rabbits relative to activase

1 reference

12 December 2020

Thrombolytic and pharmacokinetic properties of chimeric tissue-type and urokinase-type plasminogen activators

1 reference

12 December 2020

Tyrosine 67 in the epidermal growth factor-like domain of tissue-type plasminogen activator is important for clearance by a specific hepatic receptor

1 reference

12 December 2020

Coronary thrombolysis with Desmodus salivary plasminogen activator in dogs. Fast and persistent recanalization by intravenous bolus administration

1 reference

12 December 2020

Comparative thrombolytic properties of tissue-type plasminogen activator and of a plasminogen activator inhibitor-1-resistant glycosylation variant, in a combined arterial and venous thrombosis model in the dog.

1 reference

12 December 2020

Thrombolysis by a fibrin-specific antibody Fab'-urokinase conjugate

1 reference

12 December 2020

Vampire bat salivary plasminogen activator exhibits a strict and fastidious requirement for polymeric fibrin as its cofactor, unlike human tissue-type plasminogen activator. A kinetic analysis

1 reference

12 December 2020

Mechanisms of activation of mammalian plasma fibrinolytic systems with streptokinase and with recombinant staphylokinase

1 reference

12 December 2020

Thrombolysis with an Escherichia coli-produced recombinant plasminogen activator (BM 06.022) in the rabbit model of jugular vein thrombosis.

1 reference

12 December 2020

Pharmacokinetic and distribution analysis of variant forms of tissue-type plasminogen activator with prolonged clearance in rat.

1 reference

12 December 2020

Thrombolytic activity of a novel plasminogen activator, LY210825, compared with recombinant tissue-type plasminogen activator in a canine model of coronary artery thrombosis

1 reference

12 December 2020

Characterization of a modified human tissue plasminogen activator comprising a kringle-2 and a protease domain

1 reference

12 December 2020

Resolution of isoforms of natural and recombinant fibrolase, the fibrinolytic enzyme from Agkistrodon contortrix contortrix snake venom, and comparison of their EDTA sensitivities

1 reference

12 December 2020

Dose-ranging study of the novel recombinant plasminogen activator BM 06.022 in healthy volunteers.

1 reference

12 December 2020

The plasminogen activator family from the salivary gland of the vampire bat Desmodus rotundus: cloning and expression

1 reference

12 December 2020

Serpin-resistant mutants of human tissue-type plasminogen activator

1 reference

12 December 2020

Coronary thrombolysis with recombinant staphylokinase in patients with evolving myocardial infarction

1 reference

12 December 2020

Comparative immunogenicity and thrombolytic properties toward arterial and venous thrombi of streptokinase and recombinant staphylokinase in baboons.

1 reference

12 December 2020

Plasmhogen Activators from the Saliva of Desmodus rotundus (Common Vampire Bat): Unique Fibrin Specificity

1 reference

12 December 2020

Dose finding with a novel recombinant plasminogen activator (BM 06.022) in patients with acute myocardial infarction: results of the German Recombinant Plasminogen Activator Study. A study of the Arbeitsgemeinschaft Leitender Kardiologischer Kranken

1 reference

12 December 2020

A synthetic DNA encoding a modified human urokinase resistant to inhibition by serum plasminogen activator inhibitor

1 reference

12 December 2020

Sustained reflow in dogs with coronary thrombosis with K2P, a novel mutant of tissue-plasminogen activator

1 reference

12 December 2020

Comparison of the thrombolytic activity of the novel plasminogen activator, LY210825, to anisoylated plasminogen-streptokinase activator complex in a canine model of coronary artery thrombolysis

1 reference

12 December 2020

Thrombolytic profiles of clot-targeted plasminogen activators. Parameters determining potency and initial and maximal rates

1 reference

12 December 2020

Construction and expression of hybrid plasminogen activators prepared from tissue-type plasminogen activator and urokinase-type plasminogen activator genes

1 reference

12 December 2020

Effective thrombolysis without marked plasminemia after bolus intravenous administration of vampire bat salivary plasminogen activator in rabbits

1 reference

12 December 2020

The endothelial cell tissue plasminogen activator receptor. Specific interaction with plasminogen

1 reference

12 December 2020

Dependence of fibrinolytic activity on the concentration of free rather than total tissue-type plasminogen activator in plasma after pharmacologic administration

1 reference

12 December 2020

A recombinant chimeric plasminogen activator with high affinity for fibrin has increased thrombolytic potency in vitro and in vivo

1 reference

12 December 2020

A tissue-type plasminogen activator mutant with prolonged clearance in vivo. Effect of removal of the growth factor domain

1 reference

12 December 2020

Open, noncontrolled dose-finding study with a novel recombinant plasminogen activator (BM 06.022) given as a double bolus in patients with acute myocardial infarction.

1 reference

12 December 2020

Pharmacokinetics and thrombolytic properties of a nonglycosylated mutant of human tissue-type plasminogen activator, lacking the finger and growth factor domains, in dogs with copper coil-induced coronary artery thrombosis

1 reference

12 December 2020

Antibody-enhanced thrombolysis: targeting of tissue plasminogen activator in vivo

1 reference

12 December 2020

A hybrid plasminogen activator binds to the u-PA receptor and has a reduced thrombolytic potency in vivo

1 reference

12 December 2020

Staphylokinase, a fibrin-specific plasminogen activator with therapeutic potential?

1 reference

12 December 2020

Amino acid sequence of fibrolase, a direct‐acting fibrinolytic enzyme from agkistrodon contortrix contortrix venom

1 reference

12 December 2020

Pharmacokinetic and thrombolytic properties of chimeric plasminogen activators consisting of a single-chain Fv fragment of a fibrin-specific antibody fused to single-chain urokinase

1 reference

12 December 2020

Characterization of a chimeric plasminogen activator consisting of a single-chain Fv fragment derived from a fibrin fragment D-dimer-specific antibody and a truncated single-chain urokinase

1 reference

12 December 2020

Thrombolytic properties of a novel modified human tissue-type plasminogen activator (E6010): a bolus injection of E6010 has equivalent potency of lysing young and aged canine coronary thrombi

1 reference

12 December 2020

Innovative approaches to plasminogen activator therapy

1 reference

12 December 2020

10.2165/00003495-199550010-00003

Identifiers

DOI

1 reference

Dimensions Publication ID

20 September 2017

1012296690

0 references

1 reference